Hypophosphatemia secondary to oral refeeding in anorexia nervosa
Article first published online: 11 JUL 2000
Copyright © 2000 John Wiley & Sons, Inc.
International Journal of Eating Disorders
Volume 28, Issue 2, pages 181–187, September 2000
How to Cite
Fisher, M., Simpser, E. and Schneider, M. (2000), Hypophosphatemia secondary to oral refeeding in anorexia nervosa. Int. J. Eat. Disord., 28: 181–187. doi: 10.1002/1098-108X(200009)28:2<181::AID-EAT7>3.0.CO;2-K
- Issue published online: 11 JUL 2000
- Article first published online: 11 JUL 2000
- Manuscript Accepted: 10 NOV 1998
- anorexia nervosa
Hypophosphatemia is a well-known complication of the refeeding syndrome in severe cases of anorexia nervosa, described mostly as a result of refeeding with total parenteral nutrition. Few cases have been reported secondary to either nasogastric or oral refeeding.
The authors present three cases in which hypophosphatemia developed secondary to oral refeeding in severe anorexia nervosa.
All 3 patients developed significant hypophosphatemia, to a low of 0.9 mg/dl in two cases and a low of 1.7 mg/dl in the third. The first patient received close to 3,000 calories per day, along with intravenous fluids, in the hospital; the other 2 patients ate large amounts for several days at home. Caloric restriction and replenishment with phosphorous resulted in a rapid return of phosphorous values to normal levels.
Those who treat severely malnourished patients with eating disorders, whether as inpatients or outpatients, need to be vigilant for the development of the refeeding syndrome, even in patients receiving oral refeeding alone. © 2000 by John Wiley & Sons, Inc. Int J Eat Disord 28: 181–187, 2000.