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Mutagenic Agents

  1. Wolfgang Pfau

Published Online: 15 JUL 2012

DOI: 10.1002/14356007.a16_755.pub3

Ullmann's Encyclopedia of Industrial Chemistry

Ullmann's Encyclopedia of Industrial Chemistry

How to Cite

Pfau, W. 2012. Mutagenic Agents. Ullmann's Encyclopedia of Industrial Chemistry. .

Author Information

  1. GAB Consulting GmbH, Lamstedt, Germany

Publication History

  1. Published Online: 15 JUL 2012

Abstract

The article contains sections titled:

1.Introduction
2.Mutagenesis
2.1.Gene Mutations
2.1.1.Point Mutations
2.1.2.Frameshift Mutations
2.2.Chromosomal Aberrations
2.3.Genome Mutations
3.DNA Repair
4.Mutations and Cancer
5.Mutagenicity Tests
5.1.Microbial Tests
5.2.Eukaryotic In Vitro Tests
5.2.1.Mammalian Gene Mutagenicity Tests
5.2.2.In Vitro Cytogenetic Assays
5.3.In Vivo Tests
5.3.1.Micronucleus Assay
5.3.2.Germ-Cell Tests
5.3.3.Indicator Tests
5.3.4.Transgenic Animals
6.Testing Strategies
7.Metabolic Activation
8.Types of Mutagenic Agents
9.Conclusions