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Chromatographic Reactors

  1. Jörg Fricke1,
  2. Henner Schmidt-Traub2,
  3. Gerhard Schembecker2

Published Online: 15 JUL 2008

DOI: 10.1002/14356007.c07_c01.pub2

Ullmann's Encyclopedia of Industrial Chemistry

Ullmann's Encyclopedia of Industrial Chemistry

How to Cite

Fricke, J., Schmidt-Traub, H. and Schembecker, G. 2008. Chromatographic Reactors. Ullmann's Encyclopedia of Industrial Chemistry. .

Author Information

  1. 1

    Bayer CropScience Aktiengesellschaft, Monheim, Germany

  2. 2

    Technische Universität Dortmund, Department of Bio- and Chemical Engineering, Dortmund, Germany

Publication History

  1. Published Online: 15 JUL 2008

Abstract

Chromatographic reactors integrate chemical reaction and chromatographic separation in one apparatus. This offers potential for process intensification, especially in the case of equilibrium reactions. Different types of discontinuous and continuous processes as well as modeling of chromatographic reactors are described. Synthesis and design of this processes is very much influenced and often restricted by the type of reaction and the operating window which is set by the individual operating conditions for chemical reaction, mass separation, and equipment design. Integrated chromatographic reactors should be considered if chromatography is the favored separation process for a conventional sequential process design. Preparative chromatographic reactors are known for liquid- and gas-phase processes. Laboratory-scale applications are described. Analytical chromatographic reactors are used to determine reaction rate constants and kinetics, and to screen chromatographic systems and operating conditions for preparative applications.

1.Introduction
2.Types of Chromatographic Reactors
3.Modeling of Chromatographic Reactors
3.1.Adsorption Isotherm and Reaction Kinetics
3.2.Modeling the BCR
3.3.Modeling Simulated Moving Bed Chromatographic Reactors
3.4.Process control
4.Synthesis of Preparative Chromatographic Reactors
4.1.Process Principles
4.2.Type of Reaction
5.Design of Preparative Chromatographic Reactors
5.1.Design of the Process
5.2.Choice of Operating Conditions
6.Preparative Chromatographic Reactors
6.1.Applications of Gas Chromatographic Reactors
6.2.Application of Liquid Chromatographic Reactors
7.Analytical Chromatographic Reactors
7.1.Determination of Rate Constants
7.2.Enzymatic Reactions
7.3.Characterization of the Stationary Phase
7.4.Examination of Fast Equilibrium Reactions
7.5.Examination of Solvent Effects