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Antibiotics, 2. Production

  1. Heinz Öppinger1,
  2. Hinrich Hoffmann1,
  3. Dieter Sukatsch1,
  4. Leo Hepner2,
  5. Celia Male2

Published Online: 15 OCT 2011

DOI: 10.1002/14356007.o02_o08

Ullmann's Encyclopedia of Industrial Chemistry

Ullmann's Encyclopedia of Industrial Chemistry

How to Cite

Öppinger, H., Hoffmann, H., Sukatsch, D., Hepner, L. and Male, C. 2011. Antibiotics, 2. Production. Ullmann's Encyclopedia of Industrial Chemistry. .

Author Information

  1. 1

    Hoechst Aktiengesellschaft, Frankfurt, Germany

  2. 2

    L. Hepner and Associates, Ltd., London, United Kingdom

Publication History

  1. Published Online: 15 OCT 2011

This is not the most recent version of the article. View current version (25 JUL 2016)

Abstract

The article contains sections titled:

1.Fermentation
1.1.Screening
1.2.Selection, Mutation, and Maintenance of Strains
1.3.Process Development Leading to Large-Scale Production
1.4.Fermentation Technology
1.4.1.Maintenance of the Strain and Production of Inoculum
1.4.2.Treatment Before and During Fermentation
2.Isolation and Purification of Antibiotics; Quality Specifications
2.1.Isolation
2.2.Purification Techniques, Sterile End Products, Official Regulations
3.Analytical Measurements and Quality Control
3.1.Microbiological Analysis
3.2.Isotopically Labeled Antibiotics
4.Economic Aspects