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Anti-D administration in pregnancy for preventing Rhesus alloimmunisation

  1. Caroline A Crowther*,
  2. Philippa Middleton,
  3. Rosemary D McBain

Editorial Group: Cochrane Pregnancy and Childbirth Group

Published Online: 28 FEB 2013

Assessed as up-to-date: 14 NOV 2012

DOI: 10.1002/14651858.CD000020.pub2


How to Cite

Crowther CA, Middleton P, McBain RD. Anti-D administration in pregnancy for preventing Rhesus alloimmunisation. Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD000020. DOI: 10.1002/14651858.CD000020.pub2.

Author Information

  1. The University of Adelaide, ARCH: Australian Research Centre for Health of Women and Babies, Discipline of Obstetrics and Gynaecology, Adelaide, South Australia, Australia

*Caroline A Crowther, ARCH: Australian Research Centre for Health of Women and Babies, Discipline of Obstetrics and Gynaecology, The University of Adelaide, Women's and Children's Hospital, 72 King William Road, Adelaide, South Australia, 5006, Australia. caroline.crowther@adelaide.edu.au.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 28 FEB 2013

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[Figure 1]
Figure 1. 'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
[Figure 2]
Figure 2. 'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Anti-D administration in pregnancy, Outcome 1 Immunisation in pregnancy.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Anti-D administration in pregnancy, Outcome 2 Immunisation after birth of a Rhesus-positive infant.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Anti-D administration in pregnancy, Outcome 3 Immunisation at 2-12 months.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Anti-D administration in pregnancy, Outcome 4 Immunisation at 2-12 months - primigravidae alone.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Anti-D administration in pregnancy, Outcome 5 Positive Kleihauer at 32-35 weeks.
[Analysis 1.6]
Analysis 1.6. Comparison 1 Anti-D administration in pregnancy, Outcome 6 Positive Kleihauer at birth of a Rhesus-positive infant.
[Analysis 1.7]
Analysis 1.7. Comparison 1 Anti-D administration in pregnancy, Outcome 7 Kleihauer > 1/10,000 - Rhesus-positive infant.
[Analysis 1.8]
Analysis 1.8. Comparison 1 Anti-D administration in pregnancy, Outcome 8 Neonatal jaundice.