Creams for preventing stretch marks in pregnancy

  • Review
  • Intervention

Authors


Abstract

Background

Striae gravidarum (stretch marks developing during pregnancy) occur in over 50% of women. There is no evidence that any treatment removes striae once they have appeared. Some women are upset about the change in the appearance of their skin.

Objectives

To assess the effects of topical treatments in preventing the development of stretch marks.

Search methods

We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (April 2004). We updated this search on 1 October 2009 and added the results to the awaiting classification section.

Selection criteria

Randomised trials comparing active creams with either no treatment or placebo for the treatment of stretch marks in pregnant women.

Data collection and analysis

Two review authors assessed trial quality and extracted data independently.

Main results

Two studies, involving 130 women in total, were included.

One study, involving 80 women, indicated that, compared to placebo, massage with a cream (Trofolastin) containing Centella asiatica extract, alpha tocopherol and collagen-elastin hydrolysates was associated with less women developing stretch marks (odds ratio (OR) 0.41, 95% confidence interval (CI) 0.17 to 0.99). A second study of 50 women compared massage using an ointment (Verum) containing tocopherol, panthenol, hyaluronic acid, elastin and menthol with no treatment. Massage with the ointment was associated with less women developing stretch marks (OR 0.26, 95% CI 0.08 to 0.84)

Authors' conclusions

Trofolastin cream appears to help prevent the development of stretch marks in pregnancy in some women. Verum ointment may be helpful but the trial had no placebo and may show the benefit of massage alone.

[Note: The three citations in the awaiting classification section of the review may alter the conclusions of the review once assessed.]

摘要

背景

懷孕時防止妊娠紋之除紋霜

妊娠紋(於妊娠時產生的伸展紋)發生於超過一半的女性。目前並無任何證據顯示有辦法除去這些紋路。而某些女性對於她們皮膚有如此的改變感到厭惡

目標

為評估使用局部藥膏來防止妊娠紋產生之效果

搜尋策略

我們搜尋了Cochrane Pregnancy and Childbirth Group trials註冊資料庫(2004年4月)

選擇標準

比較積極使用除妊娠霜與無任何治療或安慰劑的(孕婦)隨機試驗

資料收集與分析

本文兩位作者評估試驗的品質並獨立地摘錄資料

主要結論

我們收納了總共130位女性的兩篇文獻。其中一篇包含80位女性的研究指出使用centella asiatica萃取物、alpha tocopherol與collagenelastin hydrolysates的除紋霜(Trofolastin)來按摩和較少的妊娠紋發生有相關(O .41,95% confidence interval (CI) 0.17 to 0.99)。第二篇研究包含50位女性,比較併用含tocopherol、panthenol、hyaluronic acid、elastin與menthol的軟膏按摩和不治療的差別。併用軟膏的按摩和較少的妊娠紋發生有相關(OR 0.26, 98% CI 0.08 to 0.84)

作者結論

Trofolastin霜在一些懷孕婦女中顯現出可幫助預防妊娠紋的發生。Verum軟膏則可能有些幫助,因為它的試驗並不包括安慰劑,故而顯示出單獨按摩可能也有益處

翻譯人

本摘要由周產期醫學會(Taiwan Society of Perinatology)張致遠翻譯

此翻譯計畫由臺灣國家衛生研究院(National Health Research Institutes, Taiwan)統籌

總結

某些婦女藉由每天的按摩可能防止妊娠紋的發生,但是否是特殊的成分而造成特別的效益則仍未清楚。於懷孕末期,妊娠紋是常見且發生於大部分的婦女。雖然妊娠紋之後會有某些程度地縮小與變淡,但卻不會完全消失。因此,任何可以防止妊娠紋產生的治療對很多婦女而言都是受歡迎的。這兩篇文獻可能顯示出任何對腹部、大腿與胸部(會受妊娠紋較大影響的區域)用來按摩的除紋霜可能有些幫助。在除紋霜及軟膏中某些成分可能有額外的益處,但是哪個成分有效則不清楚。這兩者皆未廣泛的使用

Plain language summary

Creams for preventing stretch marks in pregnancy

Stretch marks may be prevented in some women by daily massage but it is unclear if any particular ingredients bring special benefit.

Stretch marks are common by the end of pregnancy, occurring in most women. Though they later shrink and fade somewhat, they do not go away. Therefore, any treatment which prevented them would be welcomed by many women. The two papers reviewed may show that any cream massaged onto the abdomen, thighs and breasts (areas most affected by stretch marks) may help a little. There may be additional benefit from certain ingredients in the cream and the ointment described but it is unknown which constituent(s) is beneficial. Neither preparation is widely available.

Ancillary