Fetal electrocardiogram (ECG) for fetal monitoring during labour

  • Review
  • Intervention

Authors

  • James P Neilson

    Corresponding author
    1. The University of Liverpool, Department of Women's and Children's Health, Liverpool, UK
    • James P Neilson, Department of Women's and Children's Health, The University of Liverpool, First Floor, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, L8 7SS, UK. jneilson@liverpool.ac.uk.

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Abstract

Background

Hypoxaemia during labour can alter the shape of the fetal electrocardiogram (ECG) waveform, notably the relation of the PR to RR intervals, and elevation or depression of the ST segment. Technical systems have therefore been developed to monitor the fetal ECG during labour as an adjunct to continuous electronic fetal heart rate monitoring with the aim of improving fetal outcome and minimising unnecessary obstetric interference.

Objectives

To compare the effects of analysis of fetal ECG waveforms during labour with alternative methods of fetal monitoring.

Search methods

The Cochrane Pregnancy and Childbirth Group's Trials Register (latest search 23 September 2015) and reference lists of retrieved studies.

Selection criteria

Randomised trials comparing fetal ECG waveform analysis with alternative methods of fetal monitoring during labour.

Data collection and analysis

One review author independently assessed trials for inclusion and risk of bias, extracted data and checked them for accuracy. One review author assessed the quality of the evidence using the GRADE approach.

Main results

Seven trials (27,403 women) were included: six trials of ST waveform analysis (26,446 women) and one trial of PR interval analysis (957 women). The trials were generally at low risk of bias for most domains and the quality of evidence for ST waveform analysis trials was graded moderate to high. In comparison to continuous electronic fetal heart rate monitoring alone, the use of adjunctive ST waveform analysis made no obvious difference to primary outcomes: births by caesarean section (risk ratio (RR) 1.02, 95% confidence interval (CI) 0.96 to 1.08; six trials, 26,446 women; high quality evidence); the number of babies with severe metabolic acidosis at birth (cord arterial pH less than 7.05 and base deficit greater than 12 mmol/L) (average RR 0.72, 95% CI 0.43 to 1.20; six trials, 25,682 babies; moderate quality evidence); or babies with neonatal encephalopathy (RR 0.61, 95% CI 0.30 to 1.22; six trials, 26,410 babies; high quality evidence). There were, however, on average fewer fetal scalp samples taken during labour (average RR 0.61, 95% CI 0.41 to 0.91; four trials, 9671 babies; high quality evidence) although the findings were heterogeneous and there were no data from the largest trial (from the USA). There were marginally fewer operative vaginal births (RR 0.92, 95% CI 0.86 to 0.99; six trials, 26,446 women); but no obvious difference in the number of babies with low Apgar scores at five minutes or babies requiring neonatal intubation, or babies requiring admission to the special care unit (RR 0.96, 95% CI 0.89 to 1.04, six trials, 26,410 babies; high quality evidence). There was little evidence that monitoring by PR interval analysis conveyed any benefit of any sort.

Authors' conclusions

The modest benefits of fewer fetal scalp samplings during labour (in settings in which this procedure is performed) and fewer instrumental vaginal births have to be considered against the disadvantages of needing to use an internal scalp electrode, after membrane rupture, for ECG waveform recordings. We found little strong evidence that ST waveform analysis had an effect on the primary outcome measures in this systematic review.

There was a lack of evidence showing that PR interval analysis improved any outcomes; and a larger future trial may possibly demonstrate beneficial effects.

There is little information about the value of fetal ECG waveform monitoring in preterm fetuses in labour. Information about long-term development of the babies included in the trials would be valuable.

Plain language summary

Fetal electrocardiogram (ECG) for fetal monitoring during labour

Monitoring the baby's heart using electrocardiography (ECG) plus cardiotocography (CTG) during labour provides some modest help for mothers and babies when continuous monitoring is needed.

Strong uterine contractions during labour reduce the flow of maternal blood to the placenta. The umbilical cord may also be compressed during labour, especially if the membranes are ruptured. Usually the baby has sufficient reserve to withstand this effect but some may become distressed. Electronic heart monitoring may be suggested if the doctors think the baby is not getting enough oxygen during labour. Two different methods may be used. CTG measures the baby's heart rate together with the mother's uterine contractions. An ECG measures the heart's electrical activity and the pattern of the heart beats. This involves an electrode being passed through the woman's cervix and attached to the baby's head. This review of seven randomised controlled trials, including a total of 27,403 women, found that monitoring the baby using  ECG plus CTG resulted in fewer blood samples needing to be taken from the baby's scalp, and less surgical assistance with the birth, than with CTG alone. There was no difference in the number of caesarean deliveries and little to suggest that babies were in better condition at birth. The evidence was found to be of high quality.

Резюме на простом языке

Фетальные электрокардиограммы (ЭКГ) для мониторинга состояния плода во время родов

Мониторирование деятельности сердца ребенка с помощью электрокардиографии (ЭКГ) и кардиотокографии (КТГ) во время родов немного помогает матерям и младенцам, когда необходим непрерывный мониторинг.

Сильные сокращения матки во время родов уменьшают кровоток в плаценте (интенсивность тока материнской крови). Во время родов может быть и компрессия пуповины (пережатие), особенно при разрыве плодного пузыря. Обычно резервы ребенка бывают достаточны, чтобы выдержать это, но у некоторых детей может развиться дистресс. Если врачи полагают, что ребенок в родах не получает достаточно кислорода, они могут предложить электронный мониторинг деятельности сердца. Могут быть использованы два различных метода. КТГ измеряет частоту сердечных сокращений ребенка вместе с сокращениями матки матери. ЭКГ измеряет электрическую активность сердца и картину (ритм) сердечных сокращений. Для этого через шейку матки женщины к голове ребенка подводят и прикрепляют электрод. Этот обзор семи рандомизированных контролируемых испытаний, включивших в общей сложности 27403 женщин, показал, что мониторинг состояния ребенка с помощью  ЭКГ и КТГ привел к уменьшению числа образцов крови, которую нужно было забирать из сосудов головы ребенка, и к меньшему числу случаев хирургического родовспоможения, чем при использовании только КТГ. Не было разницы по числу операций кесарева сечения и было мало оснований, чтобы предположить, что младенцы были в лучшем состоянии при рождении. Эти доказательства были высокого качества.

Заметки по переводу

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