Intervention Review

Plasma volume expansion for suspected impaired fetal growth

  1. Lale Say1,*,
  2. A Metin Gülmezoglu2,
  3. G Justus Hofmeyr3

Editorial Group: Cochrane Pregnancy and Childbirth Group

Published Online: 21 JAN 2009

Assessed as up-to-date: 4 MAY 2010

DOI: 10.1002/14651858.CD000167

How to Cite

Say L, Gülmezoglu AM, Hofmeyr GJ. Plasma volume expansion for suspected impaired fetal growth. Cochrane Database of Systematic Reviews 1996, Issue 4. Art. No.: CD000167. DOI: 10.1002/14651858.CD000167.

Author Information

  1. 1

    World Health Organization, Department of Reproductive Health and Research, Geneva, Switzerland

  2. 2

    World Health Organization, UNDP/UNFPA/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction, Department of Reproductive Health and Research, Geneva, Switzerland

  3. 3

    University of the Witwatersrand, University of Fort Hare, Eastern Cape Department of Health, Department of Obstetrics and Gynaecology, East London Hospital Complex, East London, Eastern Cape, South Africa

*Lale Say, Department of Reproductive Health and Research, World Health Organization, 20 Avenue Appia, Geneva, 1211, Switzerland. sayl@who.int.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 21 JAN 2009

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Abstract

  1. Top of page
  2. Abstract
  3. Plain language summary
  4. 摘要

Background

Failure of the normal expansion of plasma volume in the mother is associated with impaired fetal growth and pre-eclampsia.

Objectives

The objective of this review was to assess the effects of plasma volume expansion for suspected impaired fetal growth.

Search methods

We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (March 2010).

Selection criteria

Randomized or quasi-randomized trials of plasma volume expansion compared to no plasma volume expansion in women with suspected impaired fetal growth.

Data collection and analysis

Trial quality was assessed.

Main results

No studies were included.

Authors' conclusions

There is not enough evidence to evaluate the use of plasma volume expansion for suspected impaired fetal growth.

 

Plain language summary

  1. Top of page
  2. Abstract
  3. Plain language summary
  4. 摘要

Plasma volume expansion for suspected impaired fetal growth

Too little evidence to show whether it is beneficial for pregnant women to have extra plasma when the baby is growing more slowly than expected.

Plasma is the fluid that carries the blood cells in the body. The amount of plasma and blood cells (the blood) circulating in a woman's body can double during pregnancy. Sometimes, women whose babies are growing too slowly during pregnancy (impaired fetal growth) do not have as much blood circulating in their body as would be expected. Plasma volume expansion is where solutions are injected into the woman's bloodstream to increase plasma levels. No trials were found to show whether plasma volume expansion is beneficial for these women or their babies.

 

摘要

  1. Top of page
  2. Abstract
  3. Plain language summary
  4. 摘要

背景

對於潛在的胎兒發育不全狀況所使用的血漿容積增加法(plasma volume expansion)

母親身上的血漿容積無法正常地增加時,與胎兒的發育不全以及子癲前症(preeclampsia)有關

目標

本篇回顧的目的,是要評估針對潛在的胎兒發育不全狀況所使用的血漿容積增加法之影響

搜尋策略

我們搜尋了the Cochrane Pregnancy and Childbirth Group's Trials Register (2006年11月)

選擇標準

在被懷疑有胎兒發育不全狀況之孕婦身上,由這些隨機或是半隨機的試驗,將血漿容積增加法與不使用血漿容積增加法來進行比較

資料收集與分析

我們評估了試驗的品質

主要結論

其中沒有找到任何符合的研究

作者結論

針對潛在的胎兒發育不全狀況,並沒有足夠的證據來評估血漿容積增加法的使用

翻譯人

此翻譯計畫由臺灣國家衛生研究院(National Health Research Institutes, Taiwan)統籌

總結

當嬰兒的成長速度比預期中慢得多時,證據太少而不足以顯示更多的血漿是否會對孕婦有利。血漿是身體內用來運送血球的液體。在一名婦女體內循環之血漿與血球的數量(血液),可以在懷孕期間變成雙倍。有時候,對於在懷孕期間的婦女來說,如果她們的嬰兒生長得太慢的話(胎兒發育不全),我們就可以這樣推測說,在她們的體內並沒有如預期足夠的血液在循環。血漿容積增加法是指將溶液注射到孕婦的血液之中,以增加血漿的含量。對於這些婦女或是她們的嬰兒來說,並沒有任何試驗可以證實血漿容積增加法是否有利