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Intervention Review

Ultrasound for fetal assessment in early pregnancy

  1. James P Neilson*

Editorial Group: Cochrane Pregnancy and Childbirth Group

Published Online: 23 APR 2008

Assessed as up-to-date: 27 JUN 2001

DOI: 10.1002/14651858.CD000182

How to Cite

Neilson JP. Ultrasound for fetal assessment in early pregnancy. Cochrane Database of Systematic Reviews 1998, Issue 4. Art. No.: CD000182. DOI: 10.1002/14651858.CD000182.

Author Information

  1. The University of Liverpool, School of Reproductive and Developmental Medicine, Division of Perinatal and Reproductive Medicine, Liverpool, UK

*James P Neilson, School of Reproductive and Developmental Medicine, Division of Perinatal and Reproductive Medicine, The University of Liverpool, First Floor, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, L8 7SS, UK. jneilson@liverpool.ac.uk.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 23 APR 2008

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Abstract

  1. Top of page
  2. Abstract
  3. Plain language summary

Background

Advantages of early pregnancy ultrasound screening are thought to be more accurate calculation of gestational age, earlier identification of multiple pregnancies, and diagnosis of non-viable pregnancies and certain fetal malformations.

Objectives

The objective of this review was to assess the use of routine (screening) ultrasound compared with the selective use of ultrasound in early pregnancy (ie before 24 weeks).

Search strategy

The Cochrane Pregnancy and Childbirth Group trials register and the Cochrane Controlled Trials Register (up to June 2001) were searched.

Selection criteria

Adequately controlled trials of routine ultrasound imaging in early pregnancy.

Data collection and analysis

One reviewer assessed trial quality and extracted data. Study authors were contacted for additional information.

Main results

Nine trials were included. The quality of the trials was generally good. Routine ultrasound examination was associated with earlier detection of multiple pregnancies (twins undiagnosed at 26 weeks, odds ratio 0.08, 95% confidence interval 0.04 to 0.16) and reduced rates of induction of labour for post-term pregnancy (odds ratio 0.61, 95% confidence interval 0.52 to 0.72). There were no differences detected for substantive clinical outcomes such as perinatal mortality (odds ratio 0.86, 95% confidence interval 0.67 to 1.12). Where detection of fetal abnormality was a specific aim of the examination, the number of terminations of pregnancy for fetal anomaly increased.

Authors' conclusions

Routine ultrasound in early pregnancy appears to enable better gestational age assessment, earlier detection of multiple pregnancies and earlier detection of clinically unsuspected fetal malformation at a time when termination of pregnancy is possible. However, the benefits for other substantive outcomes are less clear.

 

Plain language summary

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  2. Abstract
  3. Plain language summary

Ultrasound for fetal assessment in early pregnancy

A plain language summary will be prepared for publication with the updated review.