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Intervention Review

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Antibiotic prophylaxis for surgery for proximal femoral and other closed long bone fractures

  1. William J Gillespie1,*,
  2. Geert Walenkamp2

Editorial Group: Cochrane Bone, Joint and Muscle Trauma Group

Published Online: 21 JAN 2009

Assessed as up-to-date: 25 NOV 2000

DOI: 10.1002/14651858.CD000244

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How to Cite

Gillespie WJ, Walenkamp G. Antibiotic prophylaxis for surgery for proximal femoral and other closed long bone fractures. Cochrane Database of Systematic Reviews 2001, Issue 1. Art. No.: CD000244. DOI: 10.1002/14651858.CD000244.

Author Information

  1. 1

    University of Hull, Hull York Medical School, Hull, UK

  2. 2

    Academisch Ziekenhuis Maastricht, Orthopaedics, Maastricht , Maastricht, Netherlands

*William J Gillespie, Hull York Medical School, University of Hull, Cottingham Road, Hull, HU6 7RX, UK. bill.gillespie@hyms.ac.uk. bill.gillespie@yahoo.co.nz.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 21 JAN 2009

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This is not the most recent version of the article.View current version (17 Mar 2010)

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[Analysis 1.1]
Analysis 1.1. Comparison 1 Antibiotic agent (mulitple dose) versus placebo or no treatment, Outcome 1 Deep wound infection.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Antibiotic agent (mulitple dose) versus placebo or no treatment, Outcome 2 Superficial wound infection.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Antibiotic agent (mulitple dose) versus placebo or no treatment, Outcome 3 Urinary tract infection.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Antibiotic agent (mulitple dose) versus placebo or no treatment, Outcome 4 Respiratory infection.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Antibiotic agent (mulitple dose) versus placebo or no treatment, Outcome 5 Adverse drug effects.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Antibiotic agent (single dose) versus placebo or no treatment, Outcome 1 Deep wound infection.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Antibiotic agent (single dose) versus placebo or no treatment, Outcome 2 Superficial wound infection.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Antibiotic agent (single dose) versus placebo or no treatment, Outcome 3 Urinary tract infection.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Antibiotic agent (single dose) versus placebo or no treatment, Outcome 4 Respiratory infection.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Single dose short-acting versus multiple dose - same agent, Outcome 1 Deep wound infection.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Single dose short-acting versus multiple dose - same agent, Outcome 2 Superficial wound infection.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Single dose short-acting versus multiple dose - same agent, Outcome 3 Urinary tract infection.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Single dose long acting versus any multiple dose regimen, Outcome 1 Deep wound infection.
[Analysis 4.2]
Analysis 4.2. Comparison 4 Single dose long acting versus any multiple dose regimen, Outcome 2 Superficial wound infection.
[Analysis 4.3]
Analysis 4.3. Comparison 4 Single dose long acting versus any multiple dose regimen, Outcome 3 Urinary tract infection.
[Analysis 4.4]
Analysis 4.4. Comparison 4 Single dose long acting versus any multiple dose regimen, Outcome 4 Respiratory infection.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Operative day only versus longer prophylaxis, Outcome 1 Deep wound infection.
[Analysis 5.2]
Analysis 5.2. Comparison 5 Operative day only versus longer prophylaxis, Outcome 2 Superficial wound infection.
[Analysis 6.1]
Analysis 6.1. Comparison 6 Oral versus parenteral administration of antibiotic agent, Outcome 1 Deep wound infection.
[Analysis 6.2]
Analysis 6.2. Comparison 6 Oral versus parenteral administration of antibiotic agent, Outcome 2 Superficial wound infection.
[Analysis 6.3]
Analysis 6.3. Comparison 6 Oral versus parenteral administration of antibiotic agent, Outcome 3 Urinary tract infection.
View Full Article (HTML) Summary (58K)Standard (299K)Full (421K)