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Antibiotics for the common cold and acute purulent rhinitis

  1. Tim Kenealy*,
  2. Bruce Arroll

Editorial Group: Cochrane Acute Respiratory Infections Group

Published Online: 4 JUN 2013

Assessed as up-to-date: 26 FEB 2013

DOI: 10.1002/14651858.CD000247.pub3


How to Cite

Kenealy T, Arroll B. Antibiotics for the common cold and acute purulent rhinitis. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD000247. DOI: 10.1002/14651858.CD000247.pub3.

Author Information

  1. University of Auckland, Department of General Practice and Primary Health Care, Auckland, New Zealand

*Tim Kenealy, Department of General Practice and Primary Health Care, University of Auckland, Private Bag 92019, Auckland, New Zealand. t.kenealy@cochraneprimarycare.org.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 4 JUN 2013

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[Figure 1]
Figure 1. 'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
[Figure 2]
Figure 2. 'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Antibiotic versus placebo, common cold, Outcome 1 Persisting symptoms 1 to 7 days.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Antibiotic versus placebo, common cold, Outcome 2 Persisting symptoms day 1 to 7 with Herne out.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Antibiotic versus placebo, common cold, Outcome 3 Persisting symptoms days 1 to 7 in adults.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Antibiotic versus placebo, common cold, Outcome 4 Persisting symptoms day 1 to 7 children only.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Antibiotic versus placebo, common cold, Outcome 5 Persisting symptoms day 1 to 7 with Hoagland and McKerrow out.
[Analysis 1.6]
Analysis 1.6. Comparison 1 Antibiotic versus placebo, common cold, Outcome 6 Persisting symptoms 1 to 7 days with Kaiser out.
[Analysis 1.7]
Analysis 1.7. Comparison 1 Antibiotic versus placebo, common cold, Outcome 7 Adverse effects.
[Analysis 1.8]
Analysis 1.8. Comparison 1 Antibiotic versus placebo, common cold, Outcome 8 Adverse effects in adults.
[Analysis 1.9]
Analysis 1.9. Comparison 1 Antibiotic versus placebo, common cold, Outcome 9 Adverse effects in children.
[Analysis 1.10]
Analysis 1.10. Comparison 1 Antibiotic versus placebo, common cold, Outcome 10 Adverse effects with McKerrow out.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Antibiotic versus placebo, clear rhinitis, Outcome 1 Persistent rhinitis (clear) with Herne added as clear.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Antibiotic versus placebo, purulent rhinitis, Outcome 1 Persistent rhinitis (purulent).
[Analysis 3.2]
Analysis 3.2. Comparison 3 Antibiotic versus placebo, purulent rhinitis, Outcome 2 Persistent purulent rhinitis with Herne added as purulent.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Antibiotic versus placebo, purulent rhinitis, Outcome 3 Persistent purulent rhinitis with currently available medication.
[Analysis 3.4]
Analysis 3.4. Comparison 3 Antibiotic versus placebo, purulent rhinitis, Outcome 4 Adverse effects for purulent rhinitis studies.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Antibiotic versus placebo, sore throat, Outcome 1 Sore throat at day 7.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Antibiotic versus placebo, work loss, Outcome 1 Any work loss.
[Analysis 6.1]
Analysis 6.1. Comparison 6 Antibiotic versus placebo, loss of appetite, Outcome 1 Loss of appetite at day 8.