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Intervention Review

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Steroids for acute spinal cord injury

  1. Michael B Bracken*

Editorial Group: Cochrane Injuries Group

Published Online: 21 JAN 2009

Assessed as up-to-date: 19 SEP 2007

DOI: 10.1002/14651858.CD001046

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How to Cite

Bracken MB. Steroids for acute spinal cord injury. Cochrane Database of Systematic Reviews 2002, Issue 2. Art. No.: CD001046. DOI: 10.1002/14651858.CD001046.

Author Information

  1. Yale University Medical School, Department of Epidemiology & Public Health, New Haven, CT, USA

*Michael B Bracken, Department of Epidemiology & Public Health, Yale University Medical School, Box 20834, 60 College Street, New Haven, CT, 06520-8034, USA. michael.bracken@yale.edu.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 21 JAN 2009

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Bracken 1984/85 {published data only}
  • Bracken MB, Collins WF, Freeman DF, Shepard MJ, Wagner FW, Silten RM, et al. Efficacy of methylprednisolone in acute spinal cord injury. Journal of the American Medical Association 1984;251:45-52.
  • Bracken MB, Shepard MJ, Hellenbrand KG, Collins WF, Leo LS, Freeman DF, et al. Methylprednisolone and neurological function one year after spinal cord injury. Journal of Neurosurgery 1985;63:704-13.
Bracken 1990/93 {published data only}
Bracken 1997/98 {published data only}
  • Bracken MB, Shepard MJ, Holford TR, Leo-Summers L, Aldrich EF, Fazl M, et al. Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Results of the third National Acute Spinal Cord Injury randomized controlled trial. Journal of Neurosurgery 1998;89:699-706.
  • Bracken MB, Shepard MJ, Holford TR, Leo-Summers L, Aldrich EF, Fazl M, et al. Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the third national acute spinal cord injury randomized controlled trial. Journal of the American Medical Association 1997;277:1597-604.
Glasser 1993 {published data only}
Matsumoto 2001 {published data only}
  • Matsumoto T, Tamaki T, Kawakami M, Yoshida M, Ando M, Yamada H. Early complications of high dose methylprednisolone sodium succinate treatment in the follow-up of acute cervical spinal cord injury. Spine 2001;26(4):426-30.
Otani 1994 {published data only}
  • Otani K. Functional recovery: focus on upper and lower limbs (translation of Japanese). Journal of the Japanese Paraplegia Medicine Association 1995;8:80-1.
  • Otani K, Abe H, Kadoya S, et al. Beneficial effect of methylprednisolone sodium succinate in the treatment of acute spinal cord injury (translation of Japanese). Sekitsui Sekizui J 1994;7:633-47.
  • Yokota H, Kawai M, Kato K, et al. Significance of methylprednisolone therapy in acute spinal cord injury with special reference to short term follow-up (translation of Japanese). Journal of the Japanese Association of Acute Medicine 1995;6:349-54.
Petitjean 1998 {published data only}
  • Petitjean ME, Pointillart V, Dixmerias F, Wiart L, Sztark F, Lassie P, Thicoipe M, Dabadie P. Traitement medicamenteux de la lesion medullaire traumatique au stade aigu. Ann Fr Anesth Reanim 1998;17:115-22.
Pettersson 1998 {published data only}

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Kiwerski 1992 {published data only}
  • Kiwerski J. Zastosowanie dexametazonu w leczeniu uszkodzen rdzenia kregowego we wczesnym okresie pourazowym. Neur Neurochir Pol 1992;26:518-27.
Pointillart 2000 {published data only}
Yokota 1995 {published data only}
  • Yokota H, Kawai M, Kato K, Mashiko K, Yamamoto Y, Henmi H, Otsuka T. Significance of methylprednisolone therapy in acute spinal cord injury with special reference to short-term follow-up. Journal of the Japanese Association of Acute Medicine 1995;6:349-54.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
Berkowitz 1992
  • Berkowitz M, Harvey C, Greene CG, Wilson SE. The economic consequences of traumatic spinal cord injury. New York: Demos Publications, 1992.
Bracken 1981
  • Bracken MB, Freeman DH, Hellenbrand K. Incidence of acute traumatic hospitalized spinal cord injury in the United States 1970-1977. American Journal of Epidemiology 1981;133:615-22.
Bracken 2001
Ducker 1969
  • Ducker TB, Hamit HF. Experimental treatments of acute spinal cord injury. Journal of Neurosurgery 1969;30:693-722.
Follmann 1992
Hall 1992
Sauerland 2000
  • Sauerland S, Nagelschmidt M, Mallman P, et al. Risks and benefits of preoperative high dose methylprednisolone in surgical patients: a systematc review. Drug Safety 2000;55:452-3.
Sinclair 1992
  • Sinclair JC, Bracken MB (eds). Effective care of the newborn infant. Oxford: Oxford University Press, 1992:p9.
Wing 1998
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