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Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems

  1. G Justus Hofmeyr1,*,
  2. Álvaro N Atallah2,
  3. Lelia Duley3

Editorial Group: Cochrane Pregnancy and Childbirth Group

Published Online: 20 JAN 2010

Assessed as up-to-date: 1 MAR 2006

DOI: 10.1002/14651858.CD001059.pub2

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How to Cite

Hofmeyr GJ, Atallah ÁN, Duley L. Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems. Cochrane Database of Systematic Reviews 2006, Issue 3. Art. No.: CD001059. DOI: 10.1002/14651858.CD001059.pub2.

Author Information

  1. 1

    University of the Witwatersrand, University of Fort Hare, Eastern Cape Department of Health, Department of Obstetrics and Gynaecology, East London Hospital Complex, East London, Eastern Cape, South Africa

  2. 2

    Universidade Federal de São Paulo / Escola Paulista de Medicina, Brazilian Cochrane Centre, São Paulo, SP, Brazil

  3. 3

    University of Leeds, Centre for Epidemiology and Biostatistics, Bradford, West Yorkshire, UK

*G Justus Hofmeyr, Department of Obstetrics and Gynaecology, East London Hospital Complex, University of the Witwatersrand, University of Fort Hare, Eastern Cape Department of Health, Frere and Cecilia Makiwane Hospitals, Private Bag X 9047, East London, Eastern Cape, 5200, South Africa. gjh@global.co.za.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 20 JAN 2010

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[Analysis 1.1]
Analysis 1.1. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 1 High blood pressure (with or without proteinuria).
[Analysis 1.2]
Analysis 1.2. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 2 Pre-eclampsia.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 3 Maternal death/serious morbidity.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 4 Placental abruption.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 5 Caesarean section.
[Analysis 1.6]
Analysis 1.6. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 6 Proteinuria (gestational with no proteinuria.
[Analysis 1.7]
Analysis 1.7. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 7 Severe pre-eclamsia.
[Analysis 1.8]
Analysis 1.8. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 8 Eclampsia.
[Analysis 1.9]
Analysis 1.9. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 9 HELLP syndrome.
[Analysis 1.10]
Analysis 1.10. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 10 ICU admission.
[Analysis 1.11]
Analysis 1.11. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 11 Maternal death.
[Analysis 1.13]
Analysis 1.13. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 13 Preterm birth.
[Analysis 1.14]
Analysis 1.14. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 14 Birthweight < 2500 g.
[Analysis 1.15]
Analysis 1.15. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 15 Neonate small-for-gestational age as defined by trial authors.
[Analysis 1.16]
Analysis 1.16. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 16 Admission to neonatal intensive care unit.
[Analysis 1.18]
Analysis 1.18. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 18 Stillbirth or death before discharge from hospital.
[Analysis 1.21]
Analysis 1.21. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 21 Childhood systolic blood pressure > 95th percentile.
[Analysis 1.22]
Analysis 1.22. Comparison 1 Routine calcium supplementation in pregnancy by baseline dietary calcium, Outcome 22 Childhood diastolic blood pressure > 95th percentile.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Routine calcium supplementation in pregnancy by hypertension risk, Outcome 1 High blood pressure (with or without proteinuria).
[Analysis 2.2]
Analysis 2.2. Comparison 2 Routine calcium supplementation in pregnancy by hypertension risk, Outcome 2 Pre-eclampsia.
[Analysis 2.13]
Analysis 2.13. Comparison 2 Routine calcium supplementation in pregnancy by hypertension risk, Outcome 13 Preterm birth.
[Analysis 2.16]
Analysis 2.16. Comparison 2 Routine calcium supplementation in pregnancy by hypertension risk, Outcome 16 Admission to neonatal intensive care unit.
[Analysis 2.18]
Analysis 2.18. Comparison 2 Routine calcium supplementation in pregnancy by hypertension risk, Outcome 18 Stillbirth or death before discharge from hospital.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Routine calcium supplementation in pregnancy by study sample size, Outcome 1 High blood pressure (with or without proteinuria).
[Analysis 3.2]
Analysis 3.2. Comparison 3 Routine calcium supplementation in pregnancy by study sample size, Outcome 2 Pre-eclampsia.
[Analysis 3.13]
Analysis 3.13. Comparison 3 Routine calcium supplementation in pregnancy by study sample size, Outcome 13 Preterm birth.
[Analysis 3.16]
Analysis 3.16. Comparison 3 Routine calcium supplementation in pregnancy by study sample size, Outcome 16 Admission to neonatal intensive care unit.
[Analysis 3.18]
Analysis 3.18. Comparison 3 Routine calcium supplementation in pregnancy by study sample size, Outcome 18 Stillbirth or death before discharge from hospital.
[Analysis 4.2]
Analysis 4.2. Comparison 4 Routine calcium supplementation in pregnancy by baseline dietary calcium and study sample size, Outcome 2 Pre-eclampsia.
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