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Alendronate for osteoporosis in postmenopausal women

  • Protocol
  • Intervention



This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

To determine the efficacy of alendronate therapy in the prevention and treatment of postmenopausal osteoporosis.

The major endpoints will be: (1) reduction of vertebral and non-vertebral fractures, and (2) changes in bone mineral density (3) toxicity of alendronate.