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Antimicrobials for treating symptomatic non-typhoidal Salmonella infection

  1. Ifeanyi A Onwuezobe1,*,
  2. Philip O Oshun2,
  3. Chibuzo C Odigwe3

Editorial Group: Cochrane Infectious Diseases Group

Published Online: 14 NOV 2012

Assessed as up-to-date: 6 AUG 2012

DOI: 10.1002/14651858.CD001167.pub2


How to Cite

Onwuezobe IA, Oshun PO, Odigwe CC. Antimicrobials for treating symptomatic non-typhoidal Salmonella infection. Cochrane Database of Systematic Reviews 2012, Issue 11. Art. No.: CD001167. DOI: 10.1002/14651858.CD001167.pub2.

Author Information

  1. 1

    University of Uyo Teaching Hospital, Medical Microbiology and Parasitology, Uyo, Akwa Ibom State, Nigeria

  2. 2

    Lagos University Teaching Hospital, Department of Medical Microbiology, Lagos, Nigeria

  3. 3

    Institute of Tropical Disease Research & Prevention, Nigeria Effective Health Care Alliance Programme, Calabar, Cross River State, Nigeria

*Ifeanyi A Onwuezobe, Medical Microbiology and Parasitology, University of Uyo Teaching Hospital, Uyo, Akwa Ibom State, 1136, Nigeria. ifezobe@yahoo.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 14 NOV 2012

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Butler 1993 {published data only}
  • Butler T, Lolekha S, Rasidi C, Kadio A, Leal del Rosal P, Iskandar H, et al. Treatment of acute bacterial diarrhea: a multicenter international trial comparing placebo with fleroxacin given as a single dose or once daily for 3 days. American Journal of Medicine 1993;94(Suppl 3A):187s-94s.
Chiu 1999 {published data only}
Garcia de Olarte 1974 {published data only}
  • Garcia de Olarte D, Trujillo H, Agudelo N, Nelson JD, Haltalin KC. Treatment of diarrhea in malnourished infants and children: a double blind study comparing ampicillin and placebo. American Journal of Disease in Childhood 1974;127(3):379-88.
Goodman 1990 {published data only}
  • Goodman LJ, Trenholme GM, Kaplan RL, Segreti J, Hines D, Petrak R, et al. Empiric antimicrobial therapy of domestically acquired acute diarrhea in urban adults. Archives of Internal Medicine 1990;150(3):541-6.
Joint Project ASID 1970 {published data only}
  • Joint project by members of the Association for the Study of Infectious Disease. Effect of neomycin in non-invasive Salmonella infections of the gastrointestinal tract. Lancet 1970;2(7684):1159-61.
Kazemi 1973 {published data only}
  • Kazemi M, Gumpert TG, Marks MI. A controlled trial comparing sulfamethoxazole-trimethoprim, ampicillin, and no therapy in the treatment of Salmonella gastroenteritis in children. Journal of Pediatrics 1973;83(4):646-50.
Macdonald 1954 {published data only}
  • Macdonald WB, Friday F, McEacharn M. The effect of chloramphenicol in Salmonella enteritis of infancy. Archives of Disease in Childhood 1954;29(145):238-41.
Neil 1991 {published data only}
  • Neill MA, Opal SM, Heelan J, Giusti R, Cassidy JE, White R, et al. Failure of ciprofloxacin to eradicate convalescent fecal excretion after acute salmonellosis: experience during an outbreak in health care workers. Annals of Internal Medicine 1991;114(3):195-9.
Nelson 1980 {published data only}
Pitkajarvi 1996 {published data only}
  • Pitkajarvi T, Kujanne E, Sillantaka I, Lumio J. Norfloxacin and Salmonella excretion in acute gastroenteritis - a 6 month follow-up study. Scandinavian Journal of Infectious Diseases 1996;28(2):177-80.
Sanchez 1993 {published data only}
  • Sanchez C, Garcia-Restoy E, Garau J, Bella F, Freixas N, Simo M, et al. Ciprofloxacin and trimethoprim-sulfamethoxazole versus placebo in acute uncomplicated Salmonella enteritis: a double blind trial. Journal of Infectious Diseases 1993;168(5):1304-7.
Wistrom 1992 {published data only}
  • Wistrom J, Jertborn M, Ekwall E, Norlin K, Soderquist B, Stromberg A, et al. Empiric treatment of acute diarrheal disease with norfloxacin. Annals of Internal Medicine 1992;117(3):202-8.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Bessudo 1972 {published data only}
  • Bessudo D, Herrera Duarte A, Bucio R. Rifampicin in eradication of Salmonella from the intestinal tract. Chemotherapy 1972;17(1):71-8.
Carlstedt 1990 {published data only}
  • Carlstedt G, Dahl P, Niklasson PM, Gullberg K, Banck G, Kahlmeter G. Norfloxacin treatment of salmonellosis does not shorten the carrier stage. Scandinavian Journal of Infectious Diseases 1990;22(5):553-6.
Dryden 1996 {published data only}
  • Dryden MS, Gabb RJE, Wright SK. Empirical treatment of severe acute community-acquired gastroenteritis with ciprofloxacin. Clinical Infectious Diseases 1996;22(6):1019-25.
Ericsson 1983 {published data only}
  • Ericsson CD, Dupont HL, Sullivan P, Galindo E, Evans DG, Evans DJ Jr. Bizacomycin, a poorly absorbable antibiotic, effectively treats traveller's diarrhea. Annals of Internal Medicine 1983;98(1):20-5.
Hatalin 1972 {published data only}
  • Hatalin KC, Kusmiesz HT, Hinton LV, Nelson JD. Treatment of acute diarrhea in outpatients: double-blind study comparing ampicillin and placebo. American Journal of Disease in Childhood 1972;124(4):554-61.
Lolekha 1988 {published data only}
  • Lolekha S, Patanachareon S, Thanangkul B, Vibulbandhitkit S. Norfloxacin versus co-trimoxazole in the treatment of acute bacterial diarrhoea: a placebo controlled study. Scandinavian Journal of Infectious Diseases 1988;56(suppl):35-45.
Mattila 1993 {published data only}
  • Mattila L, Peltola H, Siitonen A, Kyronseppa H, Simula I, Kataja M. Short-term treatment of traveller's diarrhea with norfloxacin: a double-blind placebo controlled study during two seasons. Clinical Infectious Diseases 1993;17(4):779-82.
Mensa 1989 {published data only}
  • Mensa J, Moreno A, Segura F, Escofet C, Serrate G, Baga R, et al. Acute enteritis caused by Salmonella: effect of mecillinam and cotrimoxazol on the clinical course and fecal carrier state [Enteritis Aguda por Salmonella: influencia del mecillinam y del cotrimoxazol en el curso clinico y en el estado de portado fecal]. Medicina Clinica 1989;93(5):161-8.
Noguerado 1995 {published data only}
  • Noguerado A, Garcia-Polo I, Isasia T, Jimenez ML, Bermudez P, Pita J, et al. Early single dose therapy with ofloxacin for empirical treatment of acute gastroenteritis: a randomized, placebo-controlled double blind clinical trial. Journal of Antimicrobial Chemotherapy 1995;36(4):665-72.
Pichler 1986 {published data only}
Pichler 1987 {published data only}
  • Pichler HE, Diridl G, Stickler K, Wolf D. Clinical efficacy of ciprofloxacin compared with placebo in bacterial diarrhea. American Journal of Medicine 1987;82(4A):329-32.
Robins-Browne 1983 {published data only}
  • Robins-Browne RM, Coovadia HM, Bodasing MN, Mackenjee MK. Treatment of acute non-specific gastroenteritis of infants and young children with erythromycin. American Journal of Tropical Medicine and Hygiene 1983;32(4):886-90.
Sirinavin 2003 {published data only}
  • Sirinavin S, Thavornnunth J, Sakchainanont B, Bangtrakulnonth A, Chongthawonsatid S, Junumporn S. Norfloxacin and azithromycin for treatment of nontyphoidal Salmonella carriers. Clinical Infectious Diseases 2003;37(5):685-91.
Svenungsson 1990 {published data only}
  • Svenungsson B, Ekwall E, Hansson HB. Efficacy of the combination pivampicillin/pivmecillinam compared to placebo in the treatment of convalescent carriers of nontyphi Salmonella. Infection 1990;18(3):163-5.
Taylor 2006 {published and unpublished data}
  • Taylor DN, Bourgeois AL, Ericsson CD, Steffen R, Jiang ZD, Halpern J, et al. A randomized double blind, multicenter study of rifaximin compared with placebo and with ciprofloxacin in the treatment of travelers' diarrhea. American Journal of Tropical Medicine and Hygiene 2006;74(6):1060-66.
Wolfsdorf 1973 {published data only}

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Tsai 2012 {published and unpublished data}
  • Tsai MH. The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis. 2012.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Boyle 2007
Buchwald 1984
  • Buchwald DS, Blaser MJ. A review of human salmonellosis: II. Duration of excretion following infection with nontyphi Salmonella. Reviews of infectious Diseases 1984;6(3):345-56.
Chen 2007
Diez Dorado 2004
  • Díez Dorado R, Tagarro García A, Baquero-Artigao F, García-Miguel MJ, Uría González MJ, Peña García P, et al. Non-typhi Salmonella bacteremia in children: an 11-year review. Anales de Pediatría (Barcelona, Spain) 2004;60(4):344-8.
Effa 2011
  • Effa EE, Lassi ZS, Critchley JA, Garner P, Sinclair D, Olliaro PL, et al. Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). Cochrane Database of Systematic Reviews 2011, Issue 10. [DOI: 10.1002/14651858.CD004530.pub4]
Frost 1996
Gordon 2002
  • Gordon MA, Banda HT, Gondwe M, Gordon SB, Boeree MJ, Walsh AL, et al. Non-typhoidal salmonella bacteremia among HIV-infected Malawian adults: high mortality and frequent recrudescence. AIDS 2002;16(12):1633-41.
Graham 2002
  • Graham SM. Salmonellosis in children in developing and developed countries and populations. Current Opinion in Infectious Diseases 2002;15(5):507-12.
Hakanen 2006
  • Hakanen AJ, Kotilainen P, Pitkanen S, Huikko S, Siitonen A, Huovinen P. Reduction in fluoroquinolone susceptibility among non-typhoidal strains of Salmonella enterica isolated from Finnish patients. Journal of Antimicrobial Chemotherapy 2006;57(3):569-72.
Higgins 2011
  • Higgins JPT, Green S (editors). Chapter 6 Searching for studies Highly sensitive search strategies for identifying reports of randomized controlled trials in MEDLINE [Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011]. Available from www.cochrane-handbook.org.
Hohmann 2001
  • Hohmann EL. Nontyphoidal salmonellosis. Clinical Infectious Disease 2001;32(2):263-9.
Ispahani 2000
  • Ispahani P, Slack RC. Enteric fever and other extraintestinal salmonellosis in University Hospital Nottingham, UK, between 1980 and 1997. European Journal of Clinical Microbiology and Infectious Diseases 2000;19(9):679-87.
Jafari 2002
  • Jafari M, Forsberg J, Gilcher RO, Smith JW, Crutcher JM, McDermott M, et al. Salmonella sepsis caused by a platelet transfusion from a donor with a pet snake. New England Journal of Medicine 2002;347(14):1075-8.
Jertborn 1990
Kankwatira 2004
  • Kankwatira AM, Mwafulirwa GA, Gordon MA. Non-typhoidal salmonella bacteraemia-an under-recognized feature of AIDS in African subjects. Tropical Doctor 2004;34(4):198-200.
Kariuki 2006
  • Kariuki S, Revathi G, Kariuki N, Kiiru J, Mwituria J, Muyodi J, et al. Invasive multidrug-resistant nontyphoidal Salmonella infections in Africa: zoonotic or anthroponotic transmission?. Journal of Medical Microbiology 2006;55(Pt 5):585-91.
Kingsley 2009
  • Kingsley RA, Msefula CL, Thomson NR, Kariuki S, Holt KE, Gordon MA, et al. Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype. Genome Research 2009;19(12):2279-87.
Lin 2003
  • Lin TY, Chiu CH, Lin PY, Wang MH, Su LH, Lin TY. Short-term ceftriaxone therapy for treatment of severe non-typhoidal Salmonella enterocolitis. Acta Paediatrica 2003;92(5):537-40.
Mason 2000
  • Mason CJ, Longfield RN. Nontyphoidal Salmonella infections. In: Magill AJ, Laughlin LW editor(s). Hunter's Tropical Medicine and Emerging Infectious Diseases. 8th Edition. Philadelphia: W. B. Saunders, 2000:484-90.
MDH 2007
  • Minnesota Department of Health. Causes and symptoms of salmonellosis. www.health.state.mn.us/divs/idepc/diseases/salmonellosis/basics.html 20 November 2007 (accessed 2 April 2008).
Mead 1999
  • Mead PS, Slutsker L, Dietz V, McCaig LF, Bresee JS, Shapiro C, et al. Food-related illness and death in the United States. Emerging Infectious Diseases 1999;5(5):607-25.
Molbak 2002
  • Molbak K, Gerner-Smidt P, Wegener HC. Increasing quinolone resistance in Salmonella enterica serotype Enteritidis. Emerging Infectious Diseases 2002;8(5):514-5.
Morpeth 2009
Panhotra 2004
  • Panhotra BR, Saxena AK, Al-Ghamdi AM. Emerging nalidixic acid and ciprofloxacin resistance in non-typhoidal Salmonella isolated from patients having acute diarrhoeal disease. Annals of Saudi Medicine 2004;24(5):332-6.
Rabsch 2001
Reese 1991
  • Reese RE, Betts RF. Antibiotic use. In: Reese RE, Betts RF editor(s). A practical approach to Infectious diseases. 3rd Edition. Boston: Little Brown, 1991:821-1007.
Review Manager 5
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). 5.0. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2008.
Rowe 1997
  • Rowe B, Ward LR, Threlfall EJ. Multidrug-resistant Salmonella typhi: a worldwide epidemic. Clinical Infectious Disease 1997;24(Suppl 1):S106-9.
Vallenas 1985
  • Vallenas C, Hernandez H, Kay B, Black R, Gotuzzo E. Efficacy of bone marrow, blood, stool and duodenal contents cultures for bacteriologic confirmation of typhoid fever in children. Pediatric Infectious Diseases 1985;4(5):496-8.
Yee 2002
  • Yee CL, Duffy C, Gerbino PG, Stryker S, Noel GJ. Tendon or joint disorders in children after treatment with fluoroquinolones or azithromycin. Paediateric Infectious Disease Journal 2002;21(6):525-9.
Zapor 2005
  • Zapor M, Dooley DP. Salmonellosis. www.emedicine.com/med/topic2058.htm 2005 (accessed 14 September 2007).

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Sirinavin 2000
  • Sirinavin S, Garner P. Antibiotics for treating Salmonella gut infections. Cochrane Database of Systematic Reviews 2000, Issue 1. [DOI: 10.1002/14651858.CD001167]