Intervention Review

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Antimicrobial prophylaxis for colorectal surgery

  1. Richard L Nelson1,*,
  2. Ed Gladman2,
  3. Marija Barbateskovic3

Editorial Group: Cochrane Colorectal Cancer Group

Published Online: 9 MAY 2014

Assessed as up-to-date: 3 JUL 2013

DOI: 10.1002/14651858.CD001181.pub4


How to Cite

Nelson RL, Gladman E, Barbateskovic M. Antimicrobial prophylaxis for colorectal surgery. Cochrane Database of Systematic Reviews 2014, Issue 5. Art. No.: CD001181. DOI: 10.1002/14651858.CD001181.pub4.

Author Information

  1. 1

    Northern General Hospital, Department of General Surgery, Sheffield, Yorkshire, UK

  2. 2

    Northern General Hospital, Department of Surgery, Sheffield, S5 7AU, UK

  3. 3

    Bispebjerg Hospital, Cochrane Colorectal Cancer Group, Copenhagen, Denmark

*Richard L Nelson, Department of General Surgery, Northern General Hospital, Herries Road, Sheffield, Yorkshire, S5 7AU, UK. altohorn@btinternet.com. Rick.Nelson@sth.nhs.uk.

Publication History

  1. Publication Status: New search for studies and content updated (conclusions changed)
  2. Published Online: 9 MAY 2014

SEARCH

[Figure 1]
Figure 1. 'Risk of bias' summary: review authors' judgements about each risk of bias item for each included study.
[Figure 2]
Figure 2. 'Risk of bias' graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Antibiotic versus no antibiotic/placebo, Outcome 1 Surgical wound infection (SWI).
[Analysis 2.1]
Analysis 2.1. Comparison 2 Duration of therapy, Outcome 1 Surgical wound infection (SWI).
[Analysis 2.2]
Analysis 2.2. Comparison 2 Duration of therapy, Outcome 2 Surgical wound infection (SWI).
[Analysis 3.1]
Analysis 3.1. Comparison 3 Additional aerobic coverage, Outcome 1 Surgical wound infection (SWI).
[Analysis 4.1]
Analysis 4.1. Comparison 4 Additional anaerobic coverage, Outcome 1 Surgical wound infection (SWI).
[Analysis 5.1]
Analysis 5.1. Comparison 5 Aerobic versus anaerobic cover, Outcome 1 Surgical wound infection.
[Analysis 6.1]
Analysis 6.1. Comparison 6 Oral versus intravenous, Outcome 1 Surgical wound infection (SWI).
[Analysis 7.1]
Analysis 7.1. Comparison 7 Combined oral and intravenous versus oral or intravenous alone, Outcome 1 Surgical wound infection: oral + iv versus iv alone.
[Analysis 7.2]
Analysis 7.2. Comparison 7 Combined oral and intravenous versus oral or intravenous alone, Outcome 2 Surgical wound infection: combined oral and iv versus oral alone.
[Analysis 8.1]
Analysis 8.1. Comparison 8 Antibiotic given pre- or postoperatively, Outcome 1 Surgical wound infection.
[Analysis 9.1]
Analysis 9.1. Comparison 9 Antibiotic choice versus a gold standard, Outcome 1 Surgical wound infection (SWI).