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Intervention Review

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Vaccines for preventing influenza in healthy adults

  1. Tom Jefferson1,*,
  2. Carlo Di Pietrantonj2,
  3. Alessandro Rivetti2,
  4. Ghada A Bawazeer3,
  5. Lubna A Al-Ansary4,
  6. Eliana Ferroni5

Editorial Group: Cochrane Acute Respiratory Infections Group

Published Online: 7 JUL 2010

DOI: 10.1002/14651858.CD001269.pub4


How to Cite

Jefferson T, Di Pietrantonj C, Rivetti A, Bawazeer GA, Al-Ansary LA, Ferroni E. Vaccines for preventing influenza in healthy adults. Cochrane Database of Systematic Reviews 2010, Issue 7. Art. No.: CD001269. DOI: 10.1002/14651858.CD001269.pub4.

Author Information

  1. 1

    The Cochrane Collaboration, Roma, Italy

  2. 2

    Azienda Sanitaria Locale ASL AL, Servizio Regionale di Riferimento per l'Epidemiologia, SSEpi-SeREMI - Cochrane Vaccines Field, Alessandria, Piemonte, Italy

  3. 3

    King Saud University, Department of Clinical Pharmacy & KKUH, Riyadh, Saudi Arabia

  4. 4

    College of Medicine, King Saud University, Department of Family & Community Medicine, Holder of "Shaikh Abdullah S. Bahamdan" Research Chair for Evidence-Based Health Care and Knowledge Translation, Riyadh, Saudi Arabia

  5. 5

    Public Health Agency of Lazio Region, Infectious Diseases Unit, Rome, Italy

*Tom Jefferson, The Cochrane Collaboration, Via Puglie 23, Roma, 00187, Italy. jefferson.tom@gmail.com. jefferson@assr.it.

Publication History

  1. Publication Status: Edited (no change to conclusions), comment added to review
  2. Published Online: 7 JUL 2010

SEARCH

This is not the most recent version of the article. View current version (13 MAR 2014)

[Analysis 1.1]
Analysis 1.1. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 1 Influenza-like illness.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 2 Influenza.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 3 Physician visits.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 4 Days ill.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 5 Times any drugs were prescribed.
[Analysis 1.6]
Analysis 1.6. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 6 Times antibiotic was prescribed.
[Analysis 1.7]
Analysis 1.7. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 7 Working days lost.
[Analysis 1.8]
Analysis 1.8. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 8 Hospitalisations.
[Analysis 1.9]
Analysis 1.9. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 9 Pneumonia.
[Analysis 1.10]
Analysis 1.10. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 10 Clinical cases (clinically defined without clear definition).
[Analysis 1.11]
Analysis 1.11. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 11 Local harms.
[Analysis 1.12]
Analysis 1.12. Comparison 1 Inactivated parenteral vaccine versus placebo or do-nothing, Outcome 12 Systemic harms.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Live aerosol vaccine versus placebo or do-nothing, Outcome 1 Influenza-like illness.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Live aerosol vaccine versus placebo or do-nothing, Outcome 2 Influenza.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Live aerosol vaccine versus placebo or do-nothing, Outcome 3 Complications (bronchitis, otitis, pneumonia).
[Analysis 2.4]
Analysis 2.4. Comparison 2 Live aerosol vaccine versus placebo or do-nothing, Outcome 4 Influenza cases (clinically defined without clear definition).
[Analysis 2.5]
Analysis 2.5. Comparison 2 Live aerosol vaccine versus placebo or do-nothing, Outcome 5 Local harms.
[Analysis 2.6]
Analysis 2.6. Comparison 2 Live aerosol vaccine versus placebo or do-nothing, Outcome 6 Systemic harms.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Inactivated aerosol vaccine versus placebo or do-nothing, Outcome 1 Influenza-like illness.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Inactivated aerosol vaccine versus placebo or do-nothing, Outcome 2 Local harms.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Inactivated aerosol vaccine versus placebo or do-nothing, Outcome 3 Systemic harms.
[Analysis 4.1]
Analysis 4.1. Comparison 4 1968 to 1969 pandemic: inactivated polyvalent parenteral vaccine versus placebo, Outcome 1 Influenza-like illness.
[Analysis 4.2]
Analysis 4.2. Comparison 4 1968 to 1969 pandemic: inactivated polyvalent parenteral vaccine versus placebo, Outcome 2 Influenza.
[Analysis 4.3]
Analysis 4.3. Comparison 4 1968 to 1969 pandemic: inactivated polyvalent parenteral vaccine versus placebo, Outcome 3 Hospitalisations.
[Analysis 4.4]
Analysis 4.4. Comparison 4 1968 to 1969 pandemic: inactivated polyvalent parenteral vaccine versus placebo, Outcome 4 Pneumonia.
[Analysis 5.1]
Analysis 5.1. Comparison 5 1968 to 1969 pandemic: inactivated monovalent parenteral vaccine versus placebo, Outcome 1 Influenza-like illness.
[Analysis 5.2]
Analysis 5.2. Comparison 5 1968 to 1969 pandemic: inactivated monovalent parenteral vaccine versus placebo, Outcome 2 Influenza.
[Analysis 5.3]
Analysis 5.3. Comparison 5 1968 to 1969 pandemic: inactivated monovalent parenteral vaccine versus placebo, Outcome 3 Hospitalisations.
[Analysis 5.4]
Analysis 5.4. Comparison 5 1968 to 1969 pandemic: inactivated monovalent parenteral vaccine versus placebo, Outcome 4 Pneumonia.
[Analysis 5.5]
Analysis 5.5. Comparison 5 1968 to 1969 pandemic: inactivated monovalent parenteral vaccine versus placebo, Outcome 5 Working days lost.
[Analysis 5.6]
Analysis 5.6. Comparison 5 1968 to 1969 pandemic: inactivated monovalent parenteral vaccine versus placebo, Outcome 6 Days ill.
[Analysis 6.1]
Analysis 6.1. Comparison 6 1968 to 1969 pandemic: inactivated polyvalent aerosol vaccine versus placebo, Outcome 1 Influenza-like illness.
[Analysis 7.1]
Analysis 7.1. Comparison 7 1968 to 1969 pandemic: inactivated monovalent aerosol vaccine versus placebo, Outcome 1 Influenza-like illness.
[Analysis 8.1]
Analysis 8.1. Comparison 8 1968 to 1969 pandemic: live aerosol vaccine versus placebo, Outcome 1 Influenza cases (clinically defined without clear definition).
[Analysis 8.2]
Analysis 8.2. Comparison 8 1968 to 1969 pandemic: live aerosol vaccine versus placebo, Outcome 2 Complications (bronchitis, otitis, pneumonia).