Intervention Review

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Zinc for the common cold

  1. Meenu Singh1,*,
  2. Rashmi R Das2

Editorial Group: Cochrane Acute Respiratory Infections Group

Published Online: 18 JUN 2013

Assessed as up-to-date: 18 JAN 2013

DOI: 10.1002/14651858.CD001364.pub4

How to Cite

Singh M, Das RR. Zinc for the common cold. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD001364. DOI: 10.1002/14651858.CD001364.pub4.

Author Information

  1. 1

    Post Graduate Institute of Medical Education and Research, Department of Pediatrics, Chandigarh, India

  2. 2

    All India Institute of Medical Sciences, Department of Pediatrics, New Delhi, India

*Meenu Singh, Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India. meenusingh4@gmail.com. meenusingh@rediffmail.com.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 18 JUN 2013

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[Figure 1]
Figure 1. Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
[Figure 2]
Figure 2. Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
[Figure 3]
Figure 3. Forest plot of comparison: 1 Zinc versus placebo, outcome: 1.1 Duration of cold symptoms (in days).
[Figure 4]
Figure 4. Forest plot of comparison: 1 Zinc versus placebo, outcome: 1.1 Duration of cold symptoms (in days).
[Figure 5]
Figure 5. Forest plot of comparison: 1 Zinc versus placebo, outcome: 1.2 Severity of symptoms (score).
[Figure 6]
Figure 6. Forest plot of comparison: 1 Zinc versus placebo, outcome: 1.3 Incidence of common cold (IRR).
[Analysis 1.1]
Analysis 1.1. Comparison 1 Zinc versus placebo, Outcome 1 Duration of cold symptoms.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Zinc versus placebo, Outcome 2 Subgroup analysis (duration of cold symptoms).
[Analysis 1.3]
Analysis 1.3. Comparison 1 Zinc versus placebo, Outcome 3 Severity of cold symptoms.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Zinc versus placebo, Outcome 4 Subgroup analysis (severity of cold symptoms).
[Analysis 1.5]
Analysis 1.5. Comparison 1 Zinc versus placebo, Outcome 5 Incidence of common cold.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Zinc versus placebo, Outcome 1 Number of participants symptomatic after 3 days of treatment.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Zinc versus placebo, Outcome 2 Number of participants symptomatic after 5 days of treatment.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Zinc versus placebo, Outcome 3 Number of participants symptomatic after 7 days of treatment.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Zinc versus placebo, Outcome 4 Time to resolution of cough.
[Analysis 2.5]
Analysis 2.5. Comparison 2 Zinc versus placebo, Outcome 5 Time to resolution of nasal congestion.
[Analysis 2.6]
Analysis 2.6. Comparison 2 Zinc versus placebo, Outcome 6 Time to resolution of nasal drainage.
[Analysis 2.7]
Analysis 2.7. Comparison 2 Zinc versus placebo, Outcome 7 Time to resolution of sore throat.
[Analysis 2.8]
Analysis 2.8. Comparison 2 Zinc versus placebo, Outcome 8 Change in cough symptom score.
[Analysis 2.9]
Analysis 2.9. Comparison 2 Zinc versus placebo, Outcome 9 Change in nasal symptom score.
[Analysis 2.10]
Analysis 2.10. Comparison 2 Zinc versus placebo, Outcome 10 School absence (days).
[Analysis 2.11]
Analysis 2.11. Comparison 2 Zinc versus placebo, Outcome 11 Antibiotic use.
[Analysis 2.12]
Analysis 2.12. Comparison 2 Zinc versus placebo, Outcome 12 Any adverse event.
[Analysis 2.13]
Analysis 2.13. Comparison 2 Zinc versus placebo, Outcome 13 Bad taste.
[Analysis 2.14]
Analysis 2.14. Comparison 2 Zinc versus placebo, Outcome 14 Nausea.
[Analysis 2.15]
Analysis 2.15. Comparison 2 Zinc versus placebo, Outcome 15 Constipation.
[Analysis 2.16]
Analysis 2.16. Comparison 2 Zinc versus placebo, Outcome 16 Diarrhoea.
[Analysis 2.17]
Analysis 2.17. Comparison 2 Zinc versus placebo, Outcome 17 Abdominal pain.
[Analysis 2.18]
Analysis 2.18. Comparison 2 Zinc versus placebo, Outcome 18 Dry mouth.
[Analysis 2.19]
Analysis 2.19. Comparison 2 Zinc versus placebo, Outcome 19 Mouth irritation.