Intervention Review

Iron-chelating agents for treating malaria

  1. Helen J Smith1,*,
  2. Martin M Meremikwu2

Editorial Group: Cochrane Infectious Diseases Group

Published Online: 22 APR 2003

Assessed as up-to-date: 16 FEB 2003

DOI: 10.1002/14651858.CD001474

How to Cite

Smith HJ, Meremikwu MM. Iron-chelating agents for treating malaria. Cochrane Database of Systematic Reviews 2003, Issue 2. Art. No.: CD001474. DOI: 10.1002/14651858.CD001474.

Author Information

  1. 1

    Liverpool School of Tropical Medicine, International Health Group, Liverpool, Merseyside, UK

  2. 2

    University of Calabar Teaching Hospital, Department of Paediatrics, Calabar, Cross River State, Nigeria

*Helen J Smith, International Health Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, Merseyside, L3 5QA, UK.

Publication History

  1. Publication Status: Stable (no update expected for reasons given in 'What's new')
  2. Published Online: 22 APR 2003


Cited in:


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  1. 1
    Natasha Spottiswoode, Patrick E. Duffy, Hal Drakesmith, Iron, anemia and hepcidin in malaria, Frontiers in Pharmacology, 2014, 5,


  2. 2
    Richard J. Maude, Kamolrat Silamut, Katherine Plewes, Prakaykaew Charunwatthana, May Ho, M. Abul Faiz, Ridwanur Rahman, Md Amir Hossain, Mahtab U. Hassan, Emran Bin Yunus, Gofranul Hoque, Faridul Islam, Aniruddha Ghose, Josh Hanson, Joel Schlatter, Rachel Lacey, Alison Eastaugh, Joel Tarning, Sue J. Lee, Nicholas J. White, Kesinee Chotivanich, Nicholas P. J. Day, Arjen M. Dondorp, Randomized Controlled Trial of Levamisole Hydrochloride as Adjunctive Therapy in Severe Falciparum Malaria With High Parasitemia, The Journal of Infectious Diseases, 2014, 209, 1, 120


  3. 3
    P. Sonnet, C. Mullié, In vitro antimalarial activity of ICL670: A further proof of the correlation between inhibition of β-hematin formation and of peroxidative degradation of hemin, Experimental Parasitology, 2011, 128, 1, 26


  4. 4
    Frank Shann, Andrew C. Argent, Suchitra Ranjit, Pediatric Critical Care, 2011,


  5. 5
    Amber Glanfield, Donald P. McManus, Greg J. Anderson, Malcolm K. Jones, Pumping iron: a potential target for novel therapeutics against schistosomes, Trends in Parasitology, 2007, 23, 12, 583


  6. 6
    Geoffrey Pasvol, Management of severe malaria: interventions and controversies, Infectious Disease Clinics of North America, 2005, 19, 1, 211


  7. 7
    Jane Burch, Michael Eisenhut, How do iron-chelating agents affect outcomes in people being treated for malaria?, Cochrane Clinical Answers,
  8. 8
    Jane Burch, How do iron-chelating agents affect outcomes in people being treated for malaria?, Cochrane Clinical Answers,
  9. 9
    Helen J Smith, Martin M Meremikwu, Iron-chelating agents for treating malaria, The Cochrane Library,