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Tyrosine supplementation for phenylketonuria

  1. Diana Webster1,*,
  2. Joanne Wildgoose2

Editorial Group: Cochrane Cystic Fibrosis and Genetic Disorders Group

Published Online: 5 JUN 2013

Assessed as up-to-date: 1 MAY 2013

DOI: 10.1002/14651858.CD001507.pub3


How to Cite

Webster D, Wildgoose J. Tyrosine supplementation for phenylketonuria. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD001507. DOI: 10.1002/14651858.CD001507.pub3.

Author Information

  1. 1

    Bristol Royal Hospital for Children, Nutrition and Dietetic Department, Bristol, UK

  2. 2

    Bradford Royal Infirmary, Physio Corridor, Level 1, Bradford, UK

*Diana Webster, Nutrition and Dietetic Department, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, BS2 8BJ, UK. Diana.Webster@ubht.nhs.uk.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 5 JUN 2013

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[Analysis 1.1]
Analysis 1.1. Comparison 1 Tyrosine versus placebo (all participants), Outcome 1 Blood phenylalanine concentration (umol/l) (0-3 months).
[Analysis 1.2]
Analysis 1.2. Comparison 1 Tyrosine versus placebo (all participants), Outcome 2 Blood tyrosine concentration(umol/l) (0-3 months).
[Analysis 2.1]
Analysis 2.1. Comparison 2 Tyrosine versus placebo (continued on diet versus discontinued diet), Outcome 1 Blood phenylalanine concentration (umol/l) (0-3 months).
[Analysis 2.2]
Analysis 2.2. Comparison 2 Tyrosine versus placebo (continued on diet versus discontinued diet), Outcome 2 Blood tyrosine concentration (umol/l) (0-3 months).
[Analysis 2.5]
Analysis 2.5. Comparison 2 Tyrosine versus placebo (continued on diet versus discontinued diet), Outcome 5 Neuropsychological performance (0-3 months).