Intervention Protocol

Glucocorticosteroids for alcoholic hepatitis

  1. Humberto Saconato2,
  2. Christian Gluud1,
  3. Erik Christensen3,
  4. Álvaro N Atallah4

Editorial Group: Cochrane Hepato-Biliary Group

Published Online: 25 JAN 1999

DOI: 10.1002/14651858.CD001511

How to Cite

Saconato H, Gluud C, Christensen E, Atallah ÁN. Glucocorticosteroids for alcoholic hepatitis (Protocol). Cochrane Database of Systematic Reviews 1999, Issue 1. Art. No.: CD001511. DOI: 10.1002/14651858.CD001511.

Author Information

  1. 1

    Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 3344, Rigshospitalet, Copenhagen University Hospital, Cochrane Hepato-Biliary Group, Copenhagen, Denmark

  2. 2

    Federal University of Rio Grande do norte, Department of Medicine, São Paulo, Vila Clementino, Brazil

  3. 3

    Bispebjerg Hospital, Clinic of Internal Medicine I, Copenhagen, NV, Denmark

  4. 4

    Universidade Federal de São Paulo / Escola Paulista de Medicina, Brazilian Cochrane Centre, São Paulo, SP, Brazil

*Andrea Rambaldi, Cochrane Hepato-Biliary Group, Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 3344, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Copenhagen, DK-2100, Denmark. arambaldi@hotmail.com. rambaldi.andrea@libero.it.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 25 JAN 1999

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

The objectives are to:

A. Evaluate the efficacy of glucocorticosteroid intervention in patients with severe, clinically overt form of alcoholic hepatitis in terms of:
1. Mortality (primary end point).
2. Symptoms.
3. Liver biochemistry.

B. Identify possible predictive factors of a positive response.

C. Evaluate the incidence of adverse events of glucocorticosteroid intervention in these patients.