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Glucocorticosteroids for alcoholic hepatitis

  • Protocol
  • Intervention


Andrea Rambaldi, Cochrane Hepato-Biliary Group, Copenhagen Trial Unit, Centre for Clinical Intervention Research, Department 3344, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Copenhagen, DK-2100, Denmark.


This is the protocol for a review and there is no abstract. The objectives are as follows:

The objectives are to:

A. Evaluate the efficacy of glucocorticosteroid intervention in patients with severe, clinically overt form of alcoholic hepatitis in terms of:
1. Mortality (primary end point).
2. Symptoms.
3. Liver biochemistry.

B. Identify possible predictive factors of a positive response.

C. Evaluate the incidence of adverse events of glucocorticosteroid intervention in these patients.

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