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Intervention Review

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Sealants for preventing dental decay in the permanent teeth

  1. Anneli Ahovuo-Saloranta1,*,
  2. Helena Forss2,
  3. Tanya Walsh3,
  4. Anne Hiiri4,
  5. Anne Nordblad5,
  6. Marjukka Mäkelä6,
  7. Helen V Worthington7

Editorial Group: Cochrane Oral Health Group

Published Online: 28 MAR 2013

DOI: 10.1002/14651858.CD001830.pub4


How to Cite

Ahovuo-Saloranta A, Forss H, Walsh T, Hiiri A, Nordblad A, Mäkelä M, Worthington HV. Sealants for preventing dental decay in the permanent teeth. Cochrane Database of Systematic Reviews 2013, Issue 3. Art. No.: CD001830. DOI: 10.1002/14651858.CD001830.pub4.

Author Information

  1. 1

    National Institute for Health and Welfare / THL, Finnish Office for Health Technology Assessment / FinOHTA, Tampere, Finland

  2. 2

    Tampere University Hospital, Department of Oral and Dental Diseases, Tampere, Finland

  3. 3

    School of Dentistry, The University of Manchester, Manchester, UK

  4. 4

    City of Kotka, Department of Health Care, Kotka, Finland

  5. 5

    Ministry of Social Affairs and Health, Health Department, Helsinki, Finland

  6. 6

    National Institute for Health and Welfare / THL, Finnish Office for Health Technology Assessment / FinOHTA, Helsinki, Finland

  7. 7

    School of Dentistry, The University of Manchester, Cochrane Oral Health Group, Manchester, UK

*Anneli Ahovuo-Saloranta, Finnish Office for Health Technology Assessment / FinOHTA, National Institute for Health and Welfare / THL, Finn-Medi 3, Biokatu 10, Tampere, FI-33520, Finland. anneli.ahovuo-saloranta@thl.fi.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 28 MAR 2013

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This is not the most recent version of the article. View current version (31 JUL 2017)

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Amin 2008 {published data only}
  • Amin HE. Clinical and antibacterial effectiveness of three different sealant materials. Journal of Dental Hygiene 2008;82(5):45.
Arrow 1995 {published data only}
Barja-Fidalgo 2009 {published and unpublished data}
  • Barja-Fidalgo F, Maroun S, de Oliveira BH. Effectiveness of a glass ionomer cement used as a pit and fissure sealant in recently erupted permanent first molars. Journal of Dentistry for Children 2009;76(1):34-40.
Baseggio 2010 {published data only}
  • Baseggio W, Naufel FS, Davidoff DC, Nahsan FP, Flury S, Rodrigues JA. Caries-preventive efficacy and retention of a resin-modified glass ionomer cement and a resin-based fissure sealant: a 3-year split-mouth randomised clinical trial. Oral Health & Preventive Dentistry 2010;8(3):261-8.
Beiruti 2006 {published and unpublished data}
  • Beiruti N, Frencken JE, van't Hof MA, Taifour D, van Palenstein Helderman WH. Caries-preventive effect of a one-time application of composite resin and glass ionomer sealants after 5 years. Caries Research 2006;40(1):52-9.
Bojanini 1976 {published data only}
  • Bojanini J, Garces H, McCune RJ, Pineda A. Effectiveness of pit and fissure sealants in the prevention of caries. Journal of Preventive Dentistry 1976;3(6):31-4.
  • McCune RJ, Bojanini J, Abodeely RA. Effectiveness of a pit and fissure sealant in the prevention of caries: three-year clinical results. Journal of the American Dental Association 1979;99(4):619-23.
Bravo 2005 {published and unpublished data}
Brooks 1979 {published data only}
  • Brooks JD, Mertz-Fairhurst EJ, Della-Giustina VE, Fairhurst CW, Williams JE. A comparative study of the retention of two pit and fissure sealants: one-year results. Journal of Preventive Dentistry 1976;3(5):43-6.
  • Brooks JD, Mertz-Fairhurst EJ, Della-Giustina VE, Williams JE, Fairhurst CW. A comparative study of two pit and fissure sealants: three-year results in Augusta, Ga. Journal of the American Dental Association 1979;99(1):42-6.
  • Brooks JD, Mertz-Fairhurst EJ, Della-Giustina VE, Williams JE, Fairhurst CW. A comparative study of two pit and fissure sealants: two-year results in Augusta, Ga. Journal of the American Dental Association 1979;98(5):722-5.
  • Mertz-Fairhurst EJ, Della-Giustina VE, Brooks JE, Williams JE, Fairhurst CW. A comparative study of two pit and fissure sealants: results after 4 1/2 years in Augusta,Ga. Journal of the American Dental Association 1981;103(2):235-8.
  • Mertz-Fairhurst EJ, Fairhurst CW, Williams JE, Della-Giustina VE, Brooks JD. A comparative clinical study of two pit and fissure sealants: 7-year results in Augusta, Ga. Journal of the American Dental Association 1984;109(2):252-5.
  • Mertz-Fairhurst EJ, Fairhurst CW, Williams JE, Della-Giustina VE, Brooks JD. A comparative clinical study of two pit and fissure sealants: six-year results in Augusta,Ga. Journal of the American Dental Association 1982;105(2):237-9.
Charbeneau 1979 {published data only}
Chen 2012 {published and unpublished data}
  • Chen X, Du M, Fan M, Mulder J, Huysmans MC, Frencken JE. Effectiveness of two new types of sealants: retention after 2 years. Clinical Oral Investigations 2012;16(5):1443-50.
  • Chen X, Du MQ, Fan MW, Mulder J, Huysmans MC, Frencken JE. Caries-preventive effect of sealants produced with altered glass-ionomer materials, after 2 years. Dental Materials 2012;28(5):554-60.
de Luca-Fraga 2001 {published data only}
  • de Luca-Fraga LR, Pimenta LA. Clinical evaluation of glass-ionomer/resin-based hybrid materials used as pit and fissure sealants. Quintessence International 2001;32(6):463-8.
Dhar 2012 {published and unpublished data}
  • Dhar V, Chen H. Evaluation of resin based and glass ionomer based sealants placed with or without tooth preparation - a two year clinical trial. Pediatric Dentistry 2012;34(1):46-50.
Erdoğan 1987 {published data only}
  • Erdoğan B, Alaçam T. Evaluation of a chemically polymerized pit and fissure sealant - results after 4, 5 years. Journal of Paediatric Dentistry 1987;3:11-3.
Forss 1998 {published and unpublished data}
Ganesh 2006 {published and unpublished data}
  • Ganesh M, Tandon S. Clinical evaluation of FUJI VII sealant material. The Journal of Clinical Pediatric Dentistry 2006;31(1):52-7.
Güngör 2004 {published and unpublished data}
  • Güngör HC, Altay N, Alpar R. Clinical evaluation of a polyacid-modified resin composite-based fissure sealant: two-year results. Operative Dentistry 2004;29(3):254-60.
Hunter 1988 {published data only}
  • Hunter PB. A study of pit and fissure sealing in the School Dental Service. New Zealand Dental Journal 1988;84(375):10-2.
Karlzén-Reuterving 1995 {published data only}
  • Karlzén-Reuterving G, van Dijken JW. A three-year follow-up of glass ionomer cement and resin fissure sealants. Journal of Dentistry for Children 1995;62(2):108-10.
Kervanto-Seppälä 2008 {published and unpublished data}
  • Kervanto-Seppälä S, Lavonius E, Pietilä I, Pitkäniemi J, Meurman J, Kerosuo E. Comparing the caries-preventive effect of two fissure sealing modalities in public health care: a single application of glass ionomer and a routine resin-based sealant programme. A randomized split-mouth clinical trial. International Journal of Paediatric Dentistry 2008;18(1):56-61.
Lampa 2004 {published data only}
  • Lampa E, Brechter A, van Dijken JW. Effect of a nonrinse conditioner on the durability of a polyacid-modified resin composite fissure sealant. Journal of Dentistry for Children 2004;71(2):152-7.
Liu 2012 {published and unpublished data}
Mills 1993 {published data only}
  • Mills RW, Ball IA. A clinical trial to evaluate the retention of a silver cermet-ionomer cement used as a fissure sealant. Operative Dentistry 1993;18(4):148-54.
Pardi 2005 {published and unpublished data}
  • Pardi V, Pereira AC, Ambrosano GMB, Meneghim MdeC. Clinical evaluation of three different materials used as pit and fissure sealant: 24-months results. Journal of Clinical Pediatric Dentistry 2005;29(2):133-8.
Poulsen 2001 {published and unpublished data}
Raadal 1996 {published data only}
  • Raadal M, Utkilen AB, Nilsen OL. Fissure sealing with a light-cured resin-reinforced glass-ionomer cement (Vitrebond) compared with a resin sealant. International Journal of Paediatric Dentistry 1996;6(4):235-9.
Reisbick 1982 {published data only}
  • Reisbick MH, Thanos CE, Berson RB, Goldstein CM. Benefit from sealants in a moderately fluoridated community. CDA Journal California Dental Association 1982;10(1):53-6.
Richardson 1978 {published data only}
  • Gibson GB, Richardson AS. Sticky fissure management. 30-month report. Journal of Canadian Dental Association 1980;46(4):255-8.
  • Gibson GB, Richardson AS, Waldman R. The effectiveness of a chemically polymerized sealant in preventing occlusal caries: five-year results. Pediatric Dentistry 1982;4(4):309-10.
  • Richardson AS, Gibson GB, Waldman R. Chemically polymerized sealant in preventing occlusal caries. Journal of Canadian Dental Association 1980;46(4):259-60.
  • Richardson AS, Gibson GB, Waldman R. The effectiveness of a chemically polymerized sealant: Four-year results. Pediatric Dentistry 1980;2(1):24-6.
  • Richardson AS, Waldman R, Gibson GB. The effectiveness of a chemically polymerized sealant in preventing occlusal caries: two year results. Journal of Canadian Dental Association 1978;44(6):269-72.
Rock 1978 {published data only}
Rock 1996 {published data only}
  • Rock WP, Foulkes EE, Perry H, Smith AJ. A comparative study of fluoride-releasing composite resin and glass ionomer materials used as fissure sealants. Journal of Dentistry 1996;24(4):275-80.
Sheykholeslam 1978 {published and unpublished data}
  • Houpt M, Shey Z. Clinical effectiveness of an autopolymerized fissure sealant (Delton) after thirty-three months. Pediatric Dentistry 1979;1(3):165-8.
  • Houpt M, Shey Z. The effectiveness of a fissure sealant after six years. Pediatric Dentistry 1983;5(2):104-6.
  • Houpt M, Sheykholeslam Z. The clinical effectiveness of Delton fissure sealant after one year. Journal of Dentistry for Children 1978;45(2):130-2.
  • Sheykholeslam Z, Houpt M. Clinical effectiveness of an autopolymerized fissure sealant after 2 years. Community Dentistry and Oral Epidemiology 1978;6(4):181-4.
Sipahier 1995 {published and unpublished data}
  • Sipahier M, Ulusu T. Glass-ionomer-silver-cermet cements applied as fissure sealants II. Clinical evaluation. Quintessence International 1995;26(1):43-8.
Songpaisan 1995 {published data only}
Tagliaferro 2011 {published and unpublished data}
  • Tagliaferro EP, Pardi V, Ambrosano GM, Meneghim Mde C, da Silva SR, Pereira AC. Occlusal caries prevention in high and low risk schoolchildren. A clinical trial. American Journal of Dentistry 2011;24(2):109-14.
Williams 1996 {published data only}
  • Williams B, Laxton L, Holt RD, Winter GB. Fissure sealants: a 4-year clinical trial comparing an experimental glass polyalkenoate cement with a bis glycidyl methacrylate resin used as fissure sealants. British Dental Journal 1996;180(3):104-8.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Andjelic 1991 {published data only}
  • Andjelic P, Vojinovic J, Tatic E, Pintaric J. Fissure sealants as primary preventive measures. Four-year evaluation in Stara Pazova [Fissurenversiegelungen als primäre Vorbeugungsmassnahme. Eine vierjährige Bewertungsstudie in Stara Pazova]. Oralprophylaxe 1991;13(1):3-10.
Aslanova 2003 {published data only}
  • Aslanova FK, Seyidbayov OS. Comparative effectiveness assessment of different prophylaxis methods of the second teeth caries. Azerbaijan Medical Journal 2003;4:59-62.
Azul 1990 {published data only}
  • Azul AM. Fissure sealants - 5 years of use [Selantes de fissura - 5 anos de utilizacao]. Revista Portuguesa de Estomatologia e Cirurgia Maxilofacial 1990;31(1):27-33.
Baglioni-Gouvea 2001 {published data only}
  • Baglioni-Gouvea ME, Puppin-Rontani RM, Komati SM, Centenaro RS. Clinical evaluation of the retention and efficacy of a resin-based sealant and a compomer in occlusal sealing. Journal of Dental Research 2001;80(April 2001 Issue 4):1036 (Abs No 299).
Boksman 1987 {published data only}
  • Boksman L, Gratton DR, McCutcheon E, Plotzke OB. Clinical evaluation of a glass ionomer cement as a fissure sealant. Quintessence International 1987;18(10):707-9.
Braga 2009 {published data only}
  • Braga MM, Mendes FM, De Benedetto MS, Imparato JC. Effect of silver diammine fluoride on incipient caries lesions in erupting permanent first molars: a pilot study. Journal of Dentistry for Children 2009;76(1):28-33.
Carlsson 1992 {published data only}
  • Carlsson Å, Jonsson Y, Svensson K, Stahl B, Twetman S. Pit and fissure sealing and mutans streptococci levels in saliva. American Journal of Dentistry 1992;5(5):280-2.
Carlsson 1997 {published data only}
  • Carlsson Å, Petersson M, Twetman S. 2-year clinical performance of a fluoride-containing fissure sealant in young schoolchildren at caries risk. American Journal of Dentistry 1997;10(3):115-9.
Centenaro 2001 {published data only}
  • Centenaro RS, Puppin-Rontani RM, Komati SM, Baglioni-Gouvea ME. Clinical evaluation of the retention of a resin-based sealant and a glass ionomer for pit and fissure sealing. Journal of Dental Research 2001;80(April 2001 Issue 4):1036 (Abs No 300).
De Puel 1983 {published data only}
  • de Puel PN, Brassesco MB, Edelberg M. Clinical behavior of pit and fissure sealants. Results after 36 months [Comportamiento clinico de un sellador de fosas y fisuras. Resultados a 36 meses]. Revista de la Asociacion Odontologica Argentina 1983;71(1):4,6.
Dogon 1995 {published data only}
  • Dogon IL, Ping FI, Liang LG. Three year results of an evaluation of a fluoride sealant. Journal of Dental Reseach 1995;74(Spec Iss):404 (Abs No 26).
Duggan 1987 {published data only}
  • Duggan G, Midda M. Clinical trial of a new fissure sealant. Journal of the International Association of Dentistry for Children 1987;18(2):17-20.
Flório 2001 {published and unpublished data}
  • Flório FM, Pereira AC, Meneghim MC, Ramacciato JC. Evaluation of non-invasive treatment applied to occlusal surfaces. Journal of Dentistry for Children 2001;68(5-6):326-31.
Helle 1975 {published data only}
  • Helle A. Two fissure sealants tested for retention and caries reduction in Finnish children. Proceedings of the Finnish Dental Society 1975;71(3):91-5.
Hepp 1990 {published and unpublished data}
  • Hepp K, Tarjan I, Bodoki I. Comparative study of the fissure sealants Concise and Delton [Összehadonlito vizsgalatok Concise es Delton barazdazaro anyaggal]. Fogorvosi Szemle 1990;83(11):337-9.
Hickel 1989 {published data only}
  • Hickel R, Voss A. Comparative studies on fissure sealing: composite versus Cermet cement [Vergleichende untersuchung über fissurenversiegelung: komposit versus Cermet-zement]. Deutsche Zahnärztliche Zeitschrift 1989;44(6):472-4.
Hotz 1978 {published and unpublished data}
  • Hotz P, Hofstetter HW, Rohrbach UJ. Fissure sealing combined with enamel fluoridation. Follow-up study 2 years after sealing [Fissurenversiegelung in kombination mit schmelzfluorierung. Nachkontrolle von zweijährigen versiegelungen]. Schweizerische Monatsschrift für Zahnheilkunde 1978;88(4):313-23.
Irmisch 1992 {published data only}
  • Irmisch B. Caries prophylaxis using fissure sealing [Kariesprophylaxe mittels fissurenversiegelung]. Deutsche Zahnärztliche Zeitschrift 1992;47(11):790-3.
Jeng-Fen Liu 2000 {published data only}
  • Jeng-Fen Liu. Fissure sealing with resin modified glass ionomer: A one-year clinical study. Pediatric Dentistry 2000;22(3):241.
Jodkowska 1984 {published data only}
  • Jodkowska E. 2-year clinical follow-up after application of Concise Enamel Bond System for sealing defects in the occluding surfaces of teeth [Dwuletnie obserwacje kliniczne po zastosowaniu materialu zlozonego Concise enamel bond system do uszczelnienia powierzchni zujacej zebow]. Czasopismo Stomatologiczne 1984;37(11):839-46.
  • Jodkowska E. Effectiveness of sealing measures on the chewing surface of permanent teeth in clinical evaluation. II: Caries reduction [Wirksamkeit von Versiegelungsmassnahmen der Kaufläche bleibender Zähne in klinischer Beurteilung II: Kariesreduction]. Stomatologie der DDR 1985;35(5):275-9.
Jodkowska 2008 {published data only}
Kamala 2008 {published data only}
Kawakami 1984 {published data only}
  • Kawakami S, Komatsu H, Matsuda K, Shimokobe H. Clinical trial of a new glass ionomer cement as a fissure sealant. Shikai Tenbo-Dental Outlook 1984;64(4):748-58.
Komatsu 1994 {published data only}
  • Komatsu H, Shimokobe H, Kawakami S, Yoshimura M. Caries-preventive effect of glass ionomer sealant reapplication: study presents three-year results. Journal of the American Dental Association 1994;125(5):543-9.
Li 2008 {published data only}
  • Li SF, Deng M, He GQ, Luo WN. Evaluating the effects of GcFuji II glass ionomer cement in pit and fissure enameloplasty sealant technique. Journal of Clinical Rehabilitative Tissue Engineering Research 2008;12(23):4457-60.
Louw 2002 {published data only}
  • Louw AJ. Effect of glass ionomer sealant on caries in erupting molars. Journal of Dental Research 2002;81(Spec Iss B, Divisional Abstracts):B-375 (Abs No 52).
Lovadino 1994 {published data only}
  • Lovadino JR, Marcondes Martins LR, Sartini Filho R, Brasil JR, Gardenal Meneguel MA. Evaluation, after one year, of two sealant materials: glass ionomer cement and composite sealant [Avaliacão de dois materiáis utilizados como selante oclusal: ionômero X compósito]. Revista da Associacão Paulista de Cirurgiões Dentistas 1994;48:1243-6.
Lusanandana 1986 {published data only}
  • Lusanandana S, Panyangarm R, Charoensupaya O. Retention and effectiveness of sealants on dental caries in a community program. Journal of the Dental Association of Thailand 1986;36(5):145-52.
Manau 1989 {published data only}
  • Manau C, Cuenca E, Salleras L. [Estudio de la eficiencia de un programa comunitario de sellados de fisuras en un grupo de escolares]. Archivos de Odonto-Estomatología Preventiva y Comunitaria 1989;1:63-7.
Mejàre 1990 {published data only}
Mel'nichenko 1994 {published data only}
  • Mel'nichenko EM, Tristen' KS. Experience in preventing dental caries in the children of a city with a low fluorine content in its water. Stomatologiia 1994;73(4):64-5.
Morgan 1998 {published data only}
Morrow 1997 {published data only}
  • Morrow TA, Christensen WG, Cordner CI, Hein DK, Smith SL, Christensen RP. 2-year clinical performance of 4 sealants. Journal of Dental Research 1997;76:191.
Noack 1997 {published data only}
  • Noack MJ, Noack CB. Early fissure sealing with a compomer in high caries risk children. Journal of Dental Research 1997;5 (Divisional Abstracts):1136 (Abs No 332).
Oba 2009 {published data only}
  • Oba AA, Dülgergil T, Sönmez IS, Doğan S. Comparison of caries prevention with glass ionomer and composite resin fissure sealants. Journal of the Formosan Medical Association 2009;108(11):844-8.
Ohmori 1976 {published data only}
  • Ohmori I, Kikuchi K, Masuhara E, Nakabayashi N, Tanaka S. Effect of the methyl methacrylate-tributylborane sealant in preventing occlusal caries. Bulletin of Tokyo Medical and Dental University 1976;23(3):149-55.
Oliveira 2008 {published data only}
  • Oliveira FS, da Silva SM, Machado MA, Bijella MF, Lima JE, Abdo RC. Resin-modified glass ionomer cement and a resin-based material as occlusal sealants: a longitudinal clinical performance. Journal of Dentistry for Children 2008;75(2):134-43.
Pereira 1999 {published and unpublished data}
  • Pardi V, Pereira AC, Mialhe FL, Meneghim MdeC, Ambrosano GM. A 5-year evaluation of two glass-ionomer cements used as fissure sealants. Community Dentistry and Oral Epidemiology 2003;31(5):386-91.
  • Pereira AC, Basting RT, Pinelli C, de Castro Meneghim M, Werner CW. Retention and caries prevention of Vitremer and Ketac-bond used as occlusal sealants. American Journal of Dentistry 1999;12(2):62-4.
  • Pereira AC, Pardi V, Basting RT, Menighim MdeC, Pinelli C, Ambrosano GM, et al. Clinical evaluation of glass ionomers used as fissure sealants: twenty-four-month results. Journal of Dentistry for Children 2001;68(3):168-74.
  • Pereira AC, Pardi V, Mialhe FL, Meneghim MdeC, Ambrosano GM. A 3-year clinical evaluation of glass-ionomer cements used as fissure sealants. American Journal of Dentistry 2003;16(1):23-7.
Petrovic 1996 {published data only}
  • Petrovic V, Vulovic M, Vulicevic ZR. Clinical evaluation of pit and fissure sealants (IADR Abstract). Journal of Dental Research 1996;75:287.
Poulsen 1979 {published data only}
Poulsen 2006 {published data only}
Prados-Atienza 2002 {published and unpublished data}
  • Hita Iglesias C, Prados Atienza MB, Bravo M, Prados Sánchez E, Muñoz Soto E, González Rodríguez MP. Impact of public preventive programmes on oral quality of life of 11 to 12-yr-old school students. Medicina Oral, Patología Oral y Cirugía Bucal 2007;12:E408-11.
  • Prados-Atienza MB, Bravo-Perez M, Muñoz-Soto E, González-Rodríguez MP, Prados-Sánchez E. Effectiveness of fissure sealant and fluoride varnish on different tooth surfaces: A 24-month field trial [Efectividad de selladores de fisuras más barniz de flúor en distintas superficies dentarias: ensayo de campo a 24 meses]. RCOE 2002;7(2):167-74.
Puppin-Rontani 2006 {published data only}
  • Puppin-Rontani RM, Baglioni-Gouvea ME, deGoes MF, Garcia-Godoy F. Compomer as a pit and fissure sealant: effectiveness and retention after 24 months. Journal of Dentistry for Children 2006;73(1):31-6.
Rajic 2000 {published data only}
  • Rajic Z, Gvozdanovic Z, Rajic-Mestrovic S, Bagic I. Preventive sealing of dental fissures with Heliosil: a two-year follow-up. Collegium Antropologicum 2000;24(1):151-5.
Simonsen 1980 {published data only}
Skrinjaric 2008 {published data only}
Smales 1996 {published data only}
Taifour 2003 {published data only}
Tanguy 1984 {published data only}
  • Tanguy R, Casanova F, Barnaud J. Prevention of tooth fissure caries using a sealing resin in the public health service [Prevention de la carie des sillons dentaires avec une resine de scellement en sante publique]. Revue d' Odonto-Stomatologie 1984;13(2):125-30.
Tapias Ledesma 2002 {published data only}
  • Tapias Ledesma MA, Jimenez-Garcia R, Lamas F, Gil de Miguel A. Effectiveness of fissure sealants in child population at high risk of caries [Efectividad de los selladores de fisuras en una población infantil con alto riesgo de presentar caries]. Atención Primaria 2002;30(3):150-6.
Thylstrup 1976 {published data only}
Tostes 1997 {published data only}
  • Tostes M. Prevention of pit and fissure caries in permanent molars using different fluoride materials [Prevenção de cárie de sulcos e fissuras em dentes permanentes com diferentes materiais contendo fluoreto]. Revista Brasileira de Odontologia 1997;54:368-71.
Valsecki 1992 {published data only}
  • Valsecki Jr A, Vertuan V. Retention and efficiency of an occlusal sealant associated with a topical application of fluoride. Journal of Dental Research 1992;71(4, April (Divisional Abstracts)):967 (Abs No 63).
Vieira 2000 {published data only}
  • Vieira RS, Almeida ICS, Martinhon C, Rodriques CO, Freitas SFT. A 36 months follow-up of glass ionomer and resin sealants. Journal of Dental Research 2000;79(Spec Iss IADR Abstracts):417 (Abs No 2190).
  • Vieira RS, Martinhon C, Rodriques C. A 36 month follow-up of glass ionomer and resin fissure sealant. International Journal of Paediatric Dentistry 1999;9(Suppl 1):45 (Abst No P2.12).
Vrbic 1983 {published and unpublished data}
  • Vrbic V. Five-year experience with fissure sealing. Quintessence International 1986;17:371-2.
  • Vrbic V. Retention of fissure sealant and caries reduction. Quintessence International 1983;14:421-4.
  • Vrbic V. Retention of fissure sealant and caries reduction [Obstojnost fisurnega zalitja in zmanjsanje kariesa]. Zobozdravstveni Vestnik 1982;37(3-4):51-9.
Wåhlin 1997 {published data only}
  • Wåhlin G. Fissure sealing with glass ionomer cement and resin-based material. A comparative clinical study [Fissurförsegling med glasjonomer respektive resinbaserat material. Jämförande klinisk studie]. Tandläkartidningen 1997;89(15):49-54.
Winkler 1996 {published data only}
  • Winkler MM, Deschepper EJ, Dean JA, Moore BK, Cochran MA, Ewoldsen N. Using a resin-modified glass ionomer as an occlusal sealant: a one-year clinical study. Journal of the American Dental Association 1996;127(10):1508-14.
Yakut 2006 {published data only}
  • Yakut N, Sönmez H. Resin composite sealant vs. polyacid-modified resin composite applied to post eruptive mature and immature molars: two year clinical study. The Journal of Clinical Pediatric Dentistry 2006;30(3):215-8.
Yildiz 2004 {published data only}
Yilmaz 2010 {published data only}
  • Yilmaz Y, Beldüz N, Eyüboğlu O. A two-year evaluation of four different fissure sealants. European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry 2010;11(2):88-92.
Yoshihara 2000 {published data only}
  • Yoshihara A, Sakuma S, Miyazaki H. A comparative study of glass ionomer and resin-based material used as fissure sealants on the first molars with incipient remineralization. Koku Eisei Gakkai Zasshi 2000;50(5):777-82.
Zhang 2003 {published data only}
  • Zhang YY, Zhang L, Shan H. Clinical observation of microfilled sealant for first molars in children. Shanghai Kou Qiang Yi Xue/Shanghai Journal of Stomatology 2003;12(4):297-9.
Zimmer 2009 {published data only}
  • Zimmer S, Strafela N, Bastendorf KD, Bartsch A, Lang H, Barthel CR. Clinical success rate of a resin modified glass ionomer cement fissure sealant in comparison to a bis-GMA sealant after three years [Klinische erfolgsraten von fissurenversiegelungen mit kompomer oder bis-GMA nach drei jahren]. Oralprophylaxe & Kinderzahnheilkunde 2009;31(1):8-12.

References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Antonson 2012 {published data only}
  • Antonson SA, Antonson DE, Brener S, Crutchfield J, Larumbe J, Michaud C, et al. Twenty-four month clinical evaluation of fissure sealants on partially erupted permanent first molars: glass ionomer versus resin-based sealant. Journal of the American Dental Association 2012;143(2):115-22.
Madléna 1993 {published data only}
  • Madléna M, Kincses S, Alberth M, Keszthelyi G. Short-term effectiveness of fissure sealants [Barazdazaras hatekonysaganak rövid tavu vizsgalata]. Fogorvosi Szemle 1993;86(1):15-21.
Markovic 2012 {published data only}
  • Marković D, Petrović B, Perić T, Blagojević D. Microleakage, adaptation ability and clinical efficacy of two fluoride releasing fissure sealants [Ispitivanje mikrocurenja, površinske adaptacije i kliničke efikasnosti dva zalivača fisura sa sposobnošću otpuštanja fluorida]. Vojnosanitetski Pregled 2012;69(4):320-5.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
NCT00674869 {published data only}
  • Effectiveness of pit and fissure sealants in the prevention of dental caries.. Ongoing study December 2004..

Additional references

  1. References to studies included in this review
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  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
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ADA 2003
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Azarpazhooh 2008
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Higgins 2011a
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Higgins 2011b
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Mejàre 2003
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Nicholson 2007
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References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. References to ongoing studies
  5. Additional references
  6. References to other published versions of this review
Ahovuo-Saloranta 1999
  • Ahovuo-Saloranta A, Hiiri A, Nordblad A, Mäkëla M, Murtomaa H. Pit and fissure sealants for preventing dental decay in the permanent teeth of children and adolescents. Cochrane Database of Systematic Reviews 1999, Issue 4. [DOI: 10.1002/14651858.CD001830]
Ahovuo-Saloranta 2004
  • Ahovuo-Saloranta A, Hiiri A, Nordblad A, Worthington H, Mäkelä M. Pit and fissure sealants for preventing dental decay in the permanent teeth of children and adolescents. Cochrane Database of Systematic Reviews 2004, Issue 3. [DOI: 10.1002/14651858.CD001830.pub2]
Ahovuo-Saloranta 2008