Benzodiazepines for generalised anxiety disorder (GAD)

  • Major change
  • Protocol
  • Intervention

Authors


Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

The objectives of this review are to assess the effects of any benzodiazepine for the treatment of generalised anxiety disorder (GAD) in participants from any setting.

  1. To investigate the efficacy and acceptability of benzodiazepines in the treatment of generalised anxiety disorder compared with placebo.

  2. To investigate the efficacy and acceptability of benzodiazepines compared with psychological treatments (cognitive behavioural therapy (CBT), applied relaxation combined or augmented, other).

  3. To investigate the efficacy and acceptability of benzodiazepines compared with other medications (antidepressants, azapirones, hydroxyzine, pregabalin, kava, antipsychotics (first generation and second generation) and others, including augmentation strategies).

  4. To investigate the efficacy and acceptability of benzodiazepines compared with other benzodiazepines.