Intervention Protocol

Benzodiazepines for generalised anxiety disorder (GAD)

  1. Christopher Gale1,*,
  2. G Peter Herbison2,
  3. Paul Glue1,
  4. John Coverdale3,
  5. Giuseppe Guaiana4

Editorial Group: Cochrane Depression, Anxiety and Neurosis Group

Published Online: 14 NOV 2012

DOI: 10.1002/14651858.CD001846.pub3


How to Cite

Gale C, Herbison GP, Glue P, Coverdale J, Guaiana G. Benzodiazepines for generalised anxiety disorder (GAD) (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 11. Art. No.: CD001846. DOI: 10.1002/14651858.CD001846.pub3.

Author Information

  1. 1

    University of Otago, Department of Psychological Medicine, Dunedin, New Zealand

  2. 2

    Dunedin School of Medicine, University of Otago, Department of Preventive & Social Medicine, Dunedin, New Zealand

  3. 3

    Baylor College of Medicine, Texas Medical Centre, Menninger Department of Psychiatry, Houston, Texas, USA

  4. 4

    University of Western Ontario, Department of Psychiatry, St Thomas, Ontario, Canada

*Christopher Gale, Department of Psychological Medicine, University of Otago, Dunedin School of Medicine, PO Box 913, Dunedin, 9010, New Zealand. chris.gale@otago.ac.nz.

Publication History

  1. Publication Status: Amended to reflect a change in scope (see 'What's new')
  2. Published Online: 14 NOV 2012

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Abstract

  1. Top of page
  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

The objectives of this review are to assess the effects of any benzodiazepine for the treatment of generalised anxiety disorder (GAD) in participants from any setting.

  1. To investigate the efficacy and acceptability of benzodiazepines in the treatment of generalised anxiety disorder compared with placebo.
  2. To investigate the efficacy and acceptability of benzodiazepines compared with psychological treatments (cognitive behavioural therapy (CBT), applied relaxation combined or augmented, other).
  3. To investigate the efficacy and acceptability of benzodiazepines compared with other medications (antidepressants, azapirones, hydroxyzine, pregabalin, kava, antipsychotics (first generation and second generation) and others, including augmentation strategies).
  4. To investigate the efficacy and acceptability of benzodiazepines compared with other benzodiazepines.