Antibiotics for trachoma

doi:10.1002/14651858.CD001860.pub3

Intervention Review

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Antibiotics for trachoma

Jennifer R Evans^*,
Anthony W Solomon

Editorial Group: Cochrane Eyes and Vision Group

Published Online: 16 MAR 2011

Assessed as up-to-date: 11 DEC 2010

DOI: 10.1002/14651858.CD001860.pub3

Database Title

The Cochrane Library

Additional Information

How to Cite

Evans JR, Solomon AW. Antibiotics for trachoma. Cochrane Database of Systematic Reviews 2011, Issue 3. Art. No.: CD001860. DOI: 10.1002/14651858.CD001860.pub3.

Author Information

London School of Hygiene & Tropical Medicine, Cochrane Eyes and Vision Group, ICEH, London, UK

^*Jennifer R Evans, Cochrane Eyes and Vision Group, ICEH, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. jennifer.evans@lshtm.ac.uk.

Publication History

Publication Status: New search for studies and content updated (conclusions changed)
Published Online: 16 MAR 2011

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	Figure 1. Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.
	Figure 2. Methodological quality summary: review authors' judgements about each methodological quality item for each included study.
	Analysis 1.1. Comparison 1 Any antibiotic versus control (individuals), Outcome 1 Active trachoma at three months.
	Analysis 1.2. Comparison 1 Any antibiotic versus control (individuals), Outcome 2 Ocular C.trachomatis infection at three months.
	Analysis 1.3. Comparison 1 Any antibiotic versus control (individuals), Outcome 3 Active trachoma at 12 months.
	Analysis 1.4. Comparison 1 Any antibiotic versus control (individuals), Outcome 4 Ocular C. trachomatis infection at 12 months.
	Analysis 2.1. Comparison 2 Subgroup analysis: oral and topical antibiotics versus control (individuals), Outcome 1 Active trachoma at three months.
	Analysis 2.2. Comparison 2 Subgroup analysis: oral and topical antibiotics versus control (individuals), Outcome 2 Ocular C. trachomatis infection at three months.
	Analysis 2.3. Comparison 2 Subgroup analysis: oral and topical antibiotics versus control (individuals), Outcome 3 Active trachoma at 12 months.
	Analysis 2.4. Comparison 2 Subgroup analysis: oral and topical antibiotics versus control (individuals), Outcome 4 Ocular C. trachomatis infection at 12 months.
	Analysis 3.1. Comparison 3 Oral versus topical antibiotics (individuals), Outcome 1 Active trachoma at three months.
	Analysis 3.2. Comparison 3 Oral versus topical antibiotics (individuals), Outcome 2 Ocular C. trachomatis infection at three months.
	Analysis 3.3. Comparison 3 Oral versus topical antibiotics (individuals), Outcome 3 Active trachoma at 12 months.
	Analysis 3.4. Comparison 3 Oral versus topical antibiotics (individuals), Outcome 4 Ocular C. trachomatis infection at 12 months.
	Analysis 4.1. Comparison 4 Oral azithromycin versus topical tetracycline (individuals), Outcome 1 Active trachoma at three months.
	Analysis 4.2. Comparison 4 Oral azithromycin versus topical tetracycline (individuals), Outcome 2 Ocular C. trachomatis infection at three months.
	Analysis 4.3. Comparison 4 Oral azithromycin versus topical tetracycline (individuals), Outcome 3 Active trachoma at 12 months.
	Analysis 4.4. Comparison 4 Oral azithromycin versus topical tetracycline (individuals), Outcome 4 Ocular C. trachomatis infection at 12 months.
	Analysis 5.1. Comparison 5 Oral azithromycin versus control (communities), Outcome 1 Active trachoma at 12 months.
	Analysis 5.2. Comparison 5 Oral azithromycin versus control (communities), Outcome 2 Ocular C. trachomatis infection at 12 months.
	Analysis 6.1. Comparison 6 Oral azithromycin versus topical tetracycline (communities), Outcome 1 Active trachoma at 3 months.
	Analysis 6.2. Comparison 6 Oral azithromycin versus topical tetracycline (communities), Outcome 2 Ocular C. trachomatis infection at 3 months.
	Analysis 6.3. Comparison 6 Oral azithromycin versus topical tetracycline (communities), Outcome 3 Active trachoma at 12 months.
	Analysis 6.4. Comparison 6 Oral azithromycin versus topical tetracycline (communities), Outcome 4 Ocular C. trachomatis infection at 12 months.