Intervention Review
Laser resurfacing for facial acne scars
Editorial Group: Cochrane Skin Group
Published Online: 8 JUL 2009
Assessed as up-to-date: 13 MAR 2000
DOI: 10.1002/14651858.CD001866
Copyright © 2009 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Database Title
Additional Information
How to Cite
Jordan R, Cummins CCL, Burls A, Seukeran DDC. Laser resurfacing for facial acne scars. Cochrane Database of Systematic Reviews 2000, Issue 3. Art. No.: CD001866. DOI: 10.1002/14651858.CD001866.
Publication History
- Publication Status: Edited (no change to conclusions)
- Published Online: 8 JUL 2009
- Abstract
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- Cited By
Abstract
Background
Most people have acne at some stage during their life, with about one per cent being left with permanent acne scars. Recent laser techniques are thought to be more effective than chemical peels and dermabrasion.
Objectives
To assess the effects of laser resurfacing for treating facial acne scars.
Search methods
We searched MEDLINE (1966 to April 1999), EMBASE (1980 to April 1999), Science Citation Index (1981 to April 1999), the Cochrane Controlled Trials Register (April 1999), DARE (April 1999), INAHTA (April 1999), NHS HTA Internet site (April 1999). Dermatological Surgery (1995 to March 1999) and the British Journal of Dermatology (1995 to September 1999) were handsearched. We searched the reference lists of relevant articles and contacted experts and commercial laser manufacturers.
Selection criteria
Randomised controlled trials which compare different laser resurfacing techniques for treating patients with facial acne scars, or compare laser resurfacing with other resurfacing techniques or no treatment.
Data collection and analysis
Two reviewers independently selected studies, assessed the quality of studies and extracted data.
Main results
No randomised controlled trials where laser treatment was compared to either placebo or a different type of laser were found. Most of the 27 studies uncovered were poor quality case series with small numbers of acne-scarred patients.
Authors' conclusions
The lack of good quality evidence does not enable any conclusions to be drawn about the effectiveness of lasers for treating atrophic or ice-pick acne scars. Well designed randomised controlled comparisons of carbon dioxide versus Erbium:YAG laser are urgently needed.
Plain language summary
Laser treatment for acne scars
Acne (acne vulgaris) is caused by a combination of excess skin oil, bacteria and other tissue leading to blockage of the pores. Inflamed spots usually appear on the face, chest, shoulders or upper arms. Permanent physical scarring may result. Treatment of scars includes using steroids, chemical and mechanical resurfacing techniques (such as dermabrasion), or surgery to fill the scarred area with fat, skin or collagen. Laser resurfacing has the potential to be more precise than other techniques in the treatment of some facial scars, but is expensive and may have adverse effects. The review found no trials of laser resurfacing. There is not enough evidence to show whether laser resurfacing is worthwhile for acne scars.
摘要
背景
以雷射磨皮治療臉部青春痘疤痕
大部份人在一生中某個階段都會長青春痘,其中約1% 的人會留有色素性痘疤。新的雷射科技被認為比化學換膚或傳統磨皮更為有效
目標
評估雷射磨皮對於臉部痘疤的治療效果
搜尋策略
我們搜尋MEDLINE (1966年到1999四月), EMBASE (1980年到1999四月), Science Citation Index (1981年到1999四月), Cochrane Controlled Trials Register (1999年四月), DARE (1999年四月), INAHTA (1999年四月), NHS HTA Internet site (1999年四月) ,Dermatological Surgery (1995年到1999三月) 以及the British Journal of Dermatology (1995年到1999年九月) 。我們查詢相關參考文獻並與專家和雷射製造廠商連絡。
選擇標準
在有臉部痘疤的病人,比較不同雷射磨皮的方式,或是雷射磨皮和其他磨皮,或是雷射磨皮和無治療的隨機對照試驗。
資料收集與分析
兩位審查員獨立地選擇試驗,評估其品質和資料。
主要結論
沒有找到比較不同雷射治療或和安慰劑比較的隨機對照試驗。在我們找到的27個試驗當中大部分是品質不好、個案數少的痘疤病人報告。
作者結論
由於缺乏好的証據,雷射治療對於萎縮性或是冰錐性痘疤的治療成效是無法下任何結論的。我們急需一個設計良好的,比較二氧化碳雷射和鉺雅鉻雷射的隨機對照試驗。
翻譯人
本摘要由馬偕醫院黃政傑翻譯。
此翻譯計畫由臺灣國家衛生研究院 (National Health Research Institutes, Taiwan) 統籌。
總結
雷射治療對於痘疤並沒有足夠的証據顯示有效。青春痘是由多方面原因造成,包括皮膚油脂、細菌、以及其他阻塞毛孔的組織。發炎性班點通常出現在臉上,胸前,肩膀,或是上臂。可能會造成永久性的疤痕。疤痕的治療包括使用類固醇,化學或是物理性磨皮,或是手術以脂肪、皮膚、或膠原蛋白填充。雷射治療比起其他治療能夠更精準地治療某些臉部疤痕,但是比較昂貴而且也可能有副作用。本回顧發現沒有雷射磨皮的相關隨機對照試驗。
