Intervention Review

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Antibiotics for treating scrub typhus

  1. Qin Liu2,
  2. Ratana Panpanich1,*

Editorial Group: Cochrane Infectious Diseases Group

Published Online: 22 JUL 2002

Assessed as up-to-date: 25 MAY 2010

DOI: 10.1002/14651858.CD002150


How to Cite

Liu Q, Panpanich R. Antibiotics for treating scrub typhus. Cochrane Database of Systematic Reviews 2002, Issue 3. Art. No.: CD002150. DOI: 10.1002/14651858.CD002150.

Author Information

  1. 1

    Faculty of Medicine, Community Medicine, Chiang Mai, North, Thailand

  2. 2

    School of Public Health, Chongqing Medical University, Effective Healthcare Research Programme Consortium China (Chongqing) RPC Programme, Chongqing, China

*Ratana Panpanich, Community Medicine, Faculty of Medicine, Chiang Mai University, 110 Intawaroros, Chiang Mai, North, 50200, Thailand. rpanpani@mail.med.cmu.ac.th.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 22 JUL 2002

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[Figure 1]
Figure 1. Forest plot of comparison: 1 Tetracycline vs chloramphenicol, outcome: 1.1 Febrile after 48 hours.
[Figure 2]
Figure 2. Forest plot of comparison: 2 Doxycycline vs tetracycline, outcome: 2.1 Febrile after 48 hours.
[Figure 3]
Figure 3. Forest plot of comparison: 3 Rifampicin vs doxycycline, outcome: 3.1 Febrile after 48 hours.
[Figure 4]
Figure 4. Forest plot of comparison: 6 Azithromycin vs doxycycline, outcome: 6.1 Febrile after 48 hours.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Tetracycline vs chloramphenicol, Outcome 1 Febrile after 48 hours.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Tetracycline vs chloramphenicol, Outcome 2 Relapse.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Doxycycline vs tetracycline, Outcome 1 Febrile after 48 hours.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Doxycycline vs tetracycline, Outcome 2 Relapse.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Doxycycline vs tetracycline, Outcome 3 Duration of fever.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Doxycycline vs tetracycline, Outcome 4 Treatment failure.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Rifampicin vs doxycycline, Outcome 1 Febrile after 48 hours.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Rifampicin vs doxycycline, Outcome 2 Relapse.
[Analysis 4.1]
Analysis 4.1. Comparison 4 High rifampicin dose vs standard rifampicin dose, Outcome 1 Febrile after 48 hours.
[Analysis 4.2]
Analysis 4.2. Comparison 4 High rifampicin dose vs standard rifampicin dose, Outcome 2 Relapse.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Doxycycline vs standard rifampicin dose vs high rifampicin dose, Outcome 1 Number of participants febrile after 48 hours.
[Analysis 5.2]
Analysis 5.2. Comparison 5 Doxycycline vs standard rifampicin dose vs high rifampicin dose, Outcome 2 Median fever clearance time (hours).
[Analysis 5.3]
Analysis 5.3. Comparison 5 Doxycycline vs standard rifampicin dose vs high rifampicin dose, Outcome 3 Number of participants with a relapse.
[Analysis 6.1]
Analysis 6.1. Comparison 6 Azithromycin vs doxycycline, Outcome 1 Febrile after 48 hours.
[Analysis 6.2]
Analysis 6.2. Comparison 6 Azithromycin vs doxycycline, Outcome 2 Relapse.
[Analysis 6.3]
Analysis 6.3. Comparison 6 Azithromycin vs doxycycline, Outcome 3 Gastrointestinal side effect.
[Analysis 6.4]
Analysis 6.4. Comparison 6 Azithromycin vs doxycycline, Outcome 4 Treatment failure.
[Analysis 7.1]
Analysis 7.1. Comparison 7 Telithromycin vs doxycycline, Outcome 1 Duration of fever.
[Analysis 7.2]
Analysis 7.2. Comparison 7 Telithromycin vs doxycycline, Outcome 2 Failure.
[Analysis 7.3]
Analysis 7.3. Comparison 7 Telithromycin vs doxycycline, Outcome 3 Relapse.
[Analysis 7.4]
Analysis 7.4. Comparison 7 Telithromycin vs doxycycline, Outcome 4 Adverse effects.
[Analysis 7.5]
Analysis 7.5. Comparison 7 Telithromycin vs doxycycline, Outcome 5 Gastrointestinal side effects.