The increasing popularity of complementary and alternative medicine appears to be particularly evident amongst people with chronic diseases. In the treatment of osteoarthritis, one therapy that has been identified as having potential benefit is plant and herbal medicine (phytotherapy).
To determine the effectiveness of herbal therapies in treating osteoarthritis.
Databases for mainstream and complementary medicine were searched using terms to include all forms of arthritis combined with herbal medicine. We searched the following electronic databases: Cochrane Musculoskeletal Group register, Cochrane Complementary Medicine Field register, Cochrane Controlled Trials Register (CCTR), MEDLINE, EMBASE, CISCOM, AMED, CINAHL, Dissertation Abstracts and BIDS ISI. We also searched the reference lists from retrieved trials.
All randomized trials of herbal interventions in osteoarthritis, compared to placebo. Studies were included according to an a priori protocol and agreement was reached between two reviewers who independently read each selected paper for content and assessment of quality. Papers of any language were included.
Data collection and analysis
Data were extracted independently by the same two reviewers.
Five studies (four different herbal interventions) met the review criteria. Two studies were suitable for data pooling. It was not possible to draw firm conclusions from the single studies but the two combined studies of avocado/soybean unsaponifiables showed beneficial effects on functional index, pain, intake of non-steroidal anti-inflammatory drugs (NSAIDs) and global evaluation. No serious side effects were reported.
The evidence for avocado-soybean unsaponifiables in the treatment of osteoarthritis is convincing but evidence for the other herbal interventions is insufficient to either recommend or discourage their use.
搜尋包括Cochrane Musculoskeletal Group register, Cochrane Complementary Medicine Field register, Cochrane Controlled Trials Register (CCTR), MEDLINE, EMBASE, CISCOM, AMED, CINAHL, Dissertation Abstracts and BIDS ISI，同時搜尋所選文章之參考文獻。
此翻譯計畫由臺灣國家衛生研究院(National Health Research Institutes, Taiwan)統籌。
大豆未皂化物(Avocado soybean unsaponifiables)對退化性關節炎病患有幫助。關節炎情形時常發生，而某些人可能日趨嚴重而造成失能。一般認為傳統的治療方式的副作用讓人感到不適，因此使得補充療法與另類療法被廣為使用。本回顧的目標為評估治療退化性關節炎的中草藥的證據。在兩個研究當中，大豆未皂化物(ASU)的顯示可能有效果，有待進一步的研究來驗證其功效。其他治療方式的單一研究顯示無法確定柳樹皮製劑(Reumalex)、局部使用辣椒素，以及tipi茶的效果。