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Intervention Review

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Probiotics for treating infectious diarrhoea

  1. Stephen J Allen1,*,
  2. B Okoko2,
  3. Elizabeth G Martinez3,
  4. Germana V Gregorio3,
  5. Leonila F Dans4

Editorial Group: Cochrane Infectious Diseases Group

Published Online: 21 JAN 2009

Assessed as up-to-date: 19 JUN 2003

DOI: 10.1002/14651858.CD003048.pub2

Database Title

Additional Information

How to Cite

Allen SJ, Okoko B, Martinez EG, Gregorio GV, Dans LF. Probiotics for treating infectious diarrhoea. Cochrane Database of Systematic Reviews 2003, Issue 4. Art. No.: CD003048. DOI: 10.1002/14651858.CD003048.pub2.

Author Information

  1. 1

    Swansea University, School of Medicine, Swansea, West Glamorgan, UK

  2. 2

    Medical Research Council Laboratories, Banjul, Gambia

  3. 3

    College of Medicine-Philippine General Hospital, University of the Philippines, Department of Pediatrics, Manila, National Capital Region, Philippines

  4. 4

    Philippine General Hospital, University of the Philippines, Department of Pediatrics and Clinical Epidemiology, Manila, National Capital Region, Philippines

*Stephen J Allen, School of Medicine, Swansea University, Room 314, The Grove Building, Singleton Park, Swansea, West Glamorgan, SA2 8PP, UK. S.J.Allen@swansea.ac.uk.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 21 JAN 2009

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[Analysis 1.1]
Analysis 1.1. Comparison 1 Probiotic versus control, Outcome 1 Diarrhoea lasting 3 or more days.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Probiotic versus control, Outcome 2 Diarrhoea lasting 4 or more days.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Probiotic versus control, Outcome 3 Mean duration of diarrhoea (hours).
[Analysis 1.4]
Analysis 1.4. Comparison 1 Probiotic versus control, Outcome 4 Mean stool frequency on day 2.
[Analysis 1.5]
Analysis 1.5. Comparison 1 Probiotic versus control, Outcome 5 Mean stool frequency on day 3.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Sensitivity analysis; diarrhoea lasting 3 or more days, Outcome 1 Generation of allocation sequence.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Sensitivity analysis; diarrhoea lasting 3 or more days, Outcome 2 Allocation concealment.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Sensitivity analysis; diarrhoea lasting 3 or more days, Outcome 3 Blinding.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Sensitivity analysis; diarrhoea lasting 3 or more days, Outcome 4 Follow up.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Sensitivity analysis: diarrhoea lasting 4 or more days, Outcome 1 Generation of allocation sequence.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Sensitivity analysis: diarrhoea lasting 4 or more days, Outcome 2 Allocation concealment.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Sensitivity analysis: diarrhoea lasting 4 or more days, Outcome 3 Blinding.
[Analysis 3.4]
Analysis 3.4. Comparison 3 Sensitivity analysis: diarrhoea lasting 4 or more days, Outcome 4 Follow up.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Sensitivity analysis; mean duration of diarrhoea (hours), Outcome 1 Generation of allocation sequence.
[Analysis 4.2]
Analysis 4.2. Comparison 4 Sensitivity analysis; mean duration of diarrhoea (hours), Outcome 2 Allocation concealment.
[Analysis 4.3]
Analysis 4.3. Comparison 4 Sensitivity analysis; mean duration of diarrhoea (hours), Outcome 3 Blinding.
[Analysis 4.4]
Analysis 4.4. Comparison 4 Sensitivity analysis; mean duration of diarrhoea (hours), Outcome 4 Follow up.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Children with rotavirus diarrhoea, Outcome 1 Mean duration of diarrhoea (hours).
[Analysis 6.1]
Analysis 6.1. Comparison 6 Mortality stratum for children and adults in the countries where trials were undertaken (children/adults), Outcome 1 Diarrhoea lasting 3 or more days.
[Analysis 6.2]
Analysis 6.2. Comparison 6 Mortality stratum for children and adults in the countries where trials were undertaken (children/adults), Outcome 2 Diarrhoea lasting 4 or more days.
[Analysis 6.3]
Analysis 6.3. Comparison 6 Mortality stratum for children and adults in the countries where trials were undertaken (children/adults), Outcome 3 Mean duration of diarrhoea (hours).
[Analysis 6.4]
Analysis 6.4. Comparison 6 Mortality stratum for children and adults in the countries where trials were undertaken (children/adults), Outcome 4 Mean stool frequency on day 2.
[Analysis 6.5]
Analysis 6.5. Comparison 6 Mortality stratum for children and adults in the countries where trials were undertaken (children/adults), Outcome 5 Mean stool frequency on day 3.
[Analysis 7.1]
Analysis 7.1. Comparison 7 Age of participants, Outcome 1 Diarrhoea lasting 3 or more days.
[Analysis 7.2]
Analysis 7.2. Comparison 7 Age of participants, Outcome 2 Diarrhoea lasting 4 or more days.
[Analysis 7.3]
Analysis 7.3. Comparison 7 Age of participants, Outcome 3 Mean stool frequency on day 2.
[Analysis 7.4]
Analysis 7.4. Comparison 7 Age of participants, Outcome 4 Mean stool frequency on day 3.
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