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Probiotics for treating acute infectious diarrhoea

  1. Stephen J Allen1,*,
  2. Elizabeth G Martinez2,
  3. Germana V Gregorio2,
  4. Leonila F Dans3

Editorial Group: Cochrane Infectious Diseases Group

Published Online: 10 NOV 2010

Assessed as up-to-date: 10 AUG 2010

DOI: 10.1002/14651858.CD003048.pub3


How to Cite

Allen SJ, Martinez EG, Gregorio GV, Dans LF. Probiotics for treating acute infectious diarrhoea. Cochrane Database of Systematic Reviews 2010, Issue 11. Art. No.: CD003048. DOI: 10.1002/14651858.CD003048.pub3.

Author Information

  1. 1

    Swansea University, School of Medicine, Swansea, West Glamorgan, UK

  2. 2

    University of the Philippines College of Medicine, Department of Pediatrics, Manila, National Capital Region, Philippines

  3. 3

    University of the Philippines College of Medicine, Departments of Pediatrics and Clinical Epidemiology, Manila, National Capital Region, Philippines

*Stephen J Allen, School of Medicine, Swansea University, Room 314, The Grove Building, Singleton Park, Swansea, West Glamorgan, SA2 8PP, UK. S.J.Allen@swansea.ac.uk.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 10 NOV 2010

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[Figure 1]
Figure 1. Funnel plot of comparison: 1 Primary diarrhoea outcomes, outcome: 1.1 Mean duration of diarrhoea.
[Figure 2]
Figure 2. Funnel plot of comparison: 1 Primary diarrhoea outcomes, outcome: 1.2 Diarrhoea lasting ≥ 4 days.
[Figure 3]
Figure 3. Funnel plot of comparison: 1 Primary diarrhoea outcomes, outcome: 1.3 Mean stool frequency on day 2.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Primary diarrhoea outcomes, Outcome 1 Mean duration of diarrhoea.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Primary diarrhoea outcomes, Outcome 2 Diarrhoea lasting ≥4 days.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Primary diarrhoea outcomes, Outcome 3 Mean stool frequency on day 2.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Secondary diarrhoea outcomes, Outcome 1 Diarrhoea lasting ≥3 days.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Secondary diarrhoea outcomes, Outcome 2 Mean stool frequency on day 3.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Strain of probiotic organisms, Outcome 1 Mean duration of diarrhoea.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Strain of probiotic organisms, Outcome 2 Diarrhoea lasting ≥4 days.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Strain of probiotic organisms, Outcome 3 Mean stool frequency on day 2.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Single organism versus combinations, Outcome 1 Mean duration of diarrhoea.
[Analysis 4.2]
Analysis 4.2. Comparison 4 Single organism versus combinations, Outcome 2 Diarrhoea lasting ≥4 days.
[Analysis 4.3]
Analysis 4.3. Comparison 4 Single organism versus combinations, Outcome 3 Mean stool frequency on day 2.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Live versus killed organisms, Outcome 1 Mean duration of diarrhoea.
[Analysis 6.1]
Analysis 6.1. Comparison 6 Dose of probiotic; live organisms, Outcome 1 Mean duration of diarrhoea.
[Analysis 6.2]
Analysis 6.2. Comparison 6 Dose of probiotic; live organisms, Outcome 2 Diarrhoea lasting ≥4 days.
[Analysis 6.3]
Analysis 6.3. Comparison 6 Dose of probiotic; live organisms, Outcome 3 Mean stool frequency on day 2.
[Analysis 7.1]
Analysis 7.1. Comparison 7 Children with rotavirus diarrhoea, Outcome 1 Mean duration of diarrhoea.
[Analysis 7.2]
Analysis 7.2. Comparison 7 Children with rotavirus diarrhoea, Outcome 2 Mean stool frequency on day 2.
[Analysis 8.1]
Analysis 8.1. Comparison 8 Severity of diarrhoea; studies of outpatients, Outcome 1 Mean duration of diarrhoea.
[Analysis 9.1]
Analysis 9.1. Comparison 9 Mortality stratum for children and adults in the countries where trials were undertaken (children/adults), Outcome 1 Mean duration of diarrhoea.
[Analysis 9.2]
Analysis 9.2. Comparison 9 Mortality stratum for children and adults in the countries where trials were undertaken (children/adults), Outcome 2 Diarrhoea lasting ≥4 days.
[Analysis 9.3]
Analysis 9.3. Comparison 9 Mortality stratum for children and adults in the countries where trials were undertaken (children/adults), Outcome 3 Mean stool frequency on day 2.