Intervention Review

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Prophylactic antibiotics for preventing Gram positive infections associated with long-term central venous catheters in oncology patients

  1. Marianne D van de Wetering1,*,
  2. Job BM van Woensel2,
  3. Theresa A Lawrie3

Editorial Group: Cochrane Gynaecological, Neuro-oncology and Orphan Cancer Group

Published Online: 25 NOV 2013

Assessed as up-to-date: 28 JUN 2013

DOI: 10.1002/14651858.CD003295.pub3


How to Cite

van de Wetering MD, van Woensel JBM, Lawrie TA. Prophylactic antibiotics for preventing Gram positive infections associated with long-term central venous catheters in oncology patients. Cochrane Database of Systematic Reviews 2013, Issue 11. Art. No.: CD003295. DOI: 10.1002/14651858.CD003295.pub3.

Author Information

  1. 1

    Emma Children's Hospital/Academic Medical Center, Department of Paediatric Oncology, Amsterdam, Netherlands

  2. 2

    Emma Children's Hospital / Academic Medical Centre, Pediatrics, Amsterdam, Netherlands

  3. 3

    Royal United Hospital, Cochrane Gynaecological, Neuro-oncology and Orphan Cancer Group, Bath, UK

*Marianne D van de Wetering, Department of Paediatric Oncology, Emma Children's Hospital/Academic Medical Center, PO Box 22660, Amsterdam, 1100 DD, Netherlands. m.d.vandewetering@amc.uva.nl.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 25 NOV 2013

SEARCH

[Figure 1]
Figure 1. Study flow diagram of updated (June 2013) search.
[Figure 2]
Figure 2. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Figure 3]
Figure 3. Funnel plot of comparison: 2 Antibiotic and heparin flush or lock solution versus heparin only, outcome: 2.1 Catheter-related sepsis.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Antibiotics prior to long-term CVC insertion versus control, Outcome 1 Catheter-related sepsis.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Antibiotic and heparin flush or lock solution versus heparin only, Outcome 1 Catheter-related sepsis.