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Lung lavage for meconium aspiration syndrome in newborn infants

  1. Seokyung Hahn1,*,
  2. Hyun Jin Choi2,
  3. Roger Soll3,
  4. Peter A. Dargaville4

Editorial Group: Cochrane Neonatal Group

Published Online: 30 APR 2013

Assessed as up-to-date: 15 FEB 2013

DOI: 10.1002/14651858.CD003486.pub2


How to Cite

Hahn S, Choi HJ, Soll R, Dargaville PA. Lung lavage for meconium aspiration syndrome in newborn infants. Cochrane Database of Systematic Reviews 2013, Issue 4. Art. No.: CD003486. DOI: 10.1002/14651858.CD003486.pub2.

Author Information

  1. 1

    Seoul National University College of Medicine, Department of Medicine, Seoul, Korea, South

  2. 2

    Seoul National University College of Medicine, Department of Preventive Medicine, Seoul, Korea, South

  3. 3

    University of Vermont, Division of Neonatal-Perinatal Medicine, Burlington, Vermont, USA

  4. 4

    Royal Hobart Hospital, Department of Paediatrics, Hobart, Tasmania, Australia

*Seokyung Hahn, Department of Medicine, Seoul National University College of Medicine, 28 Yongon-dong Chongno-gu, Seoul, 110-744, Korea, South. hahns@snu.ac.kr.

Publication History

  1. Publication Status: New
  2. Published Online: 30 APR 2013

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Dargaville 2011 {published data only}
  • Dargaville PA, Copnell B, Mills JF, Haron I, Lee JK, Tingay DG, et al. Randomized controlled trial of lung lavage with dilute surfactant for meconium aspiration syndrome. Journal of Pediatrics 2011;158(3):383-9.
Gadzinowski 2008 {published data only}
  • Gadzinowski J, Kowalska K, Vidyasagar D. Treatment of MAS with PPHN using combined therapy: SLL, bolus surfactant and iNO. Journal of Perinatology 2008;28(Suppl 3):S56-66.
Wiswell 2002 {published data only}
  • Wiswell TE, Knight GR, Finer NN, Donn SM, Desai H, Walsh WF, et al. A multicenter, randomized, controlled trial comparing Surfaxin (Lucinactant) lavage with standard care for treatment of meconium aspiration syndrome. Pediatrics 2002;109(6):1081-7.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Armenta 2011 {published data only}
  • Armenta JMV, Urbina EC, Herrera JC. Surfactant bronchial lavage in meconium aspiration syndrome: A comparative study. Intensive Care Medicine 2011;37:S317.
Burke-Strickland 1973 {published data only}
  • Burke-Strickland M, Edwards NB. Meconium aspiration in the newborn. Minnesota Medicine 1973;56:1031-5.
Carson 1976 {published data only}
  • Carson BS, Losey RW, Bowes WAJ, Simmons MA. Combined obstetric and pediatric approach to prevent meconium aspiration syndrome. American Journal of Obstetrics and Gynecology 1976;126(6):712-5.
Chang 2003 {published data only}
  • Chang HY, Hsu CH, Kao HA, Hung HY, Chang JH, Peng CC, et al. Treatment of severe meconium aspiration syndrome with dilute surfactant lavage. Journal of the Formosan Medical Association 2003;102(5):326-30.
Dargaville 2007 {published and unpublished data}
Kowalska 2002 {published data only}
  • Kowalska K, Szymankiewicz M, Gadzinowski J. An effectiveness of surfactant lung lavage (SLL) in meconium aspiration syndrome (MAS) [Skutecznosc plukania drzewa tchawiczo-oskrzelowego roztworem naturalnego surfaktantu (SLL) w leczeniu zespolu aspiracji smolki (MAS) - doniesienie wstepne]. Przeglad Lekarski. 2002; Vol. 59 Suppl 1:21-4.
Lam 1999 {published data only}
Ogawa 1997 {published data only}
  • Ogawa Y. Bronchial lavage with surfactant solution for the treatment of meconium aspiration syndrome. Hot Topics in Neonatology Conference Book. Chicago: Ross Laboratories, 1997:259-64.
Rosegger 1987 {published data only}
  • Rosegger H, Engele H, Haas J. Tracheobronchial lavage-a supplementary measure in the initial management of meconium aspiration syndrome [Tracheobronchiallavage-eine ergänzende Maßnahme zur erstversorgung beim mekoniumaspirationssyndrom]. Wiener Klinische Wochenschrift 1987;99(24):843-7.
Salvia-Roigés 2004 {published data only}
Schlösser 2002 {published data only}
  • Schlössser RL, Veldman A, Fischer D, Allendorf A, von Loewenich V. Lavage with exogenous surfactant in neonatal meconium aspiration syndrome [Lavage mit exogenem surfactant bei neonataler mekoniumaspiration]. Zeitschrift für Geburtshilfe und Neonatologie. 2002;206(1):15-8.
Su 1998 {published data only}
  • Su BH, Hu PS, Peng CT, Tsai CH. The effect of bronchial lavage and surfactant supplement on severe meconium aspiration syndrome. Mid-Taiwan Journal of Medicine 1998;3:191-7.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
McNamara 2006 {unpublished data only}
  • McNamara P. Surfactant lavage vs. Bolus surfactant in neonates with meconium aspiration. ClinicalTrials.gov (http://www.clinicaltrials.gov/ct2/show/NCT00312507?term=McNamara&rank=1) (accessed 19.02.2013).
Segal 2012 {unpublished data only}
  • Wiswell TE. Phase III randomized study of lucinactant in full term newborn infants with meconium aspiration syndrome. ClinicalTrials.gov (http://clinicaltrials.gov/show/NCT00004500) (accessed 19.02.2013).
Sur-Lu-Lav 2011 {unpublished data only}
  • Nangia S. Comparison of surfactant lung lavage with standard care in the treatment of meconium aspiration syndrome (Sur-Lu-Lav). ClinicalTrials.gov(http://clinicaltrials.gov/ct2/show/NCT01310621?term=Sur-Lu-Lav&rank=1) (accessed 19.02.2013).

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
Chinese Collaborative Study Group 2005
  • Chinese Collaborative Study Group for Neonatal respiratory Diseases. Treatment of severe meconium aspiration syndrome with porcine surfactant: a multicentre, randomized, controlled trial. Acta Paediatrica 2005;94(7):896-902.
Choi 2012
  • Choi HJ, Hahn S, Lee J, Park BJ, Lee SM, Kim HS, et al. Surfactant lavage therapy for meconium aspiration syndrome: a systematic review and meta-analysis. Neonatology 2012;101(3):183-91.
Cochrane 1998
  • Cochrane CG, Revak SD, Merritt TA, Schraufstatter IU, Hoch RC, Henderson C, et al. Bronchoalveolar lavage with KL4-surfactant in models of meconium aspiration syndrome. Pediatric Research 1998;44(5):705-15.
Dargaville 2001
Dargaville 2003
  • Dargaville PA, Mills JF, Headley BM, Chan Y, Coleman L, Loughnan PM, et al. Therapeutic lung lavage in the piglet model of meconium aspiration syndrome. American Journal of Respiratory and Critical Care Medicine 2003;168(4):456-63.
Dargaville 2008
El Shahed 2007
Findlay 1996
Fuchimukai 1987
Higgins 2011
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Ibara 1995
  • Ibara S, Ikenoue T, Murata Y, Sakamoto H, Saito T, Nakamura Y, et al. Management of meconium aspiration syndrome by tracheobronchial lavage and replacement of Surfactant-TA. Acta Paediatrica Japonica 1995;37(1):64-7.
Lotze 1998
  • Lotze A, Mitchell BR, Bulas DI, Zola EM, Shalwitz RA, Gunkel JH, et al. Multicenter study of surfactant (beractant) use in the treatment of term infants with severe respiratory failure. Journal of Pediatrics 1998;132(1):40-7.
Marraro 1998
  • Marraro G, Bonati M, Ferrari A, Barzaghi MM, Pagani C, Bortolotti A, et al. Perfluorocarbon broncho-alveolar lavage and liquid ventilation versus saline broncho-alveolar lavage in adult guinea pig experimental model of meconium inhalation. Intensive Care Med 1998;24(5):501-8.
Maturana 2005
  • Maturana A, Torres-Pereyra J, Salinas R, Astudillo P, Moya FR, The Chile Surf Group. A randomized trial of natural surfactant for moderate to severe meconium aspiration syndrome. PAS. 2005; Vol. 57:1545.
Mosca 1996
  • Mosca F, Colnaghi M, Castoldi F. Lung lavage with a saline volume similar to functional residual capacity followed by surfactant administration in newborns with severe meconium aspiration syndrome. Intensive Care Med 1996;22(12):1412-3.
Moses 1991
Ohama 1994
  • Ohama Y, Itakura Y, Koyama N, Eguchi H, Ogawa Y. Effect of surfactant lavage in a rabbit model of meconium aspiration syndrome. Acta Paediatrica Japonica 1994;36(3):236-8.
Ohama 1999
Paranka 1992
RevMan 2011 [Computer program]
  • The Nordic Cochrane Centre. The Cochrane Collaboration. Review Manager (RevMan). Version 5.2. Copenhagan: The Nordic Cochrane Centre. The Cochrane Collaboration, 2011.
Tran 1980
Tyler 1978
Wiswell 1993
Wiswell 2000
  • Wiswell TE, Gannon CM, Jacob J, Goldsmith L, Szyld E, Weiss K, et al. Delivery room management of the apparently vigorous meconium-stained neonate: results of the multicenter, international collaborative trial. Pediatrics 2000;105(1 Pt 1):1-7.