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Non-steroidal anti-inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults

  1. Porjai Pattanittum1,
  2. Tari Turner2,
  3. Sally Green2,
  4. Rachelle Buchbinder3,*

Editorial Group: Cochrane Musculoskeletal Group

Published Online: 31 MAY 2013

Assessed as up-to-date: 11 OCT 2012

DOI: 10.1002/14651858.CD003686.pub2


How to Cite

Pattanittum P, Turner T, Green S, Buchbinder R. Non-steroidal anti-inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults. Cochrane Database of Systematic Reviews 2013, Issue 5. Art. No.: CD003686. DOI: 10.1002/14651858.CD003686.pub2.

Author Information

  1. 1

    Faculty of Public Health, Khon Kaen University, Department of Biostatistics and Demography, Khon Kaen, Khon Kaen, Thailand

  2. 2

    Monash University, School of Public Health & Preventive Medicine, Melbourne, Victoria, Australia

  3. 3

    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Monash Department of Clinical Epidemiology at Cabrini Hospital, Malvern, Victoria, Australia

*Rachelle Buchbinder, Monash Department of Clinical Epidemiology at Cabrini Hospital, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Suite 41, Cabrini Medical Centre, 183 Wattletree Road, Malvern, Victoria, 3144, Australia. rachelle.buchbinder@monash.edu.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 31 MAY 2013

SEARCH

[Figure 1]
Figure 1. Results of screening for studies that met inclusion criteria.
[Figure 2]
Figure 2. Risk of bias across all trials: review authors' judgements for each risk of bias item presented as percentages across all included trials.
[Figure 3]
Figure 3. Risk of bias summary: review authors' judgements about each risk of bias item for each included trial.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Topical NSAIDs versus placebo, Outcome 1 Pain at endpoint of study (10 days to 4 weeks) on 10cm VAS (10=maximum pain).
[Analysis 1.2]
Analysis 1.2. Comparison 1 Topical NSAIDs versus placebo, Outcome 2 Treatment success (proportion reporting fair, good or excellent overall effectiveness of treatment) at 28 days (14 days of therapy).
[Analysis 1.3]
Analysis 1.3. Comparison 1 Topical NSAIDs versus placebo, Outcome 3 Adverse events.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Topical NSAID versus leech therapy, Outcome 1 Overall pain (0 to 300mm VAS).
[Analysis 2.2]
Analysis 2.2. Comparison 2 Topical NSAID versus leech therapy, Outcome 2 DASH.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Topical NSAID versus leech therapy, Outcome 3 Quality of life- physical.
[Analysis 2.4]
Analysis 2.4. Comparison 2 Topical NSAID versus leech therapy, Outcome 4 Maximum peak grip strength.
[Analysis 2.5]
Analysis 2.5. Comparison 2 Topical NSAID versus leech therapy, Outcome 5 Adverse events- local skin reaction.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Oral NSAIDs versus placebo, Outcome 1 Improvement in pain (100mm vertical VAS) at endpoint of study (28 days).
[Analysis 3.2]
Analysis 3.2. Comparison 3 Oral NSAIDs versus placebo, Outcome 2 Improvement in function (100mm vertical VAS at endpoint of study (28 days).
[Analysis 3.3]
Analysis 3.3. Comparison 3 Oral NSAIDs versus placebo, Outcome 3 Improvement in pain-free maximum grip strength (kg) at endpoint of study (28 days).
[Analysis 3.4]
Analysis 3.4. Comparison 3 Oral NSAIDs versus placebo, Outcome 4 Treatment success (complete recovery or improved) at 4 weeks.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Oral NSAIDs versus glucocorticoid injection, Outcome 1 Treatment success (complete recovery or improved) at 2 or 4 weeks.
[Analysis 4.2]
Analysis 4.2. Comparison 4 Oral NSAIDs versus glucocorticoid injection, Outcome 2 Change in grip strength (kPa).
[Analysis 5.1]
Analysis 5.1. Comparison 5 Oral NSAIDs versus vasodilator, Outcome 1 Pain (0 to 10 VAS).
[Analysis 6.1]
Analysis 6.1. Comparison 6 Oral Diflusinal versus oral Naproxen, Outcome 1 Treatment success defined as no remaining symptoms or improved at 2 weeks.
[Analysis 6.2]
Analysis 6.2. Comparison 6 Oral Diflusinal versus oral Naproxen, Outcome 2 Treatment success defined as excellent, very good or good overall pain relief at 2 weeks.
[Analysis 6.3]
Analysis 6.3. Comparison 6 Oral Diflusinal versus oral Naproxen, Outcome 3 Number of participants experiencing any adverse effects.