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Partial liquid ventilation for preventing death and morbidity in adults with acute lung injury and acute respiratory distress syndrome

  1. Imelda M Galvin1,*,
  2. Andrew Steel2,
  3. Ruxandra Pinto3,
  4. Niall D Ferguson4,
  5. Mark W Davies5

Editorial Group: Cochrane Anaesthesia, Critical and Emergency Care Group

Published Online: 22 JUL 2013

Assessed as up-to-date: 12 NOV 2012

DOI: 10.1002/14651858.CD003707.pub3


How to Cite

Galvin IM, Steel A, Pinto R, Ferguson ND, Davies MW. Partial liquid ventilation for preventing death and morbidity in adults with acute lung injury and acute respiratory distress syndrome. Cochrane Database of Systematic Reviews 2013, Issue 7. Art. No.: CD003707. DOI: 10.1002/14651858.CD003707.pub3.

Author Information

  1. 1

    Queen's University, Kingston, Ontario, Canada

  2. 2

    University of Toronto, Department of Anesthesiology and Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada

  3. 3

    Sunnybrook, Critical Care Medicine, Toronto, Ontario, Canada

  4. 4

    University Health Network and Mount Sinai Hospital, University of Toronto, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada

  5. 5

    Department of Paediatrics & Child Health, The University of Queensland, Grantley Stable Neonatal Unit, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia

*Imelda M Galvin, Queen's University, Kingston, Ontario, Canada. galvini@KGH.KARI.NET.

Publication History

  1. Publication Status: New search for studies and content updated (conclusions changed)
  2. Published Online: 22 JUL 2013

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.

Other bias-bias resulting from imbalance in baseline prognostic variables and competing interests.
[Figure 3]
Figure 3. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.

Other bias-bias resulting from imbalance in baseline prognostic variables and competing interests.
[Figure 4]
Figure 4. Forest plot of comparison 1. 28 day mortality, PLV versus CMV Outcome:28 Day Mortality.
[Figure 5]
Figure 5. Forest plot of comparison 2.1. Ventilator-Free Days - PLV versus CMV - Outcome: Days Free of Mechanical Ventilation at Day 28.
[Figure 6]
Figure 6. Forest plot of comparison 3.4. Adverse Events - Outcome: Bradycardia.
[Analysis 1.1]
Analysis 1.1. Comparison 1 28 day mortality - PLV versus CMV, Outcome 1 28 Day Mortality.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Ventilator Free Days - PLV versus CMV, Outcome 1 Days Free of Mechanical Ventilation at Day 28.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Adverse Events, Outcome 1 Hypoxia.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Adverse Events, Outcome 2 Pneumothorax.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Adverse Events, Outcome 3 Hypotension.
[Analysis 3.4]
Analysis 3.4. Comparison 3 Adverse Events, Outcome 4 Bradycardia.
[Analysis 3.5]
Analysis 3.5. Comparison 3 Adverse Events, Outcome 5 Cardiac Arrest.