Azathioprine treatment for multiple sclerosis

  • Protocol
  • Intervention



This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

The objective of this review is to assess the efficacy and safety of Aza treatment in patients with MS.
The primary questions are whether oral administration of Aza :

  • decreases the frequency of relapses in relapsing-remitting MS

  • increases the probability to remain free from relapses after starting therapy

  • decreases the progression of disability

  • is a safe treatment

Secondary questions are whether oral administration of Aza:

  • reduces the need of steroid treatments

  • reduces the need of hospitalisation