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Steroids for idiopathic sudden sensorineural hearing loss

  1. Benjamin PC Wei1,2,
  2. Dimitra Stathopoulos1,
  3. Stephen O'Leary1,*

Editorial Group: Cochrane Ear, Nose and Throat Disorders Group

Published Online: 2 JUL 2013

Assessed as up-to-date: 22 APR 2013

DOI: 10.1002/14651858.CD003998.pub3


How to Cite

Wei BPC, Stathopoulos D, O'Leary S. Steroids for idiopathic sudden sensorineural hearing loss. Cochrane Database of Systematic Reviews 2013, Issue 7. Art. No.: CD003998. DOI: 10.1002/14651858.CD003998.pub3.

Author Information

  1. 1

    Royal Victorian Eye and Ear Hospital/University of Melbourne, Department of Otolaryngology, Melbourne, Victoria 3002, Australia

  2. 2

    Royal Victorian Eye and Ear Hospital/University of Melbourne, Department of Surgery, Melbourne, Australia

*Stephen O'Leary, Department of Otolaryngology, Royal Victorian Eye and Ear Hospital/University of Melbourne, 32 Gisborne Street, Melbourne, Victoria 3002, Australia. sjoleary@unimelb.edu.au.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 2 JUL 2013

SEARCH

[Analysis 1.1]
Analysis 1.1. Comparison 1 Oral steroid versus oral placebo immediately post-treatment, Outcome 1 Hearing recovery: average speech frequencies (500, 1000, 2000 Hz).
[Analysis 1.2]
Analysis 1.2. Comparison 1 Oral steroid versus oral placebo immediately post-treatment, Outcome 2 Hearing improvement: average hearing level at six frequencies (250 to 8000 Hz).
[Analysis 1.3]
Analysis 1.3. Comparison 1 Oral steroid versus oral placebo immediately post-treatment, Outcome 3 Hearing improvement: high-tone hearing level average (4000, 8000 Hz).
[Analysis 2.1]
Analysis 2.1. Comparison 2 Oral steroid versus oral placebo at follow-up (14 to 90 days, average 33 days), Outcome 1 Hearing improvement: average speech frequencies (500, 1000, 2000 Hz).
[Analysis 2.2]
Analysis 2.2. Comparison 2 Oral steroid versus oral placebo at follow-up (14 to 90 days, average 33 days), Outcome 2 Hearing improvement: average hearing level at six frequencies (250 to 8000 Hz).
[Analysis 2.3]
Analysis 2.3. Comparison 2 Oral steroid versus oral placebo at follow-up (14 to 90 days, average 33 days), Outcome 3 Hearing improvement: high-tone hearing level average (4000, 8000 Hz).
[Analysis 3.1]
Analysis 3.1. Comparison 3 Oral steroid versus oral placebo (4 weeks and 3 months follow-up), Outcome 1 Hearing recovery (see 'Description of studies' for definition).
[Analysis 4.1]
Analysis 4.1. Comparison 4 Recovery by group for steroid-effective zone patients only (see 'Results' section), Outcome 1 Hearing recovery (see 'Description of studies' for definition).
[Analysis 5.1]
Analysis 5.1. Comparison 5 Prednisolone versus placebo, Outcome 1 Hearing improvement 8 days after treatment.
[Analysis 5.2]
Analysis 5.2. Comparison 5 Prednisolone versus placebo, Outcome 2 Hearing improvement 3 months after diagnosis of SSHL.