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Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride

  1. Niels Albert Graudal1,*,
  2. Thorbjorn Hubeck-Graudal2,
  3. Gesche Jurgens2

Editorial Group: Cochrane Hypertension Group

Published Online: 9 NOV 2011

Assessed as up-to-date: 4 OCT 2011

DOI: 10.1002/14651858.CD004022.pub3


How to Cite

Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database of Systematic Reviews 2011, Issue 11. Art. No.: CD004022. DOI: 10.1002/14651858.CD004022.pub3.

Author Information

  1. 1

    Copenhagen University Hospital, Rigshospitalet, Dep. of Rheumatology TA4242/Internal Medicine, Copenhagen, Denmark

  2. 2

    Bispebjerg University Hospital, Department of Clinical Pharmacology, Copenhagen, Denmark

*Niels Albert Graudal, Dep. of Rheumatology TA4242/Internal Medicine, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, Copenhagen, DK-2100, Denmark. graudal@dadlnet.dk.

Publication History

  1. Publication Status: New search for studies and content updated (conclusions changed)
  2. Published Online: 9 NOV 2011

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[Figure 1]
Figure 1. Forest plot of comparison: 1 Effect of salt reduction on systolic bloodpressure (SBP) and diastolic blood pressure (DBP) in whites, outcome: 1.2 Whites, normotensive, SBP.
[Figure 2]
Figure 2. Forest plot of comparison: 1 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in whites, outcome: 1.1 Whites, normotensive, DBP.
[Figure 3]
Figure 3. Forest plot of comparison: 6 Effect of salt reduction on hormones, outcome: 6.1 Renin.
[Figure 4]
Figure 4. Forest plot of comparison: 6 Effect of salt reduction on hormones, outcome: 6.2 Aldosterone.
[Figure 5]
Figure 5. Forest plot of comparison: 8 Effect of salt reduction on lipids, outcome: 8.1 Cholesterol.
[Figure 6]
Figure 6. Forest plot of comparison: 8 Effect of salt reduction on lipids, outcome: 8.2 Trigyceride.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in whites, Outcome 1 Whites, normotensive, DBP.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in whites, Outcome 2 Whites, normotensive, SBP.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in whites, Outcome 3 Whites, hypertensive, DBP.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in whites, Outcome 4 Whites, hypertensive, SBP.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Effect of salt reduction on mean blood pressure (MBP) in whites., Outcome 1 Whites, normotensive, MBP.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Effect of salt reduction on mean blood pressure (MBP) in whites., Outcome 2 Whites, hypertensive, MBP.
[Analysis 3.1]
Analysis 3.1. Comparison 3 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in whites, study duration at least 4 weeks, Outcome 1 Whites, normotensive, DBP.
[Analysis 3.2]
Analysis 3.2. Comparison 3 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in whites, study duration at least 4 weeks, Outcome 2 Whites, normotensive, SBP.
[Analysis 3.3]
Analysis 3.3. Comparison 3 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in whites, study duration at least 4 weeks, Outcome 3 Whites, hypertensive, DBP.
[Analysis 3.4]
Analysis 3.4. Comparison 3 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in whites, study duration at least 4 weeks, Outcome 4 Whites, hypertensive, SBP.
[Analysis 4.1]
Analysis 4.1. Comparison 4 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Asians, Outcome 1 Asians, normotensive, DBP.
[Analysis 4.2]
Analysis 4.2. Comparison 4 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Asians, Outcome 2 Asians, normotensive, SBP.
[Analysis 4.3]
Analysis 4.3. Comparison 4 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Asians, Outcome 3 Asians, hypertensive, DBP.
[Analysis 4.4]
Analysis 4.4. Comparison 4 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Asians, Outcome 4 Asians, hypertensive, SBP.
[Analysis 5.1]
Analysis 5.1. Comparison 5 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Blacks, Outcome 1 Blacks, normotensive, DBP.
[Analysis 5.2]
Analysis 5.2. Comparison 5 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Blacks, Outcome 2 Blacks, normotensive, SBP.
[Analysis 5.3]
Analysis 5.3. Comparison 5 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Blacks, Outcome 3 Blacks, hypertensive, DBP.
[Analysis 5.4]
Analysis 5.4. Comparison 5 Effect of salt reduction on systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Blacks, Outcome 4 Blacks, hypertensive, SBP.
[Analysis 6.1]
Analysis 6.1. Comparison 6 Effect of salt reduction on hormones, Outcome 1 Renin.
[Analysis 6.2]
Analysis 6.2. Comparison 6 Effect of salt reduction on hormones, Outcome 2 Aldosterone.
[Analysis 6.3]
Analysis 6.3. Comparison 6 Effect of salt reduction on hormones, Outcome 3 Adrenaline.
[Analysis 6.4]
Analysis 6.4. Comparison 6 Effect of salt reduction on hormones, Outcome 4 Noradrenaline.
[Analysis 7.1]
Analysis 7.1. Comparison 7 Effect of salt reduction on hormones, study duration at least two weeks, Outcome 1 Renin.
[Analysis 7.2]
Analysis 7.2. Comparison 7 Effect of salt reduction on hormones, study duration at least two weeks, Outcome 2 Aldosterone.
[Analysis 7.3]
Analysis 7.3. Comparison 7 Effect of salt reduction on hormones, study duration at least two weeks, Outcome 3 Adrenaline.
[Analysis 7.4]
Analysis 7.4. Comparison 7 Effect of salt reduction on hormones, study duration at least two weeks, Outcome 4 Noradrenaline.
[Analysis 8.1]
Analysis 8.1. Comparison 8 Effect of salt reduction on lipids, Outcome 1 Cholesterol.
[Analysis 8.2]
Analysis 8.2. Comparison 8 Effect of salt reduction on lipids, Outcome 2 Trigyceride.
[Analysis 8.3]
Analysis 8.3. Comparison 8 Effect of salt reduction on lipids, Outcome 3 High density lipoprotein, HDL.
[Analysis 8.4]
Analysis 8.4. Comparison 8 Effect of salt reduction on lipids, Outcome 4 Low density lipoprotein, LDL.
[Analysis 9.1]
Analysis 9.1. Comparison 9 Effect of salt reduction on lipids, study duration at least two weeks, Outcome 1 Cholesterol.
[Analysis 9.2]
Analysis 9.2. Comparison 9 Effect of salt reduction on lipids, study duration at least two weeks, Outcome 2 Trigyceride.
[Analysis 9.3]
Analysis 9.3. Comparison 9 Effect of salt reduction on lipids, study duration at least two weeks, Outcome 3 High density lipoprotein, HDL.
[Analysis 9.4]
Analysis 9.4. Comparison 9 Effect of salt reduction on lipids, study duration at least two weeks, Outcome 4 Low density lipoprotein, LDL.
[Analysis 10.1]
Analysis 10.1. Comparison 10 Effect of moderate salt reduction on lipids, Outcome 1 Cholesterol.
[Analysis 10.2]
Analysis 10.2. Comparison 10 Effect of moderate salt reduction on lipids, Outcome 2 Trigyceride.
[Analysis 10.3]
Analysis 10.3. Comparison 10 Effect of moderate salt reduction on lipids, Outcome 3 High density lipoprotein, HDL.
[Analysis 10.4]
Analysis 10.4. Comparison 10 Effect of moderate salt reduction on lipids, Outcome 4 Low density lipoprotein, LDL.
[Analysis 11.1]
Analysis 11.1. Comparison 11 Bias analyses, Outcome 1 Whites, normotensive, DBP perf-detec-high.
[Analysis 11.2]
Analysis 11.2. Comparison 11 Bias analyses, Outcome 2 Whites, normotensive, DBP perf-detec-low.
[Analysis 11.3]
Analysis 11.3. Comparison 11 Bias analyses, Outcome 3 Whites, normotensive, DBP outc-asses-high.
[Analysis 11.4]
Analysis 11.4. Comparison 11 Bias analyses, Outcome 4 Whites, normotensive, DBP outc-asses-low.
[Analysis 11.5]
Analysis 11.5. Comparison 11 Bias analyses, Outcome 5 Whites, normotensive, SBP perf-detec-high.
[Analysis 11.6]
Analysis 11.6. Comparison 11 Bias analyses, Outcome 6 Whites, normotensive, SBP perf-detec-low.
[Analysis 11.7]
Analysis 11.7. Comparison 11 Bias analyses, Outcome 7 Whites, normotensive, SBP outc-asses-high.
[Analysis 11.8]
Analysis 11.8. Comparison 11 Bias analyses, Outcome 8 Whites, normotensive, SBP outc-asses-low.
[Analysis 11.9]
Analysis 11.9. Comparison 11 Bias analyses, Outcome 9 Whites, hypertensive, DBP perf-detec-high.
[Analysis 11.10]
Analysis 11.10. Comparison 11 Bias analyses, Outcome 10 Whites, hypertensive, DBP perf-detec-low.
[Analysis 11.11]
Analysis 11.11. Comparison 11 Bias analyses, Outcome 11 Whites, hypertensive, DBP outc-asses-high.
[Analysis 11.12]
Analysis 11.12. Comparison 11 Bias analyses, Outcome 12 Whites, hypertensive, DBP outc-asses-low.
[Analysis 11.13]
Analysis 11.13. Comparison 11 Bias analyses, Outcome 13 Whites, hypertensive, SBP perf-detec-high.
[Analysis 11.14]
Analysis 11.14. Comparison 11 Bias analyses, Outcome 14 Whites, hypertensive, SBP perf-detec-hlow.
[Analysis 11.15]
Analysis 11.15. Comparison 11 Bias analyses, Outcome 15 Whites, hypertensive, SBP outc-asses-high.
[Analysis 11.16]
Analysis 11.16. Comparison 11 Bias analyses, Outcome 16 Whites, hypertensive, SBP outc-asses-low.