Intervention Review

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Non-antiepileptic drugs for trigeminal neuralgia

  1. Jingjing Zhang1,
  2. Mi Yang1,
  3. Muke Zhou1,
  4. Li He1,*,
  5. Ning Chen1,
  6. Joanna M Zakrzewska2

Editorial Group: Cochrane Neuromuscular Group

Published Online: 3 DEC 2013

Assessed as up-to-date: 20 MAY 2013

DOI: 10.1002/14651858.CD004029.pub4

How to Cite

Zhang J, Yang M, Zhou M, He L, Chen N, Zakrzewska JM. Non-antiepileptic drugs for trigeminal neuralgia. Cochrane Database of Systematic Reviews 2013, Issue 12. Art. No.: CD004029. DOI: 10.1002/14651858.CD004029.pub4.

Author Information

  1. 1

    West China Hospital, Sichuan University, Department of Neurology, Chengdu, Sichuan, China

  2. 2

    Eastman Dental Institute, Oral Medicine, London, UK

*Li He, Department of Neurology, West China Hospital, Sichuan University, Wai Nan Guo Xue Xiang 37#, Chengdu, Sichuan, 610041, China.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 3 DEC 2013


[Figure 1]
Figure 1. 'Risk of bias' summary: review authors' judgements about each methodological quality item for each included study. Red = high risk of bias; yellow = unclear risk of bias; green = low risk of bias
[Analysis 1.1]
Analysis 1.1. Comparison 1 Tizanidine versus carbamazepine, Outcome 1 Number improved (reported by participant on global efficacy scale).
[Analysis 2.1]
Analysis 2.1. Comparison 2 Proparacaine hydrochloride 0.5% versus placebo, Outcome 1 Number improved (reported by participant on verbal pain rating scale).
[Analysis 3.1]
Analysis 3.1. Comparison 3 Pimozide versus carbamazepine, Outcome 1 Improvement (reduction in total TN score).