Intervention Review

You have free access to this content

Non-antiepileptic drugs for trigeminal neuralgia

  1. Jingjing Zhang1,
  2. Mi Yang1,
  3. Muke Zhou1,
  4. Li He1,*,
  5. Ning Chen1,
  6. Joanna M Zakrzewska2

Editorial Group: Cochrane Neuromuscular Group

Published Online: 3 DEC 2013

DOI: 10.1002/14651858.CD004029.pub4


How to Cite

Zhang J, Yang M, Zhou M, He L, Chen N, Zakrzewska JM. Non-antiepileptic drugs for trigeminal neuralgia. Cochrane Database of Systematic Reviews 2013, Issue 12. Art. No.: CD004029. DOI: 10.1002/14651858.CD004029.pub4.

Author Information

  1. 1

    West China Hospital, Sichuan University, Department of Neurology, Chengdu, Sichuan, China

  2. 2

    Eastman Dental Institute, Oral Medicine, London, UK

*Li He, Department of Neurology, West China Hospital, Sichuan University, Wai Nan Guo Xue Xiang 37#, Chengdu, Sichuan, 610041, China. heli2003new@126.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 3 DEC 2013

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Kondziolka 1994 {published data only}
  • Kondziolka D, Lemley T, Kestle JR, Lunsford LD, Fromm GH, Jannetta PJ. The effect of single-application topical ophthalmic anesthesia in patients with trigeminal neuralgia. A randomized double-blind placebo-controlled trial. Journal of Neurosurgery 1994;80(6):993-7. [PUBMED: 8189280]
Lechin 1989 {published data only}
Lindström 1987 {published data only}
Vilming 1986 {published data only}

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Carasso 1979 {published data only}
Fromm 1984 {published data only}
Fromm 1987 {published data only}
Fromm 1993 {published data only}
Gazerani 2009 {published data only}
  • Gazerani P, Pedersen NS, Staahl C, Drewes AM, Arendt-Nielsen L. Subcutaneous botulinum toxin type A reduces capsaicin-induced trigeminal pain and vasomotor reactions in human skin. Pain 2009;141(1-2):60-9. [PUBMED: 19004549]
Gilron 2000 {published data only}
Jiang 2007 {published data only}
  • Jiang L, Niu G. Therapeutic effect observation of neurotropin in the treatment of senile essential trigeminal neuralgia. Chinese Journal of Practical Nervous Diseases 2007;10(7):25-6.
Jiang 2008 {published data only}
  • Jiang L, Niu G. The effect of neurotropin on idiopathic trigeminal neuralgia. Zhejiang Medical Journal 2008;30(6):644-5.
Kanai 2006a {published data only}
Kanai 2006b {published data only}
Kanai 2006c {published data only}
Laurinda 2008 {published data only}
  • Lemos L, Flores S, Oliveira P, Almeida A. Gabapentin supplemented with ropivacain block of trigger points improves pain control and quality of life in trigeminal neuralgia patients when compared with gabapentin alone. Clinical Journal of Pain 2008;24(1):64-75. [PUBMED: 18180639]
Liu 1999 {published data only}
  • Liu Y, Deng X. Effect analysis of low dosage meticorten in trigeminal neuralgia. Journal of North Sichuan Medical College 1999;14(2):84-5.
Luo 1995 {published data only}
  • Luo X, Chen M, Guo K, Zhang M, Li Z. Control study of the effect of tiapride together with doxa in trigeminal neuralgia. Journal of Brain and Nervous Disease 1995;3(1):58.
Parekh 1989 {published data only}
  • Parekh S, Shah K, Kotdawalla H, Gandhi I. Baclofen in carbamazepine resistant trigeminal neuralgia - A double blind clinical trial. Cephalalgia 1989;9 Suppl 10:392-3. [EMBASE: 1990167097]
Shao 1999 {published data only}
  • Shao J, Xiang F, Ying J, Wang H. The clinical observation of tramadol and doxa in trigeminal neuralgia. Journal of Yunyang Medical College 1999;18(2):106-7.
Shao 2011 {published data only}
  • Shao YQ. Methycobal in trigeminal neuralgia [弥可保治疗三叉神经痛50例疗效观察]. Asia-Pacific Traditional Medicine 2011;7:63-4.
Silver 2007 {published data only}
  • Silver M, Blum D, Grainger J, Hammer AE, Quessy S. Double-blind, placebo-controlled trial of lamotrigine in combination with other medications for neuropathic pain. Journal of Pain and Symptom Management 2007;34(4):446-54. [PUBMED: 17662571]
Stajcic 1990 {published data only}
  • Stajcic Z, Juniper RP, Todorovic L. Peripheral streptomycin/lidocaine injections versus lidocaine alone in the treatment of idiopathic trigeminal neuralgia. A double blind controlled trial. Journal of Cranio-Maxillo-Facial Surgery 1990;18(6):243-6. [PUBMED: 2212020]
Wang 2007 {published data only}
  • Wang X, Li W. Shenjingzhitongsan for trigeminal neuralgia [Shenjingzhitongsan zhi liao san cha shen jing tong 128 li]. Henan Traditional Chinese Medicine 2007;27(4):35.
Xu 1998 {published data only}
  • Xu Z. The analgesic effect of mexiletine in idiopathic trigeminal neuralgia. Central Plains Medical Journal 1998;25(3):33.
Yan 2011 {published data only}
  • Yan HM. Clinical observation of botulinum toxin type A in trigeminal neuralgia [A型肉毒毒素治疗三叉神经痛64例临床观察]. Jilin Medical Journal 2011;32:6821-2.
Zhao 2011 {published data only}
  • Zhao Y. The efficacy of carbamazepine combined with doxepin treatment of primary trigeminal neuralgia [卡马西平联用多虑平治疗原发性三叉神经痛疗效观察]. Guide of China Medicine 2011;9:36-7.

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
NCT00004431 {published data only}
  • NCT00004431. Randomized study of L-baclofen in patients with refractory trigeminal neuralgia. clinicaltrials.gov/show/NCT00004431 (accessed 5 November 2013).
NCT01540630 {published data only}
  • NCT01540630. A phase IIa withdrawal study of CNV1014802 in patients with trigeminal neuralgia. http://clinicaltrials.gov/show/NCT01540630 (accessed 5 November 2013).

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Anonymous 2004
  • International Headache Society Classification Subcommittee. International Classification of Headache Disorders. Cephalalgia 2004;24 Suppl 1:1-160.
Beydoun 2002
  • Beydoun A, Schmidt D, D'Souza J. Oxcarbazepine versus carbamazepine in trigeminal neuralgia: a meta-analysis of three double blind comparative trials. Neurology 2002;58 Suppl 3:831-2.
Cheng 1993
Cruccu 2008
Devor 2002
Dworkin 2005
  • Dworkin RH, Turk DC, Farrar JT, Haythornthwaite JA, Jensen MP, Katz NP, et al. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain 2005;113(1-2):9-19. [PUBMED: 15621359]
Fusco 1992
GRADE working group 2004
Gronseth 2008
  • Gronseth G, Cruccu G, Alksne J, Argoff C, Brainin M, Burchiel K, et al. Practice parameter: the diagnostic evaluation and treatment of trigeminal neuralgia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the European Federation of Neurological Societies. Neurology 2008;71(15):1183-90. [PUBMED: 18716236]
Higgins 2008
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 [updated September 2008]. The Cochrane Collaboration, 2008. Available from www.cochrane-handbook.org.
Higgins 2011
  • Higgins JPT, Altman DG, Sterne JAC (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S(editors). Cochrane Handbook for Systematic Reviews of Intervention Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Jacox 1994
  • Jacox A, Carr DB, Payne R. Management of cancer pain. US Department of Health and Human Services, Public Health Service. Clinical Practice Guideline 1994.
Katusic 1990
Koopman 2009
Lemos 2008
  • Lemos L, Flores S, Oliveira P, Almeida A. Gabapentin supplemented with ropivacain block of trigger points improves pain control and quality of life in trigeminal neuralgia patients when compared with gabapentin alone. Clinical Journal of Pain 2008;24(1):64-75. [PUBMED: 18180639 ]
Mathisen 1995
Merskey 1994
  • Merskey H, Bogduk N. Classification of Chronic Pain: Descriptions of Chronic Pain Syndromes and Definitions of Pain Terms. 2nd Edition. Seattle: IASP Press, 1994:59-71. [0931092051]
Moore 2009
Nurmikko 2001
Obermann 2007
  • Obermann M, Yoon MS, Ese D, Maschke M, Kaube H, Diener HC, et al. Impaired trigeminal nociceptive processing in patients with trigeminal neuralgia. Neurology 2007;69(9):835-41. [PUBMED: 17724285 ]
Obermann 2008
  • Obermann M, Yoon MS, Sensen K, Maschke M, Diener HC, Katsarava Z. Efficacy of pregabalin in the treatment of trigeminal neuralgia. Cephalalgia 2008;28(2):174-81. [PUBMED: 18039340]
Rawson 1998
  • Rawson NS, Harding SR, Malcolm E, Lueck L. Hospitalizations for aplastic anemia and agranulocytosis in Saskatchewan: incidence and associations with antecedent prescription drug use. Journal of Clinical Epidemiology 1998;51(12):1343-55. [PUBMED: 10086829]
Reder 1995
RevMan 2012 [Computer program]
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2012.
Schünemann 2011a
  • Schünemann HJ, Oxman AD, Higgins JPT, Vist GE, Glasziou P, Guyatt GH. Chapter 11: Presenting results and 'Summary of findings' tables. In: Higgins JPT, Green S (editors), Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Schünemann 2011b
  • Schünemann HJ, Oxman AD, Vist GE, Higgins JPT, Deeks JJ, Glasziou P, et al. Chapter 12: Interpreting results and drawing conclusions. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Sindrup 1999
Sindrup 2002
Steardo 1984
Taylor 1981
Ware 1992
Wiffen 2010a
Wiffen 2010b
  • Wiffen PJ, McQuay HJ, Rees J, Moore RA. Gabapentin for acute and chronic pain. Cochrane Database of Systematic Reviews 2005, Issue 3. [DOI: 10.1002/14651858.CD005452]
Wiffen 2011
Yoshimasu 1972
Zakrzewska 1997
  • Zakrzewska JM, Chaudhry Z, Nurmikko TJ, Patton DW, Mullens EL. Lamotrigine (Lamictal) in refractory trigeminal neuralgia: results from a double-blind placebo controlled crossover trial. Pain 1997;73(2):223-30. [PUBMED: 9415509]
Zakrzewska 2002a
Zakrzewska 2002b
Zakrzewska 2009
  • Zakrzewska JM, Linskey M. Trigeminal neuralgia. Clinical Evidence. http://clinicalevidence.bmj.com/ceweb/conditions/nud/1207/1207.jsp 2009 (accessed April 2010).

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
He 2006
Yang 2011