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Intervention Protocol

Alpha-2 adrenergic agonists for the prevention of cardiovascular complications among patients undergoing cardiac or non-cardiac surgery

  1. Duminda N Wijeysundera1,*,
  2. Jennifer S Bender2,
  3. W Scott Beattie3

Editorial Group: Cochrane Anaesthesia Group

Published Online: 8 JUL 2009

DOI: 10.1002/14651858.CD004126

Database Title

Additional Information

How to Cite

Wijeysundera DN, Bender JS, Beattie WS. Alpha-2 adrenergic agonists for the prevention of cardiovascular complications among patients undergoing cardiac or non-cardiac surgery (Protocol). Cochrane Database of Systematic Reviews 2003, Issue 2. Art. No.: CD004126. DOI: 10.1002/14651858.CD004126.

Author Information

  1. 1

    University of Toronto, Department of Anaesthesia, Toronto, Ontario, Canada

  2. 2

    St Jospeh's Health Centre, Department of Anaesthesia, Toronto, Ontario, Canada

  3. 3

    Toronto General Hospital, University Health Network, Department of Anaesthesia, Toronto, Ontario, Canada

*Duminda N Wijeysundera, Department of Anaesthesia, University of Toronto, Department of Anaesthesia, EN 3-437, Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario, M5G 2C4, Canada. duminda.wijeysundera@uhn.on.ca. w_duminda@hotmail.com.

Publication History

  1. Publication Status: Unchanged
  2. Published Online: 8 JUL 2009

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Abstract

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  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary objective:
To determine the efficacy and safety of alpha-2 adrenergic agonists for reducing mortality and cardiovascular complications following cardiac and non-cardiac surgery.

Secondary objectives:

  1. To compare the efficacy and safety of clonidine, mivazerol, and dexmedetomidine for reducing mortality and cardiovascular complications following cardiac and non-cardiac surgery.
  2. To compare the efficacy and safety of alpha-2 adrenergic agonists for reducing mortality and cardiovascular complications following cardiac, vascular non-cardiac, and non-vascular non-cardiac surgery.

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