Intervention Review

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Screening programmes for the early detection and prevention of oral cancer

  1. Paul Brocklehurst1,*,
  2. Omar Kujan2,3,
  3. Lucy A O'Malley4,
  4. Graham Ogden5,
  5. Simon Shepherd6,
  6. Anne-Marie Glenny7

Editorial Group: Cochrane Oral Health Group

Published Online: 19 NOV 2013

Assessed as up-to-date: 22 JUL 2013

DOI: 10.1002/14651858.CD004150.pub4


How to Cite

Brocklehurst P, Kujan O, O'Malley LA, Ogden G, Shepherd S, Glenny AM. Screening programmes for the early detection and prevention of oral cancer. Cochrane Database of Systematic Reviews 2013, Issue 11. Art. No.: CD004150. DOI: 10.1002/14651858.CD004150.pub4.

Author Information

  1. 1

    School of Dentistry, The University of Manchester, Manchester, UK

  2. 2

    School of Dentistry, AlBaath University, Oral Pathology and Medicine, Hama, Syrian Arab Republic

  3. 3

    Al-Farabi College, Department of Oral and Maxillofacial Sciences, School of Dentistry, Riyadh, Saudi Arabia

  4. 4

    The University of Manchester, School of Dentistry, Manchester, Greater Manchester, UK

  5. 5

    University of Dundee, Division of Oral and Maxillofacial Clinical Sciences, School of Dentistry, Dundee, Scotland, UK

  6. 6

    University of Dundee, Department of Oral Surgery & Medicine, School of Dentistry, Dundee, Scotland, UK

  7. 7

    School of Dentistry, The University of Manchester, Cochrane Oral Health Group, Manchester, UK

*Paul Brocklehurst, School of Dentistry, The University of Manchester, Coupland III Building, Oxford Road, Manchester, M13 9PL, UK. paul.brocklehurst@manchester.ac.uk. paul.r.brocklehurst@btopenworld.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 19 NOV 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Sankaranarayanan 2000 {published data only}
  • Ramadas K, Sankaranarayanan R, Jacob BJ, Thomas G, Somanathan T, Mahe C, et al. Interim results from a cluster randomized controlled oral cancer screening trial in Kerala, India. Oral Oncolgy 2003;39(6):580-8.
  • Sankaranarayanan R, Mathew B, Jacob BJ, Thomas G, Somanathan T, Pisani P, et al. Early findings from a community-based, cluster-randomized, controlled oral cancer screening trial in Kerala, India. Cancer 2000;88(3):664-73.
  • Sankaranarayanan R, Ramadas K, Thara S, Muwonge R, Thomas G, Anju G, et al. Long term effect of visual screening on oral cancer incidence and mortality in a randomized trial in Kerala, India. Oral Oncology 2013;49(4):314-21.
  • Sankaranarayanan R, Ramadas K, Thomas G, Muwonge R, Thara S, Mathew B, et al. Effect of screening on oral cancer mortality in Kerala, India: a cluster-randomised controlled trial. Lancet 2005;365(9475):1927-33.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Allen 1998 {published data only}
Chamberlain 1993 {published data only}
  • Chamberlain J. Evaluation of screening for cancer. Community Dental Health 1993;10 Suppl(1):5-11.
Chen 2004 {published data only}
Cheng 2003 {published data only}
  • Cheng B, Yang L. The clinical evaluation of Oratest in detecting oral mucosal lesions. Hua Xi Kou Qiang Yi Xue Za Zhi 2003;21(2):124-6.
Eliezri 1988 {published data only}
  • Eliezri YD. The toluidine blue test: an aid in the diagnosis and treatment of early squamous cell carcinomas of mucous membranes. Journal of American Academy of Dermatology 1988;18(6):1339-49.
Garrote 1995 {published data only}
  • Frenández Garrote L, Sankaranarayanan R, Lence Anta JJ, Rodriguez Salvá A, Maxwell Parkin D. An evaluation of the oral cancer control program in Cuba. Epidemiology 1995;6(4):428-31.
Gray 2000 {published data only}
  • Gray M, Gold L, Elley A, Bursla A. The Effectiveness of Toluidine Blue Dye as Adjunct to Oral Cancer Screening in General Dental Practice. Birmingham: University of Birmingham, Department of Public Health & Epidemiology, 2000.
Gupta 1986 {published data only}
  • Gupta PC, Mehta FS, Pindborg JJ, Aghi MB, Bhonsle RB, Daftery DK, et al. Intervention study for primary prevention of oral cancer among 36 000 Indian tobacco users. Lancet 1986;1(8492):1235-9.
Gupta 1992 {published data only}
Ikeda 1991 {published data only}
  • Ikeda N, Ishii T, Iida S, Kawai T. Epidemiological study of oral leukoplakia based on mass screening for oral mucosal diseases in a selected Japanese population. Community Dentistry and Oral Epidemiology 1991;19(3):160-3.
Ikeda 1995 {published data only}
  • Ikeda N, Downer MC, Ishii T, Fukano H, Nagao T, Inoue K. Annual screening for oral cancer and precancer by invitation to 60-year-old residents of a city in Japan. Community Dental Health 1995;12(3):133-7.
Lavelle 2005 {published data only}
Martin 1998 {published data only}
  • Martin IC, Kerawala CJ, Reed M. The application of toluidine blue as a diagnostic adjunct in the detection of epithelial dysplasia. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 1998;85(4):444-6.
Miller 1988 {published data only}
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Mullhaupt 2004 {published data only}
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Nagao 2000 {published data only}
  • Nagao T, Warnakulasuriya S, Ikeda N, Fukano H, Fujiwara K, Miyazaki H. Oral cancer screening as an integral part of general health screening in Tokoname City, Japan. Journal of Medical Screening 2000;7(4):203-8.
Nagao 2000a {published data only}
Nagao 2003 {published data only}
Patton 2003 {published data only}
Sankaranarayanan 1997 {published data only}
Sankaranarayanan 2002 {published data only}
Silverman 1984 {published data only}
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Su 2010 {published data only}
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Zhang 2005 {published data only}
  • Zhang L, Williams M, Poh CF, Laronde D, Epstein JB, Durham S, et al. Toluidine blue staining identifies high-risk primary oral premalignant lesions with poor outcome. Cancer Research 2005;65(17):8017-21.

Additional references

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  3. Additional references
  4. References to other published versions of this review
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References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Brocklehurst 2010c
Kujan 2003
  • Kujan O, Glenny AM, Duxbury AJ, Thakker N, Sloan P. Screening programmes for the early detection and prevention of oral cancer. Cochrane Database of Systematic Reviews 2003, Issue 4. [DOI: 10.1002/14651858.CD004150]
Kujan 2006