Intervention Review

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Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications

  1. Marco Esposito1,*,
  2. Maria Gabriella Grusovin2,
  3. Helen V Worthington1

Editorial Group: Cochrane Oral Health Group

Published Online: 31 JUL 2013

DOI: 10.1002/14651858.CD004152.pub4


How to Cite

Esposito M, Grusovin MG, Worthington HV. Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications. Cochrane Database of Systematic Reviews 2013, Issue 7. Art. No.: CD004152. DOI: 10.1002/14651858.CD004152.pub4.

Author Information

  1. 1

    School of Dentistry, The University of Manchester, Cochrane Oral Health Group, Manchester, UK

  2. 2

    Private practice, Gorizia, Italy

*Marco Esposito, Cochrane Oral Health Group, School of Dentistry, The University of Manchester, Coupland 3 Building, Oxford Road, Manchester, M13 9PL, UK. espositomarco@hotmail.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 31 JUL 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Abu-Ta'a 2008 {published data only}
  • Abu-Ta'a M, Quirynen M, Teughels W, van Steenberghe D. Asepsis during periodontal surgery involving oral implants and the usefulness of peri-operative antibiotics: a prospective, randomized, controlled clinical trial. Journal of Clinical Periodontology 2008;35(1):58-63.
Anitua 2009 {published data only}
  • Anitua E, Aguirre JJ, Gorosabel A, Barrio P, Errazquin JM, Román P, et al. A multicentre placebo-controlled randomised clinical trial of antibiotic prophylaxis for placement of single dental implants. European Journal of Oral Implantology 2009;2(4):283-92.
Caiazzo 2011 {published and unpublished data}
  • Caiazzo A, Casavecchia P, Barone A, Brugnami F. A pilot study to determine the effectiveness of different amoxicillin regimens in implant surgery. Journal of Oral Implantology 2011;37:691-6.
Esposito 2008a {published data only}
  • Esposito M, Cannizzaro G, Bozzoli P, Consolo U, Felice P, Ferri V, et al. Efficacy of prophylactic antibiotics for dental implants: a multicentre placebo-controlled randomised clinical trial. European Journal of Oral Implantology 2008;1(1):23-31.
Esposito 2010a {published data only}
  • Esposito M, Cannizzaro G, Bozzoli P, Checchi L, Ferri V, Landriani S, et al. Effectiveness of prophylactic antibiotics at placement of dental implants: a pragmatic multicenter placebo-controlled randomized clinical trial. European Journal of Oral Implantology in press.
Nolan 2013 {published and unpublished data}
  • Nolan R, Kemmoona M, Polyzois I, Claffey N. The influence of prophylactic antibiotic administration on post-operative morbidity in dental implant surgery. A prospective double blind randomized controlled clinical trial. Clinical Oral Implants Research 2013 Feb 13 [Epub ahead of print].

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Tan 2013 {published data only}
  • Tan WC, Ong M, Han J, Mattheos N, Pjetursson BE, Tsai AY, et al. Effect of systemic antibiotics on clinical and patient-reported outcomes of implant therapy - a multicenter randomized controlled clinical trial. Clinical Oral Implants Research 2013 Jan 24 [Epub ahead of print].

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Adell 1985
  • Adell R, Lekholm U, Branemark PI. Surgical procedures. In: Branemark PI, Zarb GA, Albrektsson T editor(s). Tissue-integrated prostheses. Chicago: Quintessence Publishing Co, Inc, 1985:211-32.
Binahmed 2005
  • Binahmed A, Stoykewych A, Peterson L. Single preoperative dose versus long-term prophylactic antibiotic regimens in dental implant surgery. The International Journal of Oral and Maxillofacial Implants 2005;20(1):115-7.
Dent 1997
  • Dent CD, Olson JW, Farish SE, Bellome J, Casino AJ, Morris HF, et al. The influence of preoperative antibiotics on success of endosseous implants up to and including stage II surgery: a study of 2,641 implants. Journal of Oral and Maxillofacial Surgery 1997;55(12 Suppl 5):19-24.
Egger 1997
Esposito 1998a
Esposito 1998b
Esposito 1999
  • Esposito M, Thomsen P, Ericson LE, Lekholm U. Histopathologic observations on early oral implant failures. The International Journal of Oral and Maxillofacial Implants 1999;14(6):798-810.
Flemmig 1990
  • Flemmig TF, Newman MG. Antimicrobials in implant dentistry. In: Newman MG, Kornman K editor(s). Antibiotics/antimicrobial use in dental practice. Chicago: Quintessence Publishing Co, Inc, 1990:187-200.
Gynther 1998
  • Gynther GW, Kondell PA, Moberg LE, Heimdahl A. Dental implant installation without antibiotic prophylaxis. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics 1998;85(5):509-11.
Higgins 2011
  • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Laskin 2000
  • Laskin DM, Dent CD, Morris HF, Ochi S, Olson JW. The influence of preoperative antibiotics on success of endosseous implants at 36 months. Annals of Periodontology 2000;5(1):166-74.
Lindeboom 2003
  • Lindeboom JA, van den Akker HP. A prospective placebo-controlled double-blind trial of antibiotic prophylaxis in intraoral bone grafting procedures: a pilot study. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics 2003;96(6):669-72.
Lindeboom 2005
  • Lindeboom JA, Tuk JG, Kroon FH, van den Akker HP. A randomized prospective controlled trial of antibiotic prophylaxis in intraoral bone grafting procedures: single-dose clindamycin versus 24-hour clindamycin prophylaxis. Mund-, Kiefer- und Gesichtschirurgie 2005;9(6):384-8.
Lindeboom 2006
  • Lindeboom JA, Frenken JW, Tuk JG, Kroon FH. A randomized prospective controlled trial of antibiotic prophylaxis in intraoral bone-grafting procedures: preoperative single-dose penicillin versus preoperative single-dose clindamycin. International Journal of Oral and Maxillofacial Surgery 2006;35(5):433-6.
RevMan 2013 [Computer program]
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2013.
Schwartz 2007
  • Schwartz AB, Larson EL. Antibiotic prophylaxis and postoperative complications after tooth extraction and implant placement: a review of the literature. Journal of Dentistry 2007;35(12):881-8.

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. Additional references
  4. References to other published versions of this review
Esposito 2003
  • Esposito M, Coulthard P, Oliver R, Thomsen P, Worthington HV. Antibiotics to prevent complications following dental implant treatment. Cochrane Database of Systematic Reviews 2003, Issue 3. [DOI: 10.1002/14651858.CD004152]
Esposito 2008b
  • Esposito M, Grusovin MG, Talati M, Coulthard P, Oliver R, Worthington HV. Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications. Cochrane Database of Systematic Reviews 2008, Issue 3. [DOI: 10.1002/14651858.CD004152.pub2]
Esposito 2008c
  • Esposito M, Grusovin MG, Coulthard P, Oliver R, Worthington HV. The efficacy of antibiotic prophylaxis at placement of dental implants: a Cochrane systematic review of randomized controlled clinical trials. European Journal of Oral Implantology 2008;1(2):95-103.
Esposito 2010b
  • Esposito M, Grusovin MG, Loli V, Coulthard P, Worthington HV. Effectiveness of prophylactic antibiotics at placement of dental implants: a Cochrane systematic review. European Journal of Oral Implantology 2010;3:101-10.
Esposito 2010c
Esposito 2011
  • Esposito M, Worthington HW, Loli V, Coulthard P, Grusovin MG. Effectiveness of prophylactic antibiotics at placement of dental implants: a Cochrane systematic review [La profilassi antibiotica all’inserimento implantare può ridurre i fallimenti precoci? Una revisione sistematica Cochrane]. Rivista Italiana di Stomatologia 2011;79(1):18-28.