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Tissue adhesives for closure of surgical incisions

  1. Paul Coulthard1,*,
  2. Marco Esposito2,
  3. Helen V Worthington3,
  4. Maarten van der Elst4,
  5. Oscar J F van Waes4,
  6. James Darcey2

Editorial Group: Cochrane Wounds Group

Published Online: 12 MAY 2010

Assessed as up-to-date: 16 NOV 2009

DOI: 10.1002/14651858.CD004287.pub3


How to Cite

Coulthard P, Esposito M, Worthington HV, van der Elst M, van Waes OJF, Darcey J. Tissue adhesives for closure of surgical incisions. Cochrane Database of Systematic Reviews 2010, Issue 5. Art. No.: CD004287. DOI: 10.1002/14651858.CD004287.pub3.

Author Information

  1. 1

    School of Dentistry, The University of Manchester, Oral and Maxillofacial Surgery, Manchester, UK

  2. 2

    School of Dentistry, The University of Manchester, Department of Oral and Maxillofacial Surgery, Manchester, UK

  3. 3

    School of Dentistry, The University of Manchester, Cochrane Oral Health Group, Manchester, UK

  4. 4

    Reinier de Graaf Groep, Department of Surgery, Delft, Netherlands

*Paul Coulthard, Oral and Maxillofacial Surgery, School of Dentistry, The University of Manchester, Coupland III Building, Oxford Road, Manchester, M13 9PL, UK. paul.coulthard@manchester.ac.uk.

Publication History

  1. Publication Status: Edited (no change to conclusions)
  2. Published Online: 12 MAY 2010

SEARCH

References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
Blondeel 2004 {published data only}
  • Blondeel P, Murphy J, Debrosse D, Nix, J, Puls LE, Theodore N, Coulthard P. Closure of long surgical incisions with a new formulation of 2-octylcyanoacrylate tissue adhesive versus commercially available methods. American Journal of Surgery 2004;188:307-13.
Cheng 1997 {published data only}
Dowson 2006 {published data only}
  • Dowson C, Gilliam A, Speake W, Lobo D, Beckingham. A prospective, randomised controlled trial comparing n-butyl cyanoacrylate tissue adhesive (Liquiband) with sutures for skin closure after laparoscopic general surgical procedures. Surgical Laparoscopy, Endoscopy and Percutaneous Techniques 2006;16(3):146-50.
Greene 1999 {published data only}
  • Greene D, Kock RJ, Goode RL. Efficacy of octyl-2-cyanoacrylate tissue glue in blepharoplasty. Archives of Facial Plastic Surgery 1999;1:292-6.
Keng 1989 {published data only}
  • Keng TM, Bucknall TE. A clinical trial of tissue adhesive (histoacryl) in skin closure of groin wounds. Medical Journal of Malaysia 1989;44(2):122-8.
Maartense 2002 {published data only}
  • Maartense S, Bemelman WA, Dunker MS, de Lint C, Pierik EGJM, Busch ORC, Gouma DJ. Randomised study of the effectiveness of closing laparoscopic trocar wounds with octylcyanoacrylate, adhesive papertape or poliglecaprone. British Journal of Surgery 2002;89:1370-5.
Ong 2002 {published data only}
  • Ong C, Jacobsen A, Joseph V. Comparing wound closure using tissue glue versus subcuticular suture for paediatric surgical incisions: a prospective, randomised trial. Paediatric Surgery International 2002;18:553-5.
Ozturan 2001 {published data only}
  • Ozturan O, Miman MC, Aktas D, Oncel S. Butylcyanoacrylate tissue adhesive for columellar incision closure. The Journal of Laryngology and Otology 2001;115:535-40.
Ridgway 2007 {published data only}
  • Ridgway D, Mahmood F, Moore L, Bramley D, Moore P. A blinded, randomised, controlled trial of stapled versus tissue glue closure of neck surgery incisions. Annals of the Royal College of Surgeons of England 2007;89(3):242-6.
Shamiyeh 2001 {published data only}
Sinha 2001 {published data only}
  • Sinha S, Naik M, Wright V, Timmons J, Campbell AC. A single blind, prospective, randomised trial comparing n-butyl 2-cyanoacrylate tissue adhesive (Indermil) and sutures for skin closure in hand surgery. Journal of Hand Surgery 2001;26B(3):264-5.
Sniezek 2007 {published data only}
Switzer 2003 {published data only}
Toriumi 1998 {published data only}

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
Alhopuro 1976 {published data only}
  • Alhopuro S, Rintala A, Salo H, Ritsila V. Tissue adhesive versus sutures in closure of incision wounds. A comparative study in human skin. Annales Chirurgiae et Gynaecologiae 1976;65:308-12.
Gorozpe-Calvillo 99 {published data only}
  • Gorozpe-Calvillo JI, Gonzalez-Villamil J, Santoya-Haro S. Closure of the skin with cyanoacrylate in caesarian surgery [Cierre de la piel con cianoacrilato en las cesareas]. Ginecologia y Obstetricia de Mexico 1999;67:491-5.
Jaibaji 2000 {published data only}
  • Jaibaji M, Liddington M, Geary P, Darcy C, Batchelor A, Roberts A. Evaluation of the long term outcome of wounds closed with "Indermil" adhesive. European Journal of Plastic Surgery 2000;23:330-2.
Kuo 2006 {published data only}
Orozco-Razon 2002 {published data only}
  • Ozturan O, Mimam N, Aktas D, Oncel S. Butylcyanoacrylate tissue adhesive for columellar incision closure. The Journal of Laryngology and Otology 2001;115:535-40.
Silvestri 2006 {published data only}
  • Silvestri A, Brandi C, Grimaldi L, Nisi G, Brafa A, Calabro M, et al. Octyl-2-cyanoacrylate adhesive for skin closure and prevention of infection in plastic surgery. Aesthetic Plastic Surgery 2006;30:695-9.
Singer 2002 {published data only}
Steiner 2000 {published data only}
  • Steiner Z, Mogilner J. Histoacryl vs Dermabond cyanoacrylate glue for closing small operative wounds. Harefuah 2000;139(11-12):409-11, 496.

References to studies awaiting assessment

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
Amin 2009 {published data only}
  • Amin M, Glynn F, Timon C. Randomised trial of tissue adhesive vs staples in thyroidectomy integrating patient satisfaction and Manchester score. Otolaryngology - Head and Neck Surgery 2009;140(5):703-8.
Brown 2009 {published data only}
  • Brown JK, Campbell BT, Drongowski RA, Alderman AK, Geiger JD, Teitelbaum DH, Quinn J, Coran AG, Hirschl RB. A prospective, randomized comparison of skin adhesive and subcuticular suture for closure of pediatric hernia incisions: cost and cosmetic considerations. Journal of Paediatric Surgery 2009;44(7):1418-22.
Chibbaro 2009 {published data only}
  • Chibbaro S, Tacconi L. Use of skin glue versus traditional wound closure methods in brain surgery: A prospective, randomized, controlled study. Journal of Clinical Neuroscience 2009;16(4):535-9.
Mota 2009 {published data only}
Sajid 2009 {published data only}
Sun 2005 {published data only}
  • Sun J, Chen Q-M, Zhang M, Shi C. Octylcyanoacrylate versus absorbable suture in the repair of skin wounds in children. Zhongguo Linchuang Kangfu 2005;9(19):186-7.
Tierny 2009 {published data only}
  • Tierney EP, Moy RL, Kouba DJ. Rapid absorbing gut suture versus 2-octylethylcyanoacrylate tissue adhesive in the epidermal closure of linear repairs. Journal of Drugs in Dermatology 2009;8(2):115-9.

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to studies awaiting assessment
  4. Additional references
Bruns 1996
Coover 1959
  • Coover HN, Joyner FB, Sheere NH. Chemistry and performance of cyanoacrylate adhesive. Journal of the Society of Plastic Surgery of England 1959;1:5-6.
Dunker 1998
  • Dunker MS, Stiggelbout AM, van Hogezand RA, Ringers J, Griffioen G, Bemelman WA. Cosmesis and body image after laparoscopic assisted and ileocolic resection for Crohn's disease. Surgical Endoscopy 1998;12:1334-40.
Emori 1993
Farion 2001
  • KJ Farion, KF Russell, MH Osmond, L Hartling, TP Klassen, T Durec, B Vandermeer. Tissue adhesives for traumatic lacerations in children and adults. Cochrane Database of Systematic Reviews 2001, Issue 4. [DOI: 10.1002/14651858.CD003326]
Hollander 1995
Houston 1969
  • Houston S, Hodge JW Jr, Ousterhout DK, Leonard F. The effect of alpha-cyanoacrylates on wound healing. Journal of Biomedical Materials Research 1969;3(2):281-9.
Lefebvre 2008
  • Lefebvre C, Manheimer E, Glanville J. Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 (updated September 2008). The Cochrane Collaboration, 2008. Available from www.cochrane-handbook.org.
Malone 2002
Osmond 1999
Perron 2000
  • Perron AD, Garcia JA, Hays EP. The efficacy of cyanoacrylate-derived surgical adhesive for use in the repair of lacerations during competitive athletics. American Journal of Emergency Medicine 2000;18:261-3.
Quinn 1993
  • Quinn JV, Drzewiecki A, Li MM, Stiell IG, Sutcliffe T, Elmslie TJ, Wood WE. A randomised, controlled trial comparing a tissue adhesive with suturing in the repair of paediatric facial lacerations. Annals of Emergency Medicine 1993;22:1130-5.
Quinn 1995
Quinn 1997
Quinn 1998
  • Quinn J, Wells G, Sutcliffe T, Jarmuske M, Maw J, Stiell I, Johns P. Tissue adhesive versus suture wound repair at 1 year: randomized clinical trial correlating early, 3-month, and 1-year cosmetic outcome. Annals of Emergency Medicine 1998;32(6):645-9.
SIGN 2009
  • Scottish Intercollegiate Guidelines Network (SIGN). Search filters. http://www.sign.ac.uk/methodology/filters.html#random (accessed 17 November 2009).