Intervention Review

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Prevention and treatment of postpartum hypertension

  1. Laura Magee1,*,
  2. Peter von Dadelszen2

Editorial Group: Cochrane Pregnancy and Childbirth Group

Published Online: 30 APR 2013

Assessed as up-to-date: 12 FEB 2013

DOI: 10.1002/14651858.CD004351.pub3


How to Cite

Magee L, von Dadelszen P. Prevention and treatment of postpartum hypertension. Cochrane Database of Systematic Reviews 2013, Issue 4. Art. No.: CD004351. DOI: 10.1002/14651858.CD004351.pub3.

Author Information

  1. 1

    British Columbia Women's Hospital and Health Centre, Departments of Internal Medicine (UBC) and Specialized Women's Health (BC Women's Hospital), Vancouver, British Columbia, Canada

  2. 2

    University of British Columbia, Department of Obstetrics and Gynaecology, Vancouver, BC, Canada

*Laura Magee, Departments of Internal Medicine (UBC) and Specialized Women's Health (BC Women's Hospital), British Columbia Women's Hospital and Health Centre, 4500 Oak Street, Suite 1U59, Vancouver, British Columbia, V6H 3N1, Canada. lmagee@cw.bc.ca.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 30 APR 2013

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References

References to studies included in this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Ascarelli 2005 {published data only}
  • Ascarelli M, Johnson V, McCreary H, May WL, Martin JN Jr. Adjunctive postpartum treatment of preeclampsia with furosemide. Obstetrics & Gynecology 1999;180(1 Pt 2):S18.
  • Ascarelli MH, Johnson V, McCreary H, Cushman J, May WL, Martin Jr JN. Postpartum preeclampsia management with furosemide: a randomized clinical trial. Obstetrics & Gynecology 2005;105:29-33.
Barton 1990 {published data only}
  • Barton JR, Hiett AK, Conover WB. The use of nifedipine during the postpartum period in patients with severe preeclampsia. Proceedings of 10th Annual Meeting of Society of Perinatal Obstetricians; 1990 Jan 23-27; Houston, Texas, USA. 1990:307.
  • Barton JR, Hiett AK, Conover WB. The use of nifedipine during the postpartum period in patients with severe pre-eclampsia. American Journal of Obstetrics and Gynecology 1990;162:788-92.
Fidler 1992 {published data only}
Griffis 1989 {published data only}
  • Griffis KR Jr, Martin JN Jr, Palmer SM, Martin RW, Morrison JC. Utilization of hydralazine or alpha-methyldopa for the management of early puerperal hypertension. American Journal of Perinatology 1989;6:437-41.
  • Martin JN, Griffis KR, Martin RW, Hess LW, Morrison JC. Early puerperal hypertension management: hydralazine vs methyldopa. 6th International Congress of the International Society for the Study of Hypertension in Pregnancy; 1988 May 22-26; Montreal Quebec, Canada. 1988:197.
Hladunewich 2006 {published data only}
  • Hladunewich MA, Derby GC, Lafayette RA, Blouch KL, Druzin ML, Myers BD. Effect of L-arginine therapy on the glomerular injury of preeclampsia: a randomized controlled trial. Obstetrics & Gynecology 2006;107(4):886-95.
Matthews 1997 {published data only}
  • Matthews G, Gornall R, Saunders N. A randomized placebo trial of loop diuretics in moderate/severe pre-eclampsia, following delivery. Journal of Obstetrics and Gynaecology 1997;17(1):30-2.
Sayin 2005 {published data only}
  • Sayin NC, Altundag G, Varol FG. Efficacy of alpha-methyldopa and nifedipine in the treatment of postpartum hypertension [Postpartum hipertansiyon tedavisinde alfametildopa ve nifedipinin etkinligi]. Journal of the Turkish German Gynecology Association 2005;6(2):118-22.
Vigil-De Gracia 2007 {published data only}
  • Vigil-De Gracia P, Ruiz E, Lopez JC, de Jaramillo IA, Vega-Maleck JC, Pinzon J. Management of severe hypertension in the postpartum period with intravenous hydralazine or labetalol: a randomized clinical trial. Hypertension in Pregnancy 2007;26(2):163-71.
Walss Rodriguez 1991 {published data only}
  • Walss Rodriguez RJ, Villarreal Ordaz F. Severe pre-eclampsia management during puerperium. Comparative study between sublingual nifedipine and hydralazine [Manejo de preeclampsia severa en el puerperio]. Ginecologia y Obstetricia de Mexico 1991;59:207-10.

References to studies excluded from this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Adarsh 2006 {published data only}
  • Adarsh B, Reena P, Nimmi C, Singh SK. In search of accelerated recovery from eclampsia. Journal of Obstetrics and Gynaecology of India 2006;56(5):402-5.
Alkan 2006 {published data only}
  • Alkan A, Tugrul S, Oral O, Uslu H, Kose D, Catakli FT. Effects of postpartum uterine curettage on maternal well-being in severe preeclamptic patients. Clinical and Experimental Obstetrics and Gynecology 2006;33(1):55-8.
Barrilleaux 2003 {published data only}
  • Barrilleaux PS, Martin JM Jr, Klauser C, Bufkin L, May W. Adjunctive intravenous dexamethasone in patiens with severe preeclampsia not complicated by HELLP syndrome. American Journal of Obstetrics and Gynecology 2003;189(6):S94.
Belfort 1988 {published data only}
Ehrenberg 2006 {published data only}
  • Ehrenberg H, Mercer B. Abbreviated post-partum magnesium sulfate therapy for women with mild preeclampsia [abstract]. American Journal of Obstetrics and Gynecology 2004;191(6 Suppl 1):S73.
  • Ehrenberg HM, Mercer BM. Abbreviated postpartum magnesium sulfate therapy for women with mild preeclampsia: a randomized controlled trial. Obstetrics & Gynecology 2006;108(4):833-8.
Garden 1982 {published data only}
  • Garden A, Davey DA, Dommisse J. Intravenous labetalol and intravenous dihydralazine in severe hypertension in pregnancy. Clinical and Experimental Hypertension 1982;B1:371-83.
Gomez 2005 {published data only}
  • Gomez LM, De la Vega GA, Ludmir J, Padilla L, Angulo D. Immediate postpartum curettage accelerates clinical recovery in severe preeclampsia [abstract]. Obstetrics & Gynecology 2005;105(4 Suppl):111S.
Hennessy 2007 {published data only}
Jia 2007 {published data only}
  • Jia JP, Wu YX, Xie GH. Clinical observation on treatment of albuminuria in patients with pregnancy-induced hypertension syndrome in puerperium by xiaobai decoction. Chinese Journal of Integrated Traditional and Western Medicine 2007;27(7):644-6.
Keiseb 2002 {published data only}
  • Keiseb J, Moodley J, Connolly C. Comparison of the efficacy of continuous furosemide and low-dose dopamine infusion in preeclampsia/eclampsia related oliguria in the immediate postpartum period. Hypertension in Pregnancy 2002;21(3):225-34.
Livingston 2003 {published data only}
Mabie 1987 {published data only}
  • Mabie WC, Gonzalez AR, Sibai BM, Amon E. A comparative trial of labetalol and hydralazine in the acute management of severe hypertension complicating pregnancy. Obstetrics & Gynecology 1987;70:328-33.
  • Mabie WC, Gonzalez-Ruiz A, Amon E, Sibai BM. A comparative trial of labetalol and hydralazine for acute management of severe hypertension complicating pregnancy. 5th International Congress for the International Society for the Study of Hypertension in Pregnancy; 1986 July 7-10; Nottingham, UK. 1986:91.
Magann 1993 {published data only}
  • Magann EF, Martin JN, Isaacs JD, Perry KG, Martin RW, Meydrech EF. Immediate postpartum curettage: accelerated recovery from preeclampsia. American Journal of Obstetrics and Gynecology 1993;168:320.
  • Magann EF, Martin JN, Isaacs JD, Perry KG, Martin RW, Meydrech EF. Immediate postpartum curettage: accelerated recovery from severe preeclampsia. Obstetrics & Gynecology 1993;81:502-6.
Magann 1994 {published data only}
  • Magann EF, Bass JD, Chauhan SP, Perry KG, Morrison JC, Martin JN. Accelerated recovery from severe preeclampsia: uterine curettage versus nifedipine. Journal of the Society for Gynecological Investigation 1994;1(3):210-4.
Mantel 1997 {published data only}
Marsoni 1985 {published data only}
Montenegro 1985 {published data only}
Morrison 1993 {published data only}
  • Morrison JC. Curettage for severe pregnancy-induced hypertension. Personal communication.
Vermillion 1999 {published data only}
  • Scardo J, Vermillion S, Newman R, Chauhan S, Brost B. Randomized double-blinded hemodynamic study of oral nifedipine and iv labetalol in hypertensive urgencies of pregnancy. American Journal of Obstetrics and Gynecology 1999;180:S18.
  • Scardo JA, Vermillion ST, Newman RB, Chauhan SP, Hogg BB. A randomized, double-blind, hemodynamic evaluation of nifedipine and labetalol in preeclamptic hypertensive emergencies. American Journal of Obstetrics and Gynecology 1999;181(4):862-6.
  • Vermillion S, Scardo J, Newman R, Chauhan S. A prospective randomized double blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies. American Journal of Obstetrics and Gynecology 1999;180:S14.
  • Vermillion ST, Scardo JA, Newman RB, Chauhan SP. A randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy. American Journal of Obstetrics and Gynecology 1999;181(4):858-61.
Weiner 1984 {published data only}

References to ongoing studies

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Aina-Mumuney 2006 {published data only}
  • Aina-Mumuney A. Hypertonic saline use in preeclampsia (ongoing trial). ClinicalTrials.gov (http://clinicaltrials.gov/) (accessed 21 March 2006).

Additional references

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Abalos 2007
Ascarelli 1999
  • Ascarelli M, Johnson V, McCreary H, May WL, Martin JN Jr. Adjunctive postpartum treatment of preeclampsia with furosemide. Obstetrics & Gynecology 1999;180(1 Pt 2):S18.
Atterbury 1996
  • Atterbury JL, Groome LJ, Hoff C. Blood pressure changes in normotensive women readmitted in the postpartum period with severe preeclampsia/eclampsia. Journal of Maternal-Fetal Medicine 1996;5:201-5.
Bayliss 2002
  • Bayliss H, Beevers DG, Churchill D. A study of puerperal blood pressure in hypertensive and normotensive pregnancies. Hypertension in Pregnancy 2002;21(Suppl 1):33.
Beardmore 2002
Bond 1989
Bowler 2002
  • Bowler G, Habiba M, Halligan A, Waugh J, Bosio P. Automated postnatal home blood pressure monitoring - an innovative program for hypertensive mothers. Hypertension in Pregnancy 2002;21(Suppl 1):3.
Brown 2000
  • Brown MA, Hague WM, Higgins J, Lowe S, McCowan L, Oats J, et al. The detection, investigation and management of hypertension in pregnancy: executive summary. Australian and New Zealand Journal of Obstetrics and Gynaecology 2000;40(2):133-8.
Castro 1994
  • Castro LC, Hobel CJ, Gornbein J. Plasma levels of atrial natriuretic peptide in normal and hypertensive pregnancies: a meta-analysis. American Journal of Obstetrics and Gynecology 1994;171:1642-51.
Conf Enq 94-96
  • Department of Health. Why mothers die. Report on confidential inquiries into maternal deaths in the United Kingdom 1994-96. London: HMSO, 1999.
Conf Enq 97-99
  • Lewis G. Why mothers die. Report on confidential inquiries into maternal deaths in the United Kingdom 1997-99. London: RCOG Press, 2001.
Davison 1984
  • Davison JM, Dunlop W. Changes in renal hemodynamics and tubular function induced by human normal pregnancy. Seminars in Nephrology 1984;4:198-207.
Deeks 2001
  • Deeks JJ, Altman DG, Bradburn MJ. Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis. In: Egger M, Davey Smith G, Altman DG editor(s). Systematic Reviews in Health Care: Meta-analysis in Context. London: BMJ Books, 2001.
Douglas 1994
Duley 2002
Eden 1986
Ferrazzani 1994
  • Ferrazzani S, De Carolis S, Pomini F, Testa AC, Mastromarino C, Caruso A. The duration of hypertension in the puerperium of preeclamptic women: relationship with renal impairment and week of delivery. American Journal of Obstetrics and Gynecology 1994;171:506-12.
Henry 1936
Higgins 2008
  • Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 [updated September 2008]. The Cochrane Collaboration, 2008. Available from www.cochrane-handbook.org.
Higgins 2011
  • Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
Hunter 1961
  • Hunter CA Jr, Howard WF, McCormick CO Jr. Amelioration of the hypertension of toxaemia by postpartum curettage. American Journal of Obstetrics and Gynecology 1961;81:884-9.
Makris 2004
Mizutani 1993
  • Mizutani S, Tomada Y. Plasma angiotensin I concentration and serum placental leucine aminopeptidase (P-LAP) activities in puerperal hypertension. Research Communications in Chemical Pathology and Pharmacology 1993;81(3):271-91.
Nagai 1997
  • Nagai K, Ikenoue T, Mori N. Atrial natriuretic peptide in transient puerperal hypertension. Journal of Maternal-Fetal Medicine 1997;6:329-33.
NHBPEPWG 2000
  • Anonymous. Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. American Journal of Obstetrics and Gynecology 2000;183(1):S1-S22.
Ojugwu 1993
  • Ojugwu LI, Ofili UG. Morbidity and mortality from postpartum hypertension in Nigerian women. African Journal of Medicine and Medical Sciences 1993;22(1):11-6.
RevMan 2008
  • The Cochrane Collaboration. Review Manager (RevMan). 5.0. Copenhagen, The Nordic Cochrane Centre: The Cochrane Collaboration, 2008.
RevMan 2012
  • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2012.
Rey 1997
  • Rey E, LeLorier J, Burgess E, Lange IR, Leduc L. Report of the Canadian Hypertension Society Consensus Conference: 3. Pharmacologic treatment of hypertensive disorders in pregnancy. Canadian Medical Association Journal 1997;157(9):1245-54.
Robinson 1964
Tan 2002
Walters 1986
Walters 1987

References to other published versions of this review

  1. References to studies included in this review
  2. References to studies excluded from this review
  3. References to ongoing studies
  4. Additional references
  5. References to other published versions of this review
Magee 2003
  • Magee L, Sadeghi S. Prevention and treatment of postpartum hypertension. Cochrane Database of Systematic Reviews 2003, Issue 3. [DOI: 10.1002/14651858.CD004351]
Magee 2005