This is the protocol for a review and there is no abstract. The objectives are as follows:
The primary objective of this review is to determine the clinical efficacy and acceptability of antidepressants in patients with anorexia nervosa when compared to placebo.
Secondary objectives are:
(i) to investigate the efficacy and acceptability of different classes of antidepressant drugs
(ii) to evaluate the efficacy of antidepressants with respect to general psychiatric symptoms usually associated to AN and global clinical improvement.