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Antibiotics for brain abscesses in people with cyanotic congenital heart disease

  1. Pagakrong Lumbiganon*,
  2. Arnkisa Chaikitpinyo

Editorial Group: Cochrane Heart Group

Published Online: 28 MAR 2013

Assessed as up-to-date: 25 JAN 2013

DOI: 10.1002/14651858.CD004469.pub3

How to Cite

Lumbiganon P, Chaikitpinyo A. Antibiotics for brain abscesses in people with cyanotic congenital heart disease. Cochrane Database of Systematic Reviews 2013, Issue 3. Art. No.: CD004469. DOI: 10.1002/14651858.CD004469.pub3.

Author Information

  1. Faculty of Medicine, Department of Pediatrics, Khon Kaen, Thailand

*Pagakrong Lumbiganon, Department of Pediatrics, Faculty of Medicine, Khon Kaen Univeristy, Khon Kaen, 40002, Thailand.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 28 MAR 2013



References to studies excluded from this review

  1. References to studies excluded from this review
  2. Additional references
Abdullah 2001 {published data only}
British Society 2000 {published data only}
  • Infection in Neurosurgery Working Party of the British Society for Antimicrobial Chemotherapy. The rational use of antibiotics in the treatment of brain abscess. British Journal of Neurosurgery 2000;14(6):525-30.
Gonzalez-Garcia 1999 {published data only}
Hirsch 1983 {published data only}
  • Hirsch JF, Roux FX, Sainte-Rose C, Renier D, Pierre-Kahn A. Brain abscess in childhood. A study of 34 cases treated by puncture and antibiotics. Childs Brain 1983;10(4):251-65.
Jansson 2004 {published data only}
  • Jansson AK, Enblad P, Sjolin J. Efficacy and safety of cefotaxime in combination with metronidazole for empirical treatment of brain abscess in clinical practice: a retrospective study of 66 consecutive cases. European Journal of Clinical Microbiology & Infectious Diseases 2004;23:7-14.
Lu 2002 {published data only}
  • Lu CH, Chang WN, Lin YC, Tsai NW, Liliang PC, Su TM, Rau CS, Tsai YD, Liang CL, Chang CJ, Lee PY, Chang HW, Wu JJ. Bacterial brain abscess: microbiological features, epidemiological trends and therapeutic outcomes. Quarterly Journal of Medicine 2002;95:501-9.
Mampalum 1988 {published data only}
Seneviratne Rde 2003 {published data only}
  • Senevirantne Rde S, Navvasivayam P, Perera S, Wickremasinghe RS. Microbiology of cerebral abscess at the neurosurgical unit of the National Hospital of Sri Lanka. Ceylon Medical Journal 2003;48(1):14-6.
Yang 1981 {published data only}

Additional references

  1. References to studies excluded from this review
  2. Additional references
Brewer 1975
De Louvois 1978
Deeks 1998
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Mathisen 1997
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Moher 1998
  • Moher D, Pham B, Jones A, Cook DJ, Jadad AR, Moher M, et al. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?. Lancet 1998;352(9128):609-13.
Prusty 1993
  • Prusty GK. Brain abscesses in cyanotic heart disease. Indian Journal of Pediatrics 1993;60:43-51.
Saez-Llorens 1989
  • Saez-Llorens XJ, Umana MA, Odio CM, McCracken GH Jr, Nelson JD. Brain abscess in infants and children. Pediatric Infectious Disease Journal 1989;8:449-58.
Schulz 1995
  • Schulz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA 1995;273(5):408-12.
Sjolin 1991
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  • Sjolin J, Lilja A, Eriksson N, Arneborn P, Cars O. Treatment of brain abscess with cefotaxime and metronidazole: prospective study on 15 consecutive patients. Clinical Infectious Diseases 1993;17:857-63.
Takeshita 1997
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