Intervention Review

Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa

  1. John S Phillips1,*,
  2. Stephen EM Jones2

Editorial Group: Cochrane Ear, Nose and Throat Disorders Group

Published Online: 15 APR 2009

Assessed as up-to-date: 13 JAN 2011

DOI: 10.1002/14651858.CD004617.pub2

Database Title

Additional Information

How to Cite

Phillips JS, Jones SEM. Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa. Cochrane Database of Systematic Reviews 2005, Issue 2. Art. No.: CD004617. DOI: 10.1002/14651858.CD004617.pub2.

Author Information

  1. 1

    Norfolk and Norwich University Hospital NHS Trust, Department of Otolaryngology, Norwich, UK

  2. 2

    Ninewells Hospital, ENT Department, Dundee, UK

*John S Phillips, Department of Otolaryngology, Norfolk and Norwich University Hospital NHS Trust, Colney Lane, Norwich, NR4 7UY, UK. john.phillips@mac.com.

Publication History

  1. Publication Status: New search for studies and content updated (no change to conclusions)
  2. Published Online: 15 APR 2009

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Abstract

  1. Top of page
  2. Abstract
  3. Plain language summary
  4. 摘要

Background

Malignant, or necrotising, otitis externa is a potentially fatal infection of the external ear canal and surrounding soft tissue and bone. It may be complicated by involvement of cranial nerves, principally the facial nerves and the contents of the jugular foramen. It is an uncommon condition mainly found in the elderly or in diabetics.

Objectives

To assess the effectiveness of adjunctive hyperbaric oxygen treatment for malignant otitis externa.

Search methods

We searched the Cochrane Ear, Nose and Throat Disorders Group Trials Register; the Cochrane Central Register of Controlled Trials (CENTRAL); PubMed; EMBASE; CINAHL; Web of Science; BIOSIS; ICTRP and additional sources for published and unpublished trials. The date of the most recent search was 14 January 2011.

Selection criteria

Randomised controlled trials, involving adults, undergoing hyperbaric oxygen therapy in malignant otitis externa.

Data collection and analysis

No identified articles described randomised controlled trials of hyperbaric oxygen therapy in the treatment of malignant otitis externa.

Main results

Due to the lack of data we could present no results.

Authors' conclusions

No clear evidence exists to demonstrate the efficacy of hyperbaric oxygen therapy when compared to treatment with antibiotics and/or surgery. We found no data to compare rates of complication between the different treatment modalities. Further research is required.

 

Plain language summary

  1. Top of page
  2. Abstract
  3. Plain language summary
  4. 摘要

Hyperbaric oxygen as an additional treatment for malignant otitis externa

Malignant otitis externa is an uncommon, although potentially fatal, infection of the external ear canal including the surrounding soft tissue and bone. It is mainly found in the elderly or diabetics. Treatments include antibiotics, stringent diabetes control, the repeated removal of dead tissue and surgical management. Hyperbaric oxygen therapy is increasingly being used in addition to these treatments where facilities exist. Hyperbaric oxygen treatment involves placing the patient in a compression chamber, increasing the environmental pressure within the chamber, and administering 100% oxygen for respiration.

The review found no trials to demonstrate that the addition of hyperbaric oxygen therapy offers a better outcome than the treatments alone. Further research is required.

 

摘要

  1. Top of page
  2. Abstract
  3. Plain language summary
  4. 摘要

背景

用高壓氧輔助惡性外耳炎的治療

惡性外耳炎(又稱壞死性外耳炎)是外耳道, 周邊軟組織及骨頭的一種可能致死的感染, 它會併發腦神經發炎, 尤其是影響顏面神經及頸靜脈孔內的神經. 這是一種少見的疾病, 主要發生在老年人及糖尿病患者.

目標

評估用高壓氧輔助惡性外耳炎治療的效果

搜尋策略

以設定的名稱搜尋 the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library Issue 2, 2006), MEDLINE (January 1966 to June 2006) 及 EMBASE (January 1985 to June 2006). 最後搜尋日期為２００６年６月２８日

選擇標準

用高壓氧治療成人惡性外耳炎的隨機對照試驗

資料收集與分析

沒有找到用高壓氧治療惡性外耳炎的隨機對照試驗的相關文章

主要結論

由於缺少資料, 無結論可提出

作者結論

沒有明確的證據可顯示高壓氧與藥物或手術治療比較的效果, 也沒有不同治療方式下併發症發生率的比較資料. 需要更多研究.

翻譯人

本摘要由國泰綜合醫院方德詠翻譯。

此翻譯計畫由臺灣國家衛生研究院 (National Health Research Institutes, Taiwan) 統籌。

總結

沒有明確的證據顯示用高壓氧治療惡性外耳炎的效果：惡性外耳炎是個少見但卻會致命的外耳道, 周邊軟組織及骨頭的感染. 主要發生在老年人和糖尿病患者. 治療包括抗生素, 嚴格的糖尿病控制, 反覆移除壞死組織, 及手術處理. 除了這些治療方式外, 越來越多運用高壓氧來輔助治療. 此次回顧沒有找到研究來證明增加高壓氧輔助療法比單獨傳統治療有效. 需要更進一步研究

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