Intervention Review

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Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth

  1. Edmund Bailey1,*,
  2. Helen V Worthington2,
  3. Arjen van Wijk3,
  4. Julian M Yates1,
  5. Paul Coulthard1,
  6. Zahid Afzal4

Editorial Group: Cochrane Oral Health Group

Published Online: 12 DEC 2013

Assessed as up-to-date: 20 MAY 2013

DOI: 10.1002/14651858.CD004624.pub2


How to Cite

Bailey E, Worthington HV, van Wijk A, Yates JM, Coulthard P, Afzal Z. Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth. Cochrane Database of Systematic Reviews 2013, Issue 12. Art. No.: CD004624. DOI: 10.1002/14651858.CD004624.pub2.

Author Information

  1. 1

    School of Dentistry, The University of Manchester, Department of Oral and Maxillofacial Surgery, Manchester, UK

  2. 2

    School of Dentistry, The University of Manchester, Cochrane Oral Health Group, Manchester, UK

  3. 3

    Academic Centre for Dentistry Amsterdam (ACTA), Social Dentistry and Behavioural Sciences, Amsterdam, Netherlands

  4. 4

    City Hospital, Oral and Maxillofacial Surgery, Birmingham, UK

*Edmund Bailey, Department of Oral and Maxillofacial Surgery, School of Dentistry, The University of Manchester, Coupland III Building, Oxford Road, Manchester, M13 9PL, UK. edmund.bailey@manchester.ac.uk.

Publication History

  1. Publication Status: New
  2. Published Online: 12 DEC 2013

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[Figure 1]
Figure 1. Study flow diagram.
[Figure 2]
Figure 2. Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
[Figure 3]
Figure 3. Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
[Analysis 1.1]
Analysis 1.1. Comparison 1 Ibuprofen versus paracetamol, Outcome 1 Proportion of patients with > 50% max pain relief (TOTPAR) over 6 hours.
[Analysis 1.2]
Analysis 1.2. Comparison 1 Ibuprofen versus paracetamol, Outcome 2 Proportion of patients with > 50% max pain relief (TOTPAR) over 2 hours.
[Analysis 1.3]
Analysis 1.3. Comparison 1 Ibuprofen versus paracetamol, Outcome 3 Number of patients using rescue medication at 6 hours.
[Analysis 1.4]
Analysis 1.4. Comparison 1 Ibuprofen versus paracetamol, Outcome 4 Number of patients using rescue medication at 8 hours.
[Analysis 2.1]
Analysis 2.1. Comparison 2 Combined (ibuprofen and paracetamol) versus single drugs, Outcome 1 Proportion of patients with > 50% max pain relief (TOTPAR) over 6 hours.
[Analysis 2.2]
Analysis 2.2. Comparison 2 Combined (ibuprofen and paracetamol) versus single drugs, Outcome 2 Proportion of patients with > 50% max pain relief (TOTPAR) over 2 hours.
[Analysis 2.3]
Analysis 2.3. Comparison 2 Combined (ibuprofen and paracetamol) versus single drugs, Outcome 3 Number of patients using rescue medication at 8 hours.