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Intervention Protocol

Blood pressure lowering efficacy of alpha blockers for primary hypertension

  1. Balraj S Heran1,*,
  2. Gurdial Mattu2,
  3. Andrew Desouza3,
  4. James M Wright1

Editorial Group: Cochrane Hypertension Group

Published Online: 8 JUL 2009

DOI: 10.1002/14651858.CD004643

Database Title

Additional Information

How to Cite

Heran BS, Mattu G, Desouza A, Wright JM. Blood pressure lowering efficacy of alpha blockers for primary hypertension (Protocol). Cochrane Database of Systematic Reviews 2004, Issue 1. Art. No.: CD004643. DOI: 10.1002/14651858.CD004643.

Author Information

  1. 1

    University of British Columbia, Department of Anesthesiology, Pharmacology and Therapeutics, Vancouver, British Columbia, Canada

  2. 2

    Birmingham, UK

  3. 3

    Vancouver, BC, Canada

*Balraj S Heran, Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, 2176 Health Sciences Mall, Vancouver, British Columbia, V6T 1Z3, Canada. bsheran@ti.ubc.ca.

Publication History

  1. Publication Status: Unchanged
  2. Published Online: 8 JUL 2009

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Abstract

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  2. Abstract

This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary objective:
1.To quantify the dose-related systolic and/or diastolic blood pressure lowering efficacy of alpha blockers versus placebo in patients with primary hypertension.

Secondary objectives:
1.To determine the effects of alpha blockers on variability of blood pressure.
2.To determine the effects of alpha blockers on pulse pressure.
3.To quantify the dose-related effect of alpha blockers on heart rate.
4.To quantify the dose-related effect of alpha blockers on withdrawals due to adverse events.

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