Non-hormonal therapy for hot flushes in postmenopausal women

  • Protocol
  • Intervention


Claudio A Vera, Unidad de Medicina Basada en Evidencia, Facultad de Medicina, Pontificia Universidad Catolica de Chi, Silvina Hurtado 1539 Dpto 702, Providencia, Santiago, Chile.


This is the protocol for a review and there is no abstract. The objectives are as follows:

Primary Objective:
To examine the effectiveness of non-hormonal pharmacological treatments for relieving hot flushes in postmenopausal women.
In separate comparisons, we will assess non-hormonal treatments for their effectiveness in the relief of hot flushes:

  • Non-hormonal treatments versus placebo

  • Non-hormonal treatments versus hormonal replacement therapy

  • Non-hormonal treatments versus no-treatment control group

Secondary Objectives:
To determine the adverse effects of non-hormonal treatments.
To evaluate the impact on quality of life of non-hormonal treatments versus no-treatment control, placebo or hormonal replacement therapy.